17,234 research outputs found
High Angular Resolution Stellar Imaging with Occultations from the Cassini Spacecraft II: Kronocyclic Tomography
We present an advance in the use of Cassini observations of stellar
occultations by the rings of Saturn for stellar studies. Stewart et al. (2013)
demonstrated the potential use of such observations for measuring stellar
angular diameters. Here, we use these same observations, and tomographic
imaging reconstruction techniques, to produce two dimensional images of complex
stellar systems. We detail the determination of the basic observational
reference frame. A technique for recovering model-independent brightness
profiles for data from each occulting edge is discussed, along with the
tomographic combination of these profiles to build an image of the source star.
Finally we demonstrate the technique with recovered images of the {\alpha}
Centauri binary system and the circumstellar environment of the evolved
late-type giant star, Mira.Comment: 8 pages, 8 figures, Accepted by MNRA
Evaluation of Motion Artifact Metrics for Coronary CT Angiography
Purpose
This study quantified the performance of coronary artery motion artifact metrics relative to human observer ratings. Motion artifact metrics have been used as part of motion correction and best‐phase selection algorithms for Coronary Computed Tomography Angiography (CCTA). However, the lack of ground truth makes it difficult to validate how well the metrics quantify the level of motion artifact. This study investigated five motion artifact metrics, including two novel metrics, using a dynamic phantom, clinical CCTA images, and an observer study that provided ground‐truth motion artifact scores from a series of pairwise comparisons. Method
Five motion artifact metrics were calculated for the coronary artery regions on both phantom and clinical CCTA images: positivity, entropy, normalized circularity, Fold Overlap Ratio (FOR), and Low‐Intensity Region Score (LIRS). CT images were acquired of a dynamic cardiac phantom that simulated cardiac motion and contained six iodine‐filled vessels of varying diameter and with regions of soft plaque and calcifications. Scans were repeated with different gantry start angles. Images were reconstructed at five phases of the motion cycle. Clinical images were acquired from 14 CCTA exams with patient heart rates ranging from 52 to 82 bpm. The vessel and shading artifacts were manually segmented by three readers and combined to create ground‐truth artifact regions. Motion artifact levels were also assessed by readers using a pairwise comparison method to establish a ground‐truth reader score. The Kendall\u27s Tau coefficients were calculated to evaluate the statistical agreement in ranking between the motion artifacts metrics and reader scores. Linear regression between the reader scores and the metrics was also performed. Results
On phantom images, the Kendall\u27s Tau coefficients of the five motion artifact metrics were 0.50 (normalized circularity), 0.35 (entropy), 0.82 (positivity), 0.77 (FOR), 0.77(LIRS), where higher Kendall\u27s Tau signifies higher agreement. The FOR, LIRS, and transformed positivity (the fourth root of the positivity) were further evaluated in the study of clinical images. The Kendall\u27s Tau coefficients of the selected metrics were 0.59 (FOR), 0.53 (LIRS), and 0.21 (Transformed positivity). In the study of clinical data, a Motion Artifact Score, defined as the product of FOR and LIRS metrics, further improved agreement with reader scores, with a Kendall\u27s Tau coefficient of 0.65. Conclusion
The metrics of FOR, LIRS, and the product of the two metrics provided the highest agreement in motion artifact ranking when compared to the readers, and the highest linear correlation to the reader scores. The validated motion artifact metrics may be useful for developing and evaluating methods to reduce motion in Coronary Computed Tomography Angiography (CCTA) images
Accelerated High-Resolution Photoacoustic Tomography via Compressed Sensing
Current 3D photoacoustic tomography (PAT) systems offer either high image
quality or high frame rates but are not able to deliver high spatial and
temporal resolution simultaneously, which limits their ability to image dynamic
processes in living tissue. A particular example is the planar Fabry-Perot (FP)
scanner, which yields high-resolution images but takes several minutes to
sequentially map the photoacoustic field on the sensor plane, point-by-point.
However, as the spatio-temporal complexity of many absorbing tissue structures
is rather low, the data recorded in such a conventional, regularly sampled
fashion is often highly redundant. We demonstrate that combining variational
image reconstruction methods using spatial sparsity constraints with the
development of novel PAT acquisition systems capable of sub-sampling the
acoustic wave field can dramatically increase the acquisition speed while
maintaining a good spatial resolution: First, we describe and model two general
spatial sub-sampling schemes. Then, we discuss how to implement them using the
FP scanner and demonstrate the potential of these novel compressed sensing PAT
devices through simulated data from a realistic numerical phantom and through
measured data from a dynamic experimental phantom as well as from in-vivo
experiments. Our results show that images with good spatial resolution and
contrast can be obtained from highly sub-sampled PAT data if variational image
reconstruction methods that describe the tissues structures with suitable
sparsity-constraints are used. In particular, we examine the use of total
variation regularization enhanced by Bregman iterations. These novel
reconstruction strategies offer new opportunities to dramatically increase the
acquisition speed of PAT scanners that employ point-by-point sequential
scanning as well as reducing the channel count of parallelized schemes that use
detector arrays.Comment: submitted to "Physics in Medicine and Biology
J-PET Framework: Software platform for PET tomography data reconstruction and analysis
J-PET Framework is an open-source software platform for data analysis,
written in C++ and based on the ROOT package. It provides a common environment
for implementation of reconstruction, calibration and filtering procedures, as
well as for user-level analyses of Positron Emission Tomography data. The
library contains a set of building blocks that can be combined by users with
even little programming experience, into chains of processing tasks through a
convenient, simple and well-documented API. The generic input-output interface
allows processing the data from various sources: low-level data from the
tomography acquisition system or from diagnostic setups such as digital
oscilloscopes, as well as high-level tomography structures e.g. sinograms or a
list of lines-of-response. Moreover, the environment can be interfaced with
Monte Carlo simulation packages such as GEANT and GATE, which are commonly used
in the medical scientific community.Comment: 14 pages, 5 figure
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