Evolutionary multi-objective training set selection of data instances and augmentations for vocal detection

© Springer Nature Switzerland AG 2019. The size of publicly available music data sets has grown significantly in recent years, which allows training better classification models. However, training on large data sets is time-intensive and cumbersome, and some training instances might be unrepresentative and thus hurt classification performance regardless of the used model. On the other hand, it is often beneficial to extend the original training data with augmentations, but only if they are carefully chosen. Therefore, identifying a “smart” selection of training instances should improve performance. In this paper, we introduce a novel, multi-objective framework for training set selection with the target to simultaneously minimise the number of training instances and the classification error. Experimentally, we apply our method to vocal activity detection on a multi-track database extended with various audio augmentations for accompaniment and vocals. Results show that our approach is very effective at reducing classification error on a separate validation set, and that the resulting training set selections either reduce classification error or require only a small fraction of training instances for comparable performance

Business intelligence appraisal based on customer behaviour profile by using hobby based opinion mining in India: a case study

This research study contributes towards understanding the customer’s behaviour dynamics. In business analysis, it is very important not to ignore the fact that the interaction between human beings implicitly includes an emotional dimension. The research methodology includes the following: (1) customer purchase pattern prediction methods based on correlation; (2) augmentation of data set by using genetic algorithms; and (3) multiple regression models. The analysis indicates how the hobby of a customer is directly related to the purchase patterns and satisfaction level. We applied business intelligence (BI) techniques and concluded that, by using multiple regression method is possible to evaluate the level of customer satisfaction up to the upper limit of security of about 90%. BI tools could be used to employ significant achievements in specific fields based on open innovations. This paper aims at providing further practical guidance in this innovative research field by using a mix of interdisciplinary methods and techniques

Data-Centric Foundation Models in Computational Healthcare: A Survey

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has ignited a data-centric AI paradigm that emphasizes better data characterization, quality, and scale. In healthcare AI, obtaining and processing high-quality clinical data records has been a longstanding challenge, ranging from data quantity, annotation, patient privacy, and ethics. In this survey, we investigate a wide range of data-centric approaches in the FM era (from model pre-training to inference) towards improving the healthcare workflow. We discuss key perspectives in AI security, assessment, and alignment with human values. Finally, we offer a promising outlook of FM-based analytics to enhance the performance of patient outcome and clinical workflow in the evolving landscape of healthcare and medicine. We provide an up-to-date list of healthcare-related foundation models and datasets at https://github.com/Yunkun-Zhang/Data-Centric-FM-Healthcare

Detection of myocardial infarction based on novel deep transfer learning methods for urban healthcare in smart cities

YesOne of the common cardiac disorders is a cardiac attack called Myocardial infarction (MI), which occurs due to the blockage of one or more coronary arteries. Timely treatment of MI is important and slight delay results in severe consequences. Electrocardiogram (ECG) is the main diagnostic tool to monitor and reveal the MI signals. The complex nature of MI signals along with noise poses challenges to doctors for accurate and quick diagnosis. Manually studying large amounts of ECG data can be tedious and time-consuming. Therefore, there is a need for methods to automatically analyze the ECG data and make diagnosis. Number of studies has been presented to address MI detection, but most of these methods are computationally expensive and faces the problem of overfitting while dealing real data. In this paper, an effective computer-aided diagnosis (CAD) system is presented to detect MI signals using the convolution neural network (CNN) for urban healthcare in smart cities. Two types of transfer learning techniques are employed to retrain the pre-trained VGG-Net (Fine-tuning and VGG-Net as fixed feature extractor) and obtained two new networks VGG-MI1 and VGG-MI2. In the VGG-MI1 model, the last layer of the VGG-Net model is replaced with a specific layer according to our requirements and various functions are optimized to reduce overfitting. In the VGG-MI2 model, one layer of the VGG-Net model is selected as a feature descriptor of the ECG images to describe it with informative features. Considering the limited availability of dataset, ECG data is augmented which has increased the classification performance. A standard well-known database Physikalisch-Technische Bundesanstalt (PTB) Diagnostic ECG is used for the validation of the proposed framework. It is evident from experimental results that the proposed framework achieves a high accuracy surpasses the existing methods. In terms of accuracy, sensitivity, and specificity; VGG-MI1 achieved 99.02%, 98.76%, and 99.17%, respectively, while VGG-MI2 models achieved an accuracy of 99.22%, a sensitivity of 99.15%, and a specificity of 99.49%.This project was funded by University of Jeddah, Jeddah, Saudi Arabia (Project number: UJ-02-018-ICGR)

