Emily Carr College of Art and Design Courses 93-94

""back-to-back"" booklet - two front covers (Courses, Prospectus), text upside down in relation to each othe

Emily Carr College of Art and Design Catalogue 91-92

Muli-media (sic

Emily Carr College of Art and Design Catalogue 91-92

Muli-media (sic

Strongly Bound Surface Water Affects the Shape Evolution of Cerium Oxide Nanoparticles

The surface structure and composition of functional materials are well-known to be critically important factors controlling the surface reactivity. However, when doped the surface composition will change, and the challenge is to identify its impact on important surface processes and nanoparticle morphologies. We have begun to address this by using a combination of density functional theory and potential-based methods to investigate the effect of surface dopants on water adsorption and morphology of the technologically important material, CeO$_2$, which finds application as electrolyte in SOFCs, catalyst in soot combustion, and enzyme mimetic agents in biomedicine. We show that by mapping CeO$_2$ surface phase diagrams we can predict nanoparticle morphologies as a function of dopant, temperature, and water partial pressure. Our results show that low-temperature, undoped CeO$_2$ nanocubes with active {100} surface sites are thermodynamically stable, but at the typical high temperature, operating conditions favor polyhedra where {100} surfaces are replaced by less active {111} surfaces by surface ion migration. However, doping with trivalent cations, such as Gd$^{3+}$, will increase binding of water on the {100} surfaces and hence act to preserve the cuboidal architecture by capping the active surfaces. As surfaces tend to be decorated by impurities and dopants it is clear that their role should receive more attention and the approach we describe can be routinely applied to nanomaterials, morphologies, and associated active/inactive surfaces

Action in context - context in action: towards a grounded theory of software design

This thesis develops a model and a theory of software design. Thirty-two transcripts of interviews with software designers were analysed using the Grounded Theory method. The first set of sixteen interviews drawn from the field of Digital Interactive Multimedia (Data-set A) was used to develop the model and theory, the second set of sixteen interviews drawn from one source of technical literature (Data-set B) was used to test and enhance the initial outcomes. Final outcomes are then grounded in the general literature on problem solving and design. The model is concerned to capture a rich, holistic picture of software design. It is descriptive rather than prescriptive, concerned to capture how software design is done rather than advocate how it ought to be done. The theory is a development of the model and is presented initially as a theoretical framework and then as a series of propositions. The theoretical framework is a function of the juxtaposition of specific properties or attributes of the "core category", which uniquely explains the phenomenon. Its outcome is four design scenarios. Each scenario is of interest as an explanation of software design practice but two scenarios wherein such practice does not "fit" the design context are of most interest. It is argued that these scenarios can be used to identify and explain design breakdowns. Finally, the thesis purports to explicate the "Meta-process" - the process through which the inductive model and theory was developed. This is an unusual objective for a piece of IS research but valid nonetheless and significant, given the complexity of the research method used and the dearth of good process accounts in the IS literature and elsewhere

A Microfluidic Platform to design crosslinked Hyaluronic Acid Nanoparticles (cHANPs) for enhanced MRI

Recent advancements in imaging diagnostics have focused on the use of nanostructures that entrap Magnetic Resonance Imaging (MRI) Contrast Agents (CAs), without the need to chemically modify the clinically approved compounds. Nevertheless, the exploitation of microfluidic platforms for their controlled and continuous production is still missing. Here, a microfluidic platform is used to synthesize crosslinked Hyaluronic Acid NanoParticles (cHANPs) in which a clinically relevant MRI-CAs, gadolinium diethylenetriamine penta-acetic acid (Gd-DTPA), is entrapped. This microfluidic process facilitates a high degree of control over particle synthesis, enabling the production of monodisperse particles as small as 35 nm. Furthermore, the interference of Gd-DTPA during polymer precipitation is overcome by finely tuning process parameters and leveraging the use of hydrophilic-lipophilic balance (HLB) of surfactants and pH conditions. For both production strategies proposed to design Gd-loaded cHANPs, a boosting of the relaxation rate T(1) is observed since a T(1) of 1562 is achieved with a 10 μM of Gd-loaded cHANPs while a similar value is reached with 100 μM of the relevant clinical Gd-DTPA in solution. The advanced microfluidic platform to synthesize intravascularly-injectable and completely biocompatible hydrogel nanoparticles entrapping clinically approved CAs enables the implementation of straightforward and scalable strategies in diagnostics and therapy applications

Emily Carr Institute of Art & Design 95-96

Scholarship/awards are same as 1994-95