Robust CNN-based Respiration Rate Estimation for Smartwatch PPG and IMU

Respiratory rate (RR) serves as an indicator of various medical conditions, such as cardiovascular diseases and sleep disorders. These RR estimation methods were mostly designed for finger-based PPG collected from subjects in stationary situations (e.g., in hospitals). In contrast to finger-based PPG signals, wrist-based PPG are more susceptible to noise, particularly in their low frequency range, which includes respiratory information. Therefore, the existing methods struggle to accurately extract RR when PPG data are collected from wrist area under free-living conditions. The increasing popularity of smartwatches, equipped with various sensors including PPG, has prompted the need for a robust RR estimation method. In this paper, we propose a convolutional neural network-based approach to extract RR from PPG, accelerometer, and gyroscope signals captured via smartwatches. Our method, including a dilated residual inception module and 1D convolutions, extract the temporal information from the signals, enabling RR estimation. Our method is trained and tested using data collected from 36 subjects under free-living conditions for one day using Samsung Gear Sport watches. For evaluation, we compare the proposed method with four state-of-the-art RR estimation methods. The RR estimates are compared with RR references obtained from a chest-band device. The results show that our method outperforms the existing methods with the Mean-Absolute-Error and Root-Mean-Square-Error of 1.85 and 2.34, while the best results obtained by the other methods are 2.41 and 3.29, respectively. Moreover, compared to the other methods, the absolute error distribution of our method was narrow (with the lowest median), indicating a higher level of agreement between the estimated and reference RR values

Imaging photoplethysmography: towards effective physiological measurements

Since its conception decades ago, Photoplethysmography (PPG) the non-invasive opto-electronic technique that measures arterial pulsations in-vivo has proven its worth by achieving and maintaining its rank as a compulsory standard of patient monitoring. However successful, conventional contact monitoring mode is not suitable in certain clinical and biomedical situations, e.g., in the case of skin damage, or when unconstrained movement is required. With the advance of computer and photonics technologies, there has been a resurgence of interest in PPG and one potential route to overcome the abovementioned issues has been increasingly explored, i.e., imaging photoplethysmography (iPPG). The emerging field of iPPG offers some nascent opportunities in effective and comprehensive interpretation of the physiological phenomena, indicating a promising alternative to conventional PPG. Heart and respiration rate, perfusion mapping, and pulse rate variability have been accessed using iPPG. To effectively and remotely access physiological information through this emerging technique, a number of key issues are still to be addressed. The engineering issues of iPPG, particularly the influence of motion artefacts on signal quality, are addressed in this thesis, where an engineering model based on the revised Beer-Lambert law was developed and used to describe opto-physiological phenomena relevant to iPPG. An iPPG setup consisting of both hardware and software elements was developed to investigate its reliability and reproducibility in the context of effective remote physiological assessment. Specifically, a first study was conducted for the acquisition of vital physiological signs under various exercise conditions, i.e. resting, light and heavy cardiovascular exercise, in ten healthy subjects. The physiological parameters derived from the images captured by the iPPG system exhibited functional characteristics comparable to conventional contact PPG, i.e., maximum heart rate difference was <3 bpm and a significant (p < 0.05) correlation between both measurements were also revealed. Using a method for attenuation of motion artefacts, the heart rate and respiration rate information was successfully assessed from different anatomical locations even in high-intensity physical exercise situations. This study thereby leads to a new avenue for noncontact sensing of vital signs and remote physiological assessment, showing clear and promising applications in clinical triage and sports training. A second study was conducted to remotely assess pulse rate variability (PRV), which has been considered a valuable indicator of autonomic nervous system (ANS) status. The PRV information was obtained using the iPPG setup to appraise the ANS in ten normal subjects. The performance of the iPPG system in accessing PRV was evaluated via comparison with the readings from a contact PPG sensor. Strong correlation and good agreement between these two techniques verify the effectiveness of iPPG in the remote monitoring of PRV, thereby promoting iPPG as a potential alternative to the interpretation of physiological dynamics related to the ANS. The outcomes revealed in the thesis could present the trend of a robust non-contact technique for cardiovascular monitoring and evaluation

Independent component analysis for fetal heart rate detection using photosplethysmography

