Hyperspectral colon tissue cell classification

A novel algorithm to discriminate between normal and malignant tissue cells of the human colon is presented. The microscopic level images of human colon tissue cells were acquired using hyperspectral imaging technology at contiguous wavelength intervals of visible light. While hyperspectral imagery data provides a wealth of information, its large size normally means high computational processing complexity. Several methods exist to avoid the so-called curse of dimensionality and hence reduce the computational complexity. In this study, we experimented with Principal Component Analysis (PCA) and two modifications of Independent Component Analysis (ICA). In the first stage of the algorithm, the extracted components are used to separate four constituent parts of the colon tissue: nuclei, cytoplasm, lamina propria, and lumen. The segmentation is performed in an unsupervised fashion using the nearest centroid clustering algorithm. The segmented image is further used, in the second stage of the classification algorithm, to exploit the spatial relationship between the labeled constituent parts. Experimental results using supervised Support Vector Machines (SVM) classification based on multiscale morphological features reveal the discrimination between normal and malignant tissue cells with a reasonable degree of accuracy

Multivariate texture discrimination based on geodesics to class centroids on a generalized Gaussian Manifold

A texture discrimination scheme is proposed wherein probability distributions are deployed on a probabilistic manifold for modeling the wavelet statistics of images. We consider the Rao geodesic distance (GD) to the class centroid for texture discrimination in various classification experiments. We compare the performance of GD to class centroid with the Euclidean distance in a similar context, both in terms of accuracy and computational complexity. Also, we compare our proposed classification scheme with the k-nearest neighbor algorithm. Univariate and multivariate Gaussian and Laplace distributions, as well as generalized Gaussian distributions with variable shape parameter are each evaluated as a statistical model for the wavelet coefficients. The GD to the centroid outperforms the Euclidean distance and yields superior discrimination compared to the k-nearest neighbor approach

Local wavelet features for statistical object classification and localisation

This article presents a system for texture-based probabilistic classification and localisation of 3D objects in 2D digital images and discusses selected applications. The objects are described by local feature vectors computed using the wavelet transform. In the training phase, object features are statistically modelled as normal density functions. In the recognition phase, a maximisation algorithm compares the learned density functions with the feature vectors extracted from a real scene and yields the classes and poses of objects found in it. Experiments carried out on a real dataset of over 40000 images demonstrate the robustness of the system in terms of classification and localisation accuracy. Finally, two important application scenarios are discussed, namely classification of museum artefacts and classification of metallography images

Multiple multidimensional morse wavelets

This paper defines a set of operators that localize a radial image in space and radial frequency simultaneously. The eigenfunctions of the operator are determined and a nonseparable orthogonal set of radial wavelet functions are found. The eigenfunctions are optimally concentrated over a given region of radial space and scale space, defined via a triplet of parameters. Analytic forms for the energy concentration of the functions over the region are given. The radial function localization operator can be generalised to an operator localizing any L-2(R-2) function. It is demonstrated that the latter operator, given an appropriate choice of localization region, approximately has the same radial eigenfunctions as the radial operator. Based on a given radial wavelet function a quaternionic wavelet is defined that can extract the local orientation of discontinuous signals as well as amplitude, orientation and phase structure of locally oscillatory signals. The full set of quaternionic wavelet functions are component by component orthogonal; their statistical properties are tractable, and forms for the variability of the estimators of the local phase and orientation are given, as well as the local energy of the image. By averaging estimators across wavelets, a substantial reduction in the variance is achieved