998,491 research outputs found

    Predicting Risk for Deer-Vehicle Collisions Using a Social Media Based Geographic Information System

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    As an experiment investigating social media as a data source for making management decisions, photo sharing websites were searched for data on deer sightings. Data about deer density and location are important factors in decisions related to herd management and transportation safety, but such data are often limited or not available. Results indicate that when combined with simple rules, data from photo sharing websites reliably predicted the location of road segments with high risk for deer-vehicle collisions as reported by volunteers to an internet site tracking roadkill. Use of Google Maps as the GIS platform was helpful in plotting and sharing data, measuring road segments and other distances, and overlaying geographical data. The ability to view satellite images and panoramic street views proved to be a particularly useful. As a general conclusion, the two independently collected sets of data from social media provided consistent information, suggesting investigative value to this data source. Overlaying two independently collected data sets can be a useful step in evaluating or mitigating reporting bias and human error in data taken from social media

    A comparison of reimbursement recommendations by European HTA agencies : Is there opportunity for further alignment?

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    Introduction: In Europe and beyond, the rising costs of healthcare and limited healthcare resources have resulted in the implementation of health technology assessment (HTA) to inform health policy and reimbursement decision-making. European legislation has provided a harmonized route for the regulatory process with the European Medicines Agency, but reimbursement decision-making still remains the responsibility of each country. There is a recognized need to move toward a more objective and collaborative reimbursement environment for new medicines in Europe. Therefore, the aim of this study was to objectively assess and compare the national reimbursement recommendations of 9 European jurisdictions following European Medicines Agency (EMA) recommendation for centralized marketing authorization. Methods: Using publicly available data and newly developed classification tools, this study appraised 9 European reimbursement systems by assessing HTA processes and the relationship between the regulatory, HTA and decision-making organizations. Each national HTA agency was classified according to two novel taxonomies. The System taxonomy, focuses on the position of the HTA agency within the national reimbursement system according to the relationship between the regulator, the HTA-performing agency, and the reimbursement decision-making coverage body. The HTA Process taxonomy distinguishes between the individual HTA agency's approach to economic and therapeutic evaluation and the inclusion of an independent appraisal step. The taxonomic groups were subsequently compared with national HTA recommendations. Results: This study identified European national reimbursement recommendations for 102 new active substances (NASs) approved by the EMA from 2008 to 2012. These reimbursement recommendations were compared using a novel classification tool and identified alignment between the organizational structure of reimbursement systems (System taxonomy) and HTA recommendations. However, there was less alignment between the HTA processes and recommendations. Conclusions: In order to move forward to a more harmonized HTA environment within Europe, it is first necessary to understand the variation in HTA practices within Europe. This study has identified alignment between HTA recommendations and the System taxonomy and one of the major implications of this study is that such alignment could support a more collaborative HTA environment in Europe.Peer reviewedFinal Published versio

    A comparative study of multiple-criteria decision-making methods under stochastic inputs

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    This paper presents an application and extension of multiple-criteria decision-making (MCDM) methods to account for stochastic input variables. More in particular, a comparative study is carried out among well-known and widely-applied methods in MCDM, when applied to the reference problem of the selection of wind turbine support structures for a given deployment location. Along with data from industrial experts, six deterministic MCDM methods are studied, so as to determine the best alternative among the available options, assessed against selected criteria with a view toward assigning confidence levels to each option. Following an overview of the literature around MCDM problems, the best practice implementation of each method is presented aiming to assist stakeholders and decision-makers to support decisions in real-world applications, where many and often conflicting criteria are present within uncertain environments. The outcomes of this research highlight that more sophisticated methods, such as technique for the order of preference by similarity to the ideal solution (TOPSIS) and Preference Ranking Organization method for enrichment evaluation (PROMETHEE), better predict the optimum design alternative

    A multicriteria analysis of photovoltaic systems: Energetic, environmental, and economic assessments

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    The development of photovoltaic (PV) energy has led to rising efficiencies, better reliability, and falling prices. A multicriteria analysis (MCA) of PV systems is proposed in this paper in order to evaluate the sustainability of alternative projects. The investigations are presented using multiple indicators: Energy Payback Time (EPBT), Energy Return on Investment (EROI), Greenhouse Gas per kilowatt-hour (GHG/kWh), Greenhouse Gas Payback Time (GPBT), Greenhouse Gas Return on Investment (GROI), Net Present Value (NPV), Discounted Payback Time (DPBT), and Discounted Aggregate Cost Benefit (D(B/C) A). PV energy is a relevant player in global electricity market and can have a key-role in sustainable growth
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