Deep Functional Mapping For Predicting Cancer Outcome

The effective understanding of the biological behavior and prognosis of cancer subtypes is becoming very important in-patient administration. Cancer is a diverse disorder in which a significant medical progression and diagnosis for each subtype can be observed and characterized. Computer-aided diagnosis for early detection and diagnosis of many kinds of diseases has evolved in the last decade. In this research, we address challenges associated with multi-organ disease diagnosis and recommend numerous models for enhanced analysis. We concentrate on evaluating the Magnetic Resonance Imaging (MRI), Computed Tomography (CT), and Positron Emission Tomography (PET) for brain, lung, and breast scans to detect, segment, and classify types of cancer from biomedical images. Moreover, histopathological, and genomic classification of cancer prognosis has been considered for multi-organ disease diagnosis and biomarker recommendation. We considered multi-modal, multi-class classification during this study. We are proposing implementing deep learning techniques based on Convolutional Neural Network and Generative Adversarial Network. In our proposed research we plan to demonstrate ways to increase the performance of the disease diagnosis by focusing on a combined diagnosis of histology, image processing, and genomics. It has been observed that the combination of medical imaging and gene expression can effectively handle the cancer detection situation with a higher diagnostic rate rather than considering the individual disease diagnosis. This research puts forward a blockchain-based system that facilitates interpretations and enhancements pertaining to automated biomedical systems. In this scheme, a secured sharing of the biomedical images and gene expression has been established. To maintain the secured sharing of the biomedical contents in a distributed system or among the hospitals, a blockchain-based algorithm is considered that generates a secure sequence to identity a hash key. This adaptive feature enables the algorithm to use multiple data types and combines various biomedical images and text records. All data related to patients, including identity, pathological records are encrypted using private key cryptography based on blockchain architecture to maintain data privacy and secure sharing of the biomedical contents

Artificial Intelligence-Powered Chronic Wound Management System: Towards Human Digital Twins

Artificial Intelligence (AI) has witnessed increased application and widespread adoption over the past decade. AI applications to medical images have the potential to assist caregivers in deciding on a proper chronic wound treatment plan by helping them to understand wound and tissue classification and border segmentation, as well as visual image synthesis. This dissertation explores chronic wound management using AI methods, such as Generative Adversarial Networks (GAN) and Explainable AI (XAI) techniques. The wound images are collected, grouped, and processed. One primary objective of this research is to develop a series of AI models, not only to present the potential of AI in wound management but also to develop the building blocks of human digital twins. First of all, motivations, contributions, and the dissertation outline are summarized to introduce the aim and scope of the dissertation. The first contribution of this study is to build a chronic wound classification and its explanation utilizing XAI. This model also benefits from a transfer learning methodology to improve performance. Then a novel model is developed that achieves wound border segmentation and tissue classification tasks simultaneously. A Deep Learning (DL) architecture, i.e., the GAN, is proposed to realize these tasks. Another novel model is developed for creating lifelike wounds. The output of the previously proposed model is used as an input for this model, which generates new chronic wound images. Any tissue distribution could be converted to lifelike wounds, preserving the shape of the original wound. The aforementioned research is extended to build a digital twin for chronic wound management. Chronic wounds, enabling technologies for wound care digital twins, are examined, and a general framework for chronic wound management using the digital twin concept is investigated. The last contribution of this dissertation includes a chronic wound healing prediction model using DL techniques. It utilizes the previously developed AI models to build a chronic wound management framework using the digital twin concept. Lastly, the overall conclusions are drawn. Future challenges and further developments in chronic wound management are discussed by utilizing emerging technologies

IoT in smart communities, technologies and applications.

Internet of Things is a system that integrates different devices and technologies, removing the necessity of human intervention. This enables the capacity of having smart (or smarter) cities around the world. By hosting different technologies and allowing interactions between them, the internet of things has spearheaded the development of smart city systems for sustainable living, increased comfort and productivity for citizens. The Internet of Things (IoT) for Smart Cities has many different domains and draws upon various underlying systems for its operation, in this work, we provide a holistic coverage of the Internet of Things in Smart Cities by discussing the fundamental components that make up the IoT Smart City landscape, the technologies that enable these domains to exist, the most prevalent practices and techniques which are used in these domains as well as the challenges that deployment of IoT systems for smart cities encounter and which need to be addressed for ubiquitous use of smart city applications. It also presents a coverage of optimization methods and applications from a smart city perspective enabled by the Internet of Things. Towards this end, a mapping is provided for the most encountered applications of computational optimization within IoT smart cities for five popular optimization methods, ant colony optimization, genetic algorithm, particle swarm optimization, artificial bee colony optimization and differential evolution. For each application identified, the algorithms used, objectives considered, the nature of the formulation and constraints taken in to account have been specified and discussed. Lastly, the data setup used by each covered work is also mentioned and directions for future work have been identified. Within the smart health domain of IoT smart cities, human activity recognition has been a key study topic in the development of cyber physical systems and assisted living applications. In particular, inertial sensor based systems have become increasingly popular because they do not restrict users’ movement and are also relatively simple to implement compared to other approaches. Fall detection is one of the most important tasks in human activity recognition. With an increasingly aging world population and an inclination by the elderly to live alone, the need to incorporate dependable fall detection schemes in smart devices such as phones, watches has gained momentum. Therefore, differentiating between falls and activities of daily living (ADLs) has been the focus of researchers in recent years with very good results. However, one aspect within fall detection that has not been investigated much is direction and severity aware fall detection. Since a fall detection system aims to detect falls in people and notify medical personnel, it could be of added value to health professionals tending to a patient suffering from a fall to know the nature of the accident. In this regard, as a case study for smart health, four different experiments have been conducted for the task of fall detection with direction and severity consideration on two publicly available datasets. These four experiments not only tackle the problem on an increasingly complicated level (the first one considers a fall only scenario and the other two a combined activity of daily living and fall scenario) but also present methodologies which outperform the state of the art techniques as discussed. Lastly, future recommendations have also been provided for researchers