Photoplethysmography (PPG) is an optoelectronic technique for measuring and recording changes in the volume of body parts. These changes are associated with each heart beat and acquired by pulse oximetry. Fetal heart rate (FHR) monitoring using PPG is a challenging task since the acquired signals present the pattern of both fetal and maternal hearts. The effect of maternal component, noise and artifacts on fetal component makes the separation of FHR very difficult. In this paper, we study the applicability of independent component analysis (lCA) to FHR detection using PPG. The study was conducted using emulated signals to mimic the pulsation nature of both maternal and fetal hearts. The outcome of this experiment shows encouraging results in terms of the extraction ability oflCA, which can perform well even when fetal-to-maternal signal-to-noise ratio (SIY~) drops to -276 dB

Motion Artifact Reduction in Impedance Plethysmography Signal

The research related to designing portable monitoring devices for physiological signals has been at its peak in the last decade or two. One of the main obstacles in building such devices is the effect of the subject\u27s movements on the quality of the signal. There have been numerous studies addressing the problem of removing motion artifact from the electrocardiogram (ECG) and photoplethysmography (PPG) signals in the past few years. However, no such study exists for the Impedance Plethysmography (IP) signal. The IP signal can be used to monitor respiration in mobile devices. However, it is very susceptible to motion artifact. The main aim of this dissertation is to develop adaptive and non-adaptive filtering algorithms to address the problem of motion artifact reduction from the IP signal

VOLUNTARY CONTROL OF BREATHING ACCORDING TO THE BREATHING PATTERN DURING LISTENING TO MUSIC AND NON-CONTACT MEASUREMENT OF HEART RATE AND RESPIRATION

We investigated if listening to songs changes breathing pattern which changes autonomic responses such as heart rate (HR) and heart rate variability (HRV) or change in breathing pattern is a byproduct of listening to songs or change in breathing pattern as well as listening to songs causes changes in autonomic responses. Seven subjects (4 males and 3 females) participated in a pilot study where they listened to two types of songs and used a custom developed biofeedback program to control their breathing pattern to match the one recorded during listening to the songs. Coherencies between EEG, breathing pattern and RR intervals (RRI) were calculated to study the interaction with neural responses. Trends in HRV varied only during listening to songs, suggesting that autonomic response was affected by listening to songs irrespective of control of breathing. Effective coherence during songs while spontaneously breathing was more than during silence and during control of breathing. These results, although preliminary, suggest that listening to songs as well as change in breathing patterns changes the autonomic response but the effect of listening to songs may surpass the effect of changes in breathing. We explored feasibility of using non-contact measurements of HR and breathing rate (BR) by using recently developed Facemesh and other methods for tracking regions of interests from videos of faces of subjects. Performance was better for BR than HR, and over currently used methods. However, refinement of the approach would be needed to get the precision required for detecting subtle changes

An SoC-Based System for Real-time Contactless Measurement of Human Vital Signs and Soft Biometrics

Computer vision (CV) plays big role in our current society's life style. The advancement of CV technology brings the capability to sense human vital sign and soft biometric parameters in contactless way. In this work, we design and implement the contactless human vital sign parameters measurement including pulse rate (PR) and respiration rate (RR) and also for assessment of human soft biometric parameters i.e. age, gender, skin color type, and body height. Our designed system is based on system on chip (SoC) device which run both FPGA and hard processor while provides real-time operation and small form factor. Experimental results shows our device performance has mean absolute error (MAE) 2.85 and 1.46 bpm for PR and RR respectively compared to clinical apparatus. While, for soft biometric parameters measurement we got unsatisfied results on age and gender estimation with accuracy of 58% and 74% respectively. However, for skin color type and body height measurement we reach high accuracy with 98 % and 2.28 cm respectively on both parameters

Self-Supervised Blind Source Separation via Multi-Encoder Autoencoders

The task of blind source separation (BSS) involves separating sources from a mixture without prior knowledge of the sources or the mixing system. This is a challenging problem that often requires making restrictive assumptions about both the mixing system and the sources. In this paper, we propose a novel method for addressing BSS of non-linear mixtures by leveraging the natural feature subspace specialization ability of multi-encoder autoencoders with fully self-supervised learning without strong priors. During the training phase, our method unmixes the input into the separate encoding spaces of the multi-encoder network and then remixes these representations within the decoder for a reconstruction of the input. Then to perform source inference, we introduce a novel encoding masking technique whereby masking out all but one of the encodings enables the decoder to estimate a source signal. To this end, we also introduce a so-called pathway separation loss that encourages sparsity between the unmixed encoding spaces throughout the decoder's layers and a so-called zero reconstruction loss on the decoder for coherent source estimations. In order to carefully evaluate our method, we conduct experiments on a toy dataset and with real-world biosignal recordings from a polysomnography sleep study for extracting respiration.Comment: 17 pages, 8 figures, submitted to Information Science