ВОЗМОЖНОСТИ ПРИМЕНЕНИЯ УСИЛЕННОЙ НАРУЖНОЙ КОНТРПУЛЬСАЦИИ ПРИ ЛЕЧЕНИИ БОЛЬНЫХ С ЗАБОЛЕВАНИЯМИ СЕРДЦА И СОСУДОВ

SUMMARY. The article presents various aspects of enhanced external counterpulsation in treatment of patients with various cardiovascular diseases, including coronary heart disease, and also discussion on the possibility of widespread use of this method in clinical practice. The review also presents the evidence base of enhanced external counterpulsation use, and requirements for the safe and effective use of this method in patients with vascular diseases. РЕЗЮМЕ. В статье рассматриваются различные аспекты применения метода усиленной наружной контрпульсации в лечении больных с различными сосудистыми заболеваниями, включая ишемическую болезнь сердца, а также обсуждаются возможности широкого использования такого метода в условиях реальной клинической практики. Приведена доказательная база применения метода усиленной наружной контрпульсации, а также рассмотрены условия безопасного и эффективного использования такого метода при лечении больных с сосудистыми заболеваниями.

Angina Pectoris

Angina is the most common disorder affecting patients with ischemic heart disease. This book provides a thorough review of fundamental principles of diagnosis, pathophysiology and treatment of angina pectoris, representing an invaluable resource not only for cardiologists, but also for general practitioners and medical students

ESC core curriculum for the general cardiologist (2013)

[No abstract available

ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction)

Although considerable improvement has occurred in the process of care for patients with ST-elevation myocardial infarction (STEMI), room for improvement exists (1–3). The purpose of the present guideline is to focus on the numerous advances in the diagnosis and management of patients with STEMI since 1999. This is reflected in the changed name of the guideline: “ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction.” The final recommendations for indications for a diagnostic procedure, a particular therapy, or an intervention in patients with STEMI summarize both clinical evidence and expert opinion (Table 1).To provide clinicians with a set of recommendations that can easily be translated into the practice of caring for patients with STEMI, this guideline is organized around the chronology of the interface between the patient and the clinician. The full guideline is available at http://www.acc.org/clinical/guidelines/stemi/index.htm

Short term physiological changes secondary to exercise in intermittent claudication : short term physiological changes in claudication

Background: In patients with intermittent claudication (IC), supervised exercise programmes (SEP) improve walking distance and quality of life (QoL); however the mechanisms by which these benefits are achieved remain unclear.Endothelial dysfunction is recognised as a trigger of the atheroinflammatory cascade and subsequent cardiovascular disease. In health, training improves cardiorespiratory physiology, inflammation and endothelial function. Changes in cardiorespiratory physiology, inflammatory markers and endothelial function are contradictory in IC.Objectives: This thesis aimed to assess the impact of SEP on cardiopulmonary physiology, endothelial function and athero-inflammatory markers in patients with IC.Methods: Following local research ethics committee and R & D approval, patients with IC were recruited from outpatient clinic. After providing informed written consent, patients underwent baseline assessment on two separate days.Session 1: participants completed a constant load treadmill test with pre and post exercise ankle brachial pressure indices.Session 2: measured QoL, endothelial function (EndoPAT2000, Itamar, Israel), venepuncture and a cardiopulmonary exercise test (CPET) using cycle ergometry. Participants then underwent a 12 week period of SEP which consisted of circuit training, with re-assessments at six and twelve weeks. The primary outcome measure was a 1.5ml/kg/min improvement in peak VO₂ after six weeks of exercise. Secondary outcomes included changes in endothelial function, quality of life, walking distance and inflammatory markers at both six and twelve weeks.Results: No significant improvements in CPET measurements, endothelial function or inflammation were demonstrated at any time point. Traditional markers of walking ability and QoL demonstrated an improvement by 12 weeks.Conclusions: The underlying mechanism through which exercise improves walking distance remains un-identified. Further work regarding the changes at the cellular level within the muscle is of importance

2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease

The recommendations listed in this document are, whenever possible, evidence based. An extensive evidence review was conducted as the document was compiled through December 2008. Repeated literature searches were performed by the guideline development staff and writing committee members as new issues were considered. New clinical trials published in peer-reviewed journals and articles through December 2011 were also reviewed and incorporated when relevant. Furthermore, because of the extended development time period for this guideline, peer review comments indicated that the sections focused on imaging technologies required additional updating, which occurred during 2011. Therefore, the evidence review for the imaging sections includes published literature through December 2011