Innovations in Medical Image Analysis and Explainable AI for Transparent Clinical Decision Support Systems

This thesis explores innovative methods designed to assist clinicians in their everyday practice, with a particular emphasis on Medical Image Analysis and Explainability issues. The main challenge lies in interpreting the knowledge gained from machine learning algorithms, also called black-boxes, to provide transparent clinical decision support systems for real integration into clinical practice. For this reason, all work aims to exploit Explainable AI techniques to study and interpret the trained models. Given the countless open problems for the development of clinical decision support systems, the project includes the analysis of various data and pathologies. The main works are focused on the most threatening disease afflicting the female population: Breast Cancer. The works aim to diagnose and classify breast cancer through medical images by taking advantage of a first-level examination such as Mammography screening, Ultrasound images, and a more advanced examination such as MRI. Papers on Breast Cancer and Microcalcification Classification demonstrated the potential of shallow learning algorithms in terms of explainability and accuracy when intelligible radiomic features are used. Conversely, the union of deep learning and Explainable AI methods showed impressive results for Breast Cancer Detection. The local explanations provided via saliency maps were critical for model introspection, as well as increasing performance. To increase trust in these systems and aspire to their real use, a multi-level explanation was proposed. Three main stakeholders who need transparent models have been identified: developers, physicians, and patients. For this reason, guided by the enormous impact of COVID-19 in the world population, a fully Explainable machine learning model was proposed for COVID-19 Prognosis prediction exploiting the proposed multi-level explanation. It is assumed that such a system primarily requires two components: 1) inherently explainable inputs such as clinical, laboratory, and radiomic features; 2) Explainable methods capable of explaining globally and locally the trained model. The union of these two requirements allows the developer to detect any model bias, the doctor to verify the model findings with clinical evidence, and justify decisions to patients. These results were also confirmed for the study of coronary artery disease. In particular machine learning algorithms are trained using intelligible clinical and radiomic features extracted from pericoronaric adipose tissue to assess the condition of coronary arteries. Eventually, some important national and international collaborations led to the analysis of data for the development of predictive models for some neurological disorders. In particular, the predictivity of handwriting features for the prediction of depressed patients was explored. Using the training of neural networks constrained by first-order logic, it was possible to provide high-performance and explainable models, going beyond the trade-off between explainability and accuracy

Knowledge-Informed Machine Learning for Cancer Diagnosis and Prognosis: A review

Cancer remains one of the most challenging diseases to treat in the medical field. Machine learning has enabled in-depth analysis of rich multi-omics profiles and medical imaging for cancer diagnosis and prognosis. Despite these advancements, machine learning models face challenges stemming from limited labeled sample sizes, the intricate interplay of high-dimensionality data types, the inherent heterogeneity observed among patients and within tumors, and concerns about interpretability and consistency with existing biomedical knowledge. One approach to surmount these challenges is to integrate biomedical knowledge into data-driven models, which has proven potential to improve the accuracy, robustness, and interpretability of model results. Here, we review the state-of-the-art machine learning studies that adopted the fusion of biomedical knowledge and data, termed knowledge-informed machine learning, for cancer diagnosis and prognosis. Emphasizing the properties inherent in four primary data types including clinical, imaging, molecular, and treatment data, we highlight modeling considerations relevant to these contexts. We provide an overview of diverse forms of knowledge representation and current strategies of knowledge integration into machine learning pipelines with concrete examples. We conclude the review article by discussing future directions to advance cancer research through knowledge-informed machine learning.Comment: 41 pages, 4 figures, 2 table