3,001,631 research outputs found
Simplified dc to dc converter
A dc to dc converter which can start with a shorted output and which regulates output voltage and current is described. Voltage controlled switches directed current through the primary of a transformer the secondary of which includes virtual reactance. The switching frequency of the switches is appropriately varied to increase the voltage drop across the virtual reactance in the secondary winding to which there is connected a low impedance load. A starting circuit suitable for voltage switching devices is provided
A dc to dc converter
The object of the invention is to provide an improved converter for converting one direct current voltage to another. A plurality of phased square wave voltages are provided from a ring counter through amplifiers to a like plurality of output transformers. Each of these transformers has two windings, and S(1) winding and an S(2) winding. The S(1) windings are connected in series, then the S(2) windings are connected in series, and finally, the two sets of windings are connected in series. One of six SCRs is connected between each two series connected windings to a positive output terminal and one of diodes is connected between each set of two windings of a zero output terminal. By virtue of this configuration, a quite high average direct current voltage is obtained, which varies between full voltage and two-thirds full voltage rather than from full voltage to zero. Further, its variation, ripple frequency, is reduced to one-sixth of that present in a single phase system. Application to raising battery voltage for an ion propulsion system is mentioned
DC fault isolation study of bidirectional dual active bridge DC/DC converter for DC transmission grid application
Fast isolation and detection of DC faults is currently a limiting factor in high power DC transmission grid development. Recent research has shown that the role of DC/DC converters is becoming increasingly important in solving various DC grid challenges such as voltage stepping, galvanic isolation and power regulation. This paper focuses on an additional important feature of bidirectional dual active bridge (DAB) DC-DC converters which make it attractive for future DC grids; it's inherent fault isolation capability which does not need control intervention to limit fault current in case of the most severe DC faults. Detailed analytical, simulation and experimental study are performed by subjecting the converter to DC short circuit faults at its DC voltage terminals. The results obtained have shown significant advantage of DAB where fault current is less than rated current during the fault duration. Thus no control action is necessary from the non-faulted bridge to limit fault current and no external DC circuit breakers are required. This advantage makes DAB converter feasible for DC grid integration
An Efficiency-Focused Design of Direct-DC Loads in Buildings
Despite the recent interest in direct current (DC) power distribution in buildings, the market for DC-ready loads remains small. The existing DC loads in various products or research test beds are not always designed to efficiently leverage the benefits of DC. This work addresses a pressing need for a study into the development of efficient DC loads. In particular, it focuses on documenting and demonstrating how to best leverage a DC input to eliminate or improve conversion stages in a load’s power converter. This work identifies how typical building loads can benefit from DC input, including bath fans, refrigerators, task lights, and zone lighting. It then details the development of several prototypes that demonstrate efficiency savings with DC. The most efficient direct-DC loads are explicitly designed for DC from the ground up, rather than from an AC modification
Efficient LDO-Assisted DC/DC buck converter for integrated power management system
DC-DC Switching Converters; Voltage Linear Regulators; Linear-Assisted DC-DC Voltage Regulators.Postprint (published version
Solid state single-ended switching dc-to-dc converter
Solid state, single-ended switching dc-to-dc converter electrically isolated a dc supply from the prime dc power service
IRX-2, a Novel Immunotherapeutic, Enhances Functions of Human Dendritic Cells
Background: In a recent phase II clinical trial for HNSCC patients, IRX-2, a cell-derived biologic, promoted T-cell infiltration into the tumor and prolonged overall survival. Mechanisms responsible for these IRX-2-mediated effects are unknown. We hypothesized that IRX-2 enhanced tumor antigen-(TA)-specific immunity by up-regulating functions of dendritic cells (DC). Methodology/Principal Findings: Monocyte-derived DC obtained from 18 HNSCC patients and 12 healthy donors were matured using IRX-2 or a mix of TNF-α, IL-1β and IL-6 ("conv. mix"). Multicolor flow cytometry was used to study the DC phenotype and antigen processing machinery (APM) component expression. ELISPOT and cytotoxicity assays were used to evaluate tumor-reactive cytotoxic T lymphocytes (CTL). IL-12p70 and IL-10 production by DC was measured by Luminex® and DC migration toward CCL21 was tested in transwell migration assays. IRX-2-matured DC functions were compared with those of conv. mix-matured DC. IRX-2-matured DC expressed higher levels (p<0.05) of CD11c, CD40, CCR7 as well as LMP2, TAP1, TAP2 and tapasin than conv. mix-matured DC. IRX-2-matured DC migrated significantly better towards CCL21, produced more IL-12p70 and had a higher IL12p70/IL-10 ratio than conv. mix-matured DC (p<0.05 for all). IRX-2-matured DC carried a higher density of tumor antigen-derived peptides, and CTL primed with these DC mediated higher cytotoxicity against tumor targets (p<0.05) compared to the conv. mix-matured DC. Conclusion: Excellent ability of IRX-2 to induce ex vivo DC maturation in HNSCC patients explains, in part, its clinical benefits and emphasizes its utility in ex vivo maturation of DC generated for therapy. © 2013 Schilling et al
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