309 research outputs found

    ICF quarterly report January - March 1997 volume 7, number 3

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    A nano-tensile testing system for studying nanostructures inside an electron microscope:design, characterization and application

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    Mechanical properties of nanostructures could be remarkably different from their bulk counterparts owing to scale effects, which have attracted considerable research interest in recent years. However, nanomechanics studies are hindered by the difficulties of conducting well-instrumented mechanical testing. The objective of this thesis is to develop a novel tensile stage that can be used to probe mechanical properties of universal one-dimensional (1D) nanostructures, like nanowires and nanotubes, inside a scanning/transmission electron microscope (SEM/TEM). The main challenges of performing tensile tests at the nanoscale are: (1) specimen alignment and fixation on the tensile stage; (2) application and measurement of tensile force with nano-Newton resolution; (3) measurement of specimen elongation with nanometer resolution. Previous studies have shown that micro-electromechanical system (MEMS) technology combined with advanced microscopy (e.g. SEM and TEM) provides promising perspectives to address these challenges. Two types of nano-tensile stages, fabricated in a silicon on insulator (SOI) wafer, were developed in this thesis, which consisted of a comb-drive actuator and either a differential capacitive force sensor or a double clamped beam force sensor. The optimized comb-drive actuators could output an in-plane force of about 210 µN at a drive voltage of 120 V, and the force sensors achieved resolutions of better than 50 nN. Individual 1D nanostructures were placed on the MEMS device by in-situ nanomanipulations and fixed at their two ends via focused electron beam induced deposition (FEBID). A strategy of modifying device topography, e.g. in the form of trenches or pillars, was proposed to facilitate the specimen preparation by in-situ manipulation that could achieve a high yield of about 80%. The mechanical testing function of the developed micro devices was demonstrated by tensile tests on individual Co and Si nanowires (NWs) inside an SEM. The average apparent Young's modulus, tensile strength and fracture strain of the electrochemically deposited Co NWs were measured to be (75.3±14.6) GPa, (1.6±0.4) GPa and (2.2±0.6) %, respectively. The measured Young's modulus is significantly lower than that of Co in the bulk form (209 GPa), which is likely caused by structural defects (e.g. pores) and surface effects (e.g. surface contaminations and surface oxide layers). The phosphorous-doped SiNWs grown bottom up by the vapor-liquid-solid (VLS) technique showed an average Young's modulus of (170.0±2.4) GPa and a tensile strength larger than 8.3 GPa. This finding confirms that materials strength increases as their sizes scale down. The top down electroless chemically etched Si NWs show a tensile strength of 5.4 GPa. The developed MEMS devices and experimental techniques enable an alternative way of in-situ nanomechanical characterization based on electron microscopy. The design methodology and learning presented in this thesis would be useful to develop nano-tensile stages of other configurations with more advanced functions

    Modular soft pneumatic actuator system design for compliance matching

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    The future of robotics is personal. Never before has technology been as pervasive as it is today, with advanced mobile electronics hardware and multi-level network connectivity pushing âsmartâ devices deeper into our daily lives through home automation systems, virtual assistants, and wearable activity monitoring. As the suite of personal technology around us continues to grow in this way, augmenting and offloading the burden of routine activities of daily living, the notion that this trend will extend to robotics seems inevitable. Transitioning robots from their current principal domain of industrial factory settings to domestic, workplace, or public environments is not simply a matter of relocation or reprogramming, however. The key differences between âtraditionalâ types of robots and those which would best serve personal, proximal, human interactive applications demand a new approach to their design. Chief among these are requirements for safety, adaptability, reliability, reconfigurability, and to a more practical extent, usability. These properties frame the context and objectives of my thesis work, which seeks to provide solutions and answers to not only how these features might be achieved in personal robotic systems, but as well what benefits they can afford. I approach the investigation of these questions from a perspective of compliance matching of hardware systems to their applications, by providing methods to achieve mechanical attributes complimentary to their environment and end-use. These features are fundamental to the burgeoning field of Soft Robotics, wherein flexible, compliant materials are used as the basis for the structure, actuation, sensing, and control of complete robotic systems. Combined with pressurized air as a power source, soft pneumatic actuator (SPA) based systems offers new and novel methods of exploiting the intrinsic compliance of soft material components in robotic systems. While this strategy seems to answer many of the needs for human-safe robotic applications, it also brings new questions and challenges: What are the needs and applications personal robots may best serve? Are soft pneumatic actuators capable of these tasks, or âusefulâ work output and performance? How can SPA based systems be applied to provide complex functionality needed for operation in diverse, real-world environments? What are the theoretical and practical challenges in implementing scalable, multiple degrees of freedom systems, and how can they be overcome? I present solutions to these problems in my thesis work, elucidated through scientific design, testing and evaluation of robotic prototypes which leverage and demonstrate three key features: 1) Intrinsic compliance: provided by passive elastic and flexible component material properties, 2) Extrinsic compliance: rendered through high number of independent, controllable degrees of freedom, and 3) Complementary design: exhibited by modular, plug and play architectures which combine both attributes to achieve compliant systems. Through these core projects and others listed below I have been engaged in soft robotic technology, its application, and solutions to the challenges which are critical to providing a path forward within the soft robotics field, as well as for the future of personal robotics as a whole toward creating a better society

    Technology 2003: Conference Proceedings from the Fourth National Technology Transfer Conference and Exposition, Volume 1

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    Proceedings from symposia of the Technology 2003 Conference and Exposition, December 7-9, I993, Anaheim, CA. Volume 1 features the Plenary Session and the Plenary Workshop, plus papers presented in Advanced Manufacturing, Biotechnology/Medical Technology, Environmental Technology, Materials Science, and Power and Energy

    COBE's search for structure in the Big Bang

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    The launch of Cosmic Background Explorer (COBE) and the definition of Earth Observing System (EOS) are two of the major events at NASA-Goddard. The three experiments contained in COBE (Differential Microwave Radiometer (DMR), Far Infrared Absolute Spectrophotometer (FIRAS), and Diffuse Infrared Background Experiment (DIRBE)) are very important in measuring the big bang. DMR measures the isotropy of the cosmic background (direction of the radiation). FIRAS looks at the spectrum over the whole sky, searching for deviations, and DIRBE operates in the infrared part of the spectrum gathering evidence of the earliest galaxy formation. By special techniques, the radiation coming from the solar system will be distinguished from that of extragalactic origin. Unique graphics will be used to represent the temperature of the emitting material. A cosmic event will be modeled of such importance that it will affect cosmological theory for generations to come. EOS will monitor changes in the Earth's geophysics during a whole solar color cycle

    NASA Tech Briefs, January 1995

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    Topics include: Sensors; Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Computer Programs; Mechanics; Machinery; Fabrication Technology; Mathematics and Information Sciences; Life Sciences; Books and Report

    Microfluidics and Nanofluidics Handbook

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    The Microfluidics and Nanofluidics Handbook: Two-Volume Set comprehensively captures the cross-disciplinary breadth of the fields of micro- and nanofluidics, which encompass the biological sciences, chemistry, physics and engineering applications. To fill the knowledge gap between engineering and the basic sciences, the editors pulled together key individuals, well known in their respective areas, to author chapters that help graduate students, scientists, and practicing engineers understand the overall area of microfluidics and nanofluidics. Topics covered include Finite Volume Method for Numerical Simulation Lattice Boltzmann Method and Its Applications in Microfluidics Microparticle and Nanoparticle Manipulation Methane Solubility Enhancement in Water Confined to Nanoscale Pores Volume Two: Fabrication, Implementation, and Applications focuses on topics related to experimental and numerical methods. It also covers fabrication and applications in a variety of areas, from aerospace to biological systems. Reflecting the inherent nature of microfluidics and nanofluidics, the book includes as much interdisciplinary knowledge as possible. It provides the fundamental science background for newcomers and advanced techniques and concepts for experienced researchers and professionals

    Engineering of human cardiac muscle electromechanically matured to an adult-like phenotype

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    Author ManuscriptThe application of tissue-engineering approaches to human induced pluripotent stem (hiPS) cells enables the development of physiologically relevant human tissue models for in vitro studies of development, regeneration, and disease. However, the immature phenotype of hiPS-derived cardiomyocytes (hiPS-CMs) limits their utility. We have developed a protocol to generate engineered cardiac tissues from hiPS cells and electromechanically mature them toward an adult-like phenotype. This protocol also provides optimized methods for analyzing these tissues' functionality, ultrastructure, and cellular properties. The approach relies on biological adaptation of cultured tissues subjected to biomimetic cues, applied at an increasing intensity, to drive accelerated maturation. hiPS cells are differentiated into cardiomyocytes and used immediately after the first contractions are observed, when they still have developmental plasticity. This starting cell population is combined with human dermal fibroblasts, encapsulated in a fibrin hydrogel and allowed to compact under passive tension in a custom-designed bioreactor. After 7 d of tissue formation, the engineered tissues are matured for an additional 21 d by increasingly intense electromechanical stimulation. Tissue properties can be evaluated by measuring contractile function, responsiveness to electrical stimuli, ultrastructure properties (sarcomere length, mitochondrial density, networks of transverse tubules), force-frequency and force-length relationships, calcium handling, and responses to β-adrenergic agonists. Cell properties can be evaluated by monitoring gene/protein expression, oxidative metabolism, and electrophysiology. The protocol takes 4 weeks and requires experience in advanced cell culture and machining methods for bioreactor fabrication. We anticipate that this protocol will improve modeling of cardiac diseases and testing of drugs.NIBIB and NCATS grant EB17103 (G.V.-N.); NIBIB, NCATS, NIAMS, NIDCR, and NIEHS grant EB025765 (G.V.-N.); NHLBI grants HL076485 (G.V.-N.) and HL138486 (M.Y.); NSF grant 16478 (G.V.-N.); the University of Minho MD/PhD program (D.T.); a Japan Society for the Promotion of Science fellowship (K.M.); and the Columbia University Stem Cell Initiative (L.S., M.Y.

    The human role in space. Volume 2: Research analysis and technology report

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    The human role in space was studied. The role and the degree of direct involvement of humans that will be required in future space missions are investigated. Valid criteria for allocating functional activities between humans and machines were established. The technology requirements, economics, and benefits of the human presence in space was examined. Topics discussed include: human qualifications for space activities; specific project assessments; technology requirements and tasks; and generalization on human roles in space
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