19 research outputs found

    Enabling Technology in Optical Fiber Communications: From Device, System to Networking

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    This book explores the enabling technology in optical fiber communications. It focuses on the state-of-the-art advances from fundamental theories, devices, and subsystems to networking applications as well as future perspectives of optical fiber communications. The topics cover include integrated photonics, fiber optics, fiber and free-space optical communications, and optical networking

    Protein crystals as nanotemplating materials

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    2019 Spring.Includes bibliographical references.The advancement of nanomaterial development depends on the reliable and scalable synthesis of three dimensional nanostructures and devices. Applications for these materials range from catalysis and energy storage to biomedicine and imaging. Towards the goals of shape-controlled immobilization and synthesis, templating is arising as a promising manufacturing method. With the rise of bionanotechnology, DNA and protein scaffolds can be designed, synthesized, and functionalized to coordinate nanoparticles, enzymes, and other guests in three dimensions, or act as molds for the synthesis of anisotropic nanostructures. Inherently, protein crystals are an attractive target, as they have nearly unlimited designability, intrinsic functionality for a variety of useful materials, and mild reaction conditions. The overarching goal of this work is to explore the feasibility of protein crystals as templates for the creation of biohybrid materials. We show that protein crystals with large solvent channels can strongly adsorb and immobilize gold nanoparticles by reversible metal affinity interactions and that these nanoparticles can serve as nucleation sites for the growth of nanorods within the pores of protein crystals by a variety of gold growth methods. We show that, depending on the method used, gold nanorod synthesis within the crystals can be dependent on the presence of a seed particle. Despite their stability, these crystals can be dissolved to release the gold structures, which can be analyzed by electron microscopy and elemental analysis. A variety of gold nanorod products are formed, from highly anisotropic individual rods, to interconnected rod bundles, to parallel rods embedded within a protein matrix. Additionally, we show that protein crystal pores can be used for the long-term capture of multiple enzymes and that these enzymes retain their activity within the crystal. Product can be separated by a simple washing step, and the immobilized two-enzyme pathway can be used for multiple cycles over several weeks. Rates of product formation are higher for enzymes immobilized within crystals of a high surface-to-volume ratio; thus, the use of micron-sized crystals minimizes transport limitations typically associated with enzyme immobilization. Preliminary work suggests the crystals may also impart significant thermal stability to the embedded enzymes. Porous protein crystals may provide a superior templating method for the development of nanomaterials. Here we further demonstrate the wide variety of applications for protein crystals by revealing their success as scaffolds for immobilization, synthesis, and catalysis

    Technology 2003: Conference Proceedings from the Fourth National Technology Transfer Conference and Exposition, Volume 1

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    Proceedings from symposia of the Technology 2003 Conference and Exposition, December 7-9, I993, Anaheim, CA. Volume 1 features the Plenary Session and the Plenary Workshop, plus papers presented in Advanced Manufacturing, Biotechnology/Medical Technology, Environmental Technology, Materials Science, and Power and Energy

    Thrust Area Report, Engineering Research, Development and Technology

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    ESSE 2017. Proceedings of the International Conference on Environmental Science and Sustainable Energy

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    Environmental science is an interdisciplinary academic field that integrates physical-, biological-, and information sciences to study and solve environmental problems. ESSE - The International Conference on Environmental Science and Sustainable Energy provides a platform for experts, professionals, and researchers to share updated information and stimulate the communication with each other. In 2017 it was held in Suzhou, China June 23-25, 2017

    Life Sciences Program Tasks and Bibliography for FY 1997

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    This document includes information on all peer reviewed projects funded by the Office of Life and Microgravity Sciences and Applications, Life Sciences Division during fiscal year 1997. This document will be published annually and made available to scientists in the space life sciences field both as a hard copy and as an interactive internet web page

    Molecular Imaging

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    The present book gives an exceptional overview of molecular imaging. Practical approach represents the red thread through the whole book, covering at the same time detailed background information that goes very deep into molecular as well as cellular level. Ideas how molecular imaging will develop in the near future present a special delicacy. This should be of special interest as the contributors are members of leading research groups from all over the world

    Translational Cell & Animal Research in Space 1965-2011

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    Translational Cell and Animal Research (TCAR). For nearly 50 years, the NASA Space Biology Program has funded, and Ames Research Center (ARC) has managed, a robust program of fundamental research including studies using a wide range of animal cells, tissues and organisms. Much of this research was conducted on spacecraft in microgravity environments including diverse platforms such as: Gemini Spacecraft, US Biosatellites, Apollo Command Modules, Skylabs, Russian Biosatellites, NASA Space Shuttles, NASA/Mir, and most recently, the International Space Station (ISS). During the Space Shuttle Era (19812011), the science of space biology took an enormous step forward with 45 missions that afforded researchers with new opportunities to conduct systematic and complex experiments aimed at a deeper understanding of how life adapts to the space environment. Beginning in the 1990s, the products of these experiments, comprised of research summaries and rare, unused biospecimens, were collected and catalogued within the ARC Life Sciences Data Archiving Office, a branch of NASAs Life Sciences Data Archive (LSDA) managed from the NASA Johnson Spaceflight Center

    NASA Tech Briefs, Fall 1985

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    Topics include: NASA TU Services; New Product Ideas; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences
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