Differentiation between Pancreatic Ductal Adenocarcinoma and Normal Pancreatic Tissue for Treatment Response Assessment using Multi-Scale Texture Analysis of CT Images

Background: Pancreatic ductal adenocarcinoma (PDAC) is the most prevalent type of pancreas cancer with a high mortality rate and its staging is highly dependent on the extent of involvement between the tumor and surrounding vessels, facilitating treatment response assessment in PDAC. Objective: This study aims at detecting and visualizing the tumor region and the surrounding vessels in PDAC CT scan since, despite the tumors in other abdominal organs, clear detection of PDAC is highly difficult. Material and Methods: This retrospective study consists of three stages: 1) a patch-based algorithm for differentiation between tumor region and healthy tissue using multi-scale texture analysis along with L1-SVM (Support Vector Machine) classifier, 2) a voting-based approach, developed on a standard logistic function, to mitigate false detections, and 3) 3D visualization of the tumor and the surrounding vessels using ITK-SNAP software. Results: The results demonstrate that multi-scale texture analysis strikes a balance between recall and precision in tumor and healthy tissue differentiation with an overall accuracy of 0.78±0.12 and a sensitivity of 0.90±0.09 in PDAC. Conclusion: Multi-scale texture analysis using statistical and wavelet-based features along with L1-SVM can be employed to differentiate between healthy and pancreatic tissues. Besides, 3D visualization of the tumor region and surrounding vessels can facilitate the assessment of treatment response in PDAC. However, the 3D visualization software must be further developed for integrating with clinical applications

Feature extraction and selection algorithm based on self adaptive ant colony system for sky image classification

Sky image classification is crucial in meteorology to forecast weather and climatic conditions. The fine-grained cloud detection and recognition (FGCDR) algorithm is use to extract colour, inside texture and neighbour texture features from multiview of superpixels sky images. However, the FGCDR produced a substantial amount of redundant and insignificant features. The ant colony optimisation (ACO) algorithm have been used to select feature subset. However, the ACO suffers from premature convergence which leads to poor feature subset. Therefore, an improved feature extraction and selection for sky image classification (FESSIC) algorithm is proposed. This algorithm consists of (i) Gaussian smoothness standard deviation method that formulates informative features within sky images; (ii) nearest-threshold based technique that converts feature map into a weighted directed graph to represent relationship between features; and (iii) an ant colony system with self-adaptive parameter technique for local pheromone update. The performance of FESSIC was evaluated against ten benchmark image classification algorithms and six classifiers on four ground-based sky image datasets. The Friedman test result is presented for the performance rank of six benchmark feature selection algorithms and FESSIC algorithm. The Man-Whitney U test is then performed to statistically evaluate the significance difference of the second rank and FESSIC algorithms. The experimental results for the proposed algorithm are superior to the benchmark image classification algorithms in terms of similarity value on Kiel, SWIMCAT and MGCD datasets. FESSIC outperforms other algorithms for average classification accuracy for the KSVM, MLP, RF and DT classifiers. The Friedman test has shown that the FESSIC has the first rank for all classifiers. Furthermore, the result of Man-Whitney U test indicates that FESSIC is significantly better than the second rank benchmark algorithm for all classifiers. In conclusion, the FESSIC can be utilised for image classification in various applications such as disaster management, medical diagnosis, industrial inspection, sports management, and content-based image retrieval