Primal-dual splitting algorithm for solving inclusions with mixtures of composite, Lipschitzian, and parallel-sum monotone operators

We propose a primal-dual splitting algorithm for solving monotone inclusions involving a mixture of sums, linear compositions, and parallel sums of set-valued and Lipschitzian operators. An important feature of the algorithm is that the Lipschitzian operators present in the formulation can be processed individually via explicit steps, while the set-valued operators are processed individually via their resolvents. In addition, the algorithm is highly parallel in that most of its steps can be executed simultaneously. This work brings together and notably extends various types of structured monotone inclusion problems and their solution methods. The application to convex minimization problems is given special attention

Modelling fluid deformable surfaces with an emphasis on biological interfaces

Fluid deformable surfaces are ubiquitous in cell and tissue biology, including lipid bilayers, the actomyosin cortex or epithelial cell sheets. These interfaces exhibit a complex interplay between elasticity, low Reynolds number interfacial hydrodynamics, chemistry and geometry, and govern important biological processes such as cellular traffic, division, migration or tissue morphogenesis. To address the modelling challenges posed by this class of problems, in which interfacial phenomena tightly interact with the shape and dynamics of the surface, we develop a general continuum mechanics and computational framework for fluid deformable surfaces. The dual solid–fluid nature of fluid deformable surfaces challenges classical Lagrangian or Eulerian descriptions of deforming bodies. Here, we extend the notion of arbitrarily Lagrangian–Eulerian (ALE) formulations, well-established for bulk media, to deforming surfaces. To systematically develop models for fluid deformable surfaces, which consistently treat all couplings between fields and geometry, we follow a nonlinear Onsager formalism according to which the dynamics minimizes a Rayleighian functional where dissipation, power input and energy release rate compete. Finally, we propose new computational methods, which build on Onsager’s formalism and our ALE formulation, to deal with the resulting stiff system of higher-order partial differential equations. We apply our theoretical and computational methodology to classical models for lipid bilayers and the cell cortex. The methods developed here allow us to formulate/simulate these models in their full three-dimensional generality, accounting for finite curvatures and finite shape changes. This article has been published in a revised form in Journal of fluid mechanics

Modelling fluid deformable surfaces with an emphasis on biological interfaces

This article has been published in a revised form in Journal of fluid mechanics, http://dx.doi.org/10.1017/jfm.2019.341. This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © 2019Fluid deformable surfaces are ubiquitous in cell and tissue biology, including lipid bilayers, the actomyosin cortex or epithelial cell sheets. These interfaces exhibit a complex interplay between elasticity, low Reynolds number interfacial hydrodynamics, chemistry and geometry, and govern important biological processes such as cellular traffic, division, migration or tissue morphogenesis. To address the modelling challenges posed by this class of problems, in which interfacial phenomena tightly interact with the shape and dynamics of the surface, we develop a general continuum mechanics and computational framework for fluid deformable surfaces. The dual solid–fluid nature of fluid deformable surfaces challenges classical Lagrangian or Eulerian descriptions of deforming bodies. Here, we extend the notion of arbitrarily Lagrangian–Eulerian (ALE) formulations, well-established for bulk media, to deforming surfaces. To systematically develop models for fluid deformable surfaces, which consistently treat all couplings between fields and geometry, we follow a nonlinear Onsager formalism according to which the dynamics minimizes a Rayleighian functional where dissipation, power input and energy release rate compete. Finally, we propose new computational methods, which build on Onsager’s formalism and our ALE formulation, to