Family of 2-simplex cognitive tools and their application for decision-making and its justifications

Urgency of application and development of cognitive graphic tools for usage in intelligent systems of data analysis, decision making and its justifications is given. Cognitive graphic tool "2-simplex prism" and examples of its usage are presented. Specificity of program realization of cognitive graphics tools invariant to problem areas is described. Most significant results are given and discussed. Future investigations are connected with usage of new approach to rendering, cross-platform realization, cognitive features improving and expanding of n-simplex family.Comment: 14 pages, 6 figures, conferenc

Detecting barriers to transport: A review of different techniques

We review and discuss some different techniques for describing local dispersion properties in fluids. A recent Lagrangian diagnostics, based on the Finite Scale Lyapunov Exponent (FSLE), is presented and compared to the Finite Time Lyapunov Exponent (FTLE), and to the Okubo-Weiss (OW) and Hua-Klein (HK) criteria. We show that the OW and HK are a limiting case of the FTLE, and that the FSLE is the most efficient method for detecting the presence of cross-stream barriers. We illustrate our findings by considering two examples of geophysical interest: a kinematic meandering jet model, and Lagrangian tracers advected by stratospheric circulation.Comment: 15 pages, 9 figures, submitted to Physica

Nanopipettes as Monitoring Probes for the Single Living Cell: State of the Art and Future Directions in Molecular Biology.

Examining the behavior of a single cell within its natural environment is valuable for understanding both the biological processes that control the function of cells and how injury or disease lead to pathological change of their function. Single-cell analysis can reveal information regarding the causes of genetic changes, and it can contribute to studies on the molecular basis of cell transformation and proliferation. By contrast, whole tissue biopsies can only yield information on a statistical average of several processes occurring in a population of different cells. Electrowetting within a nanopipette provides a nanobiopsy platform for the extraction of cellular material from single living cells. Additionally, functionalized nanopipette sensing probes can differentiate analytes based on their size, shape or charge density, making the technology uniquely suited to sensing changes in single-cell dynamics. In this review, we highlight the potential of nanopipette technology as a non-destructive analytical tool to monitor single living cells, with particular attention to integration into applications in molecular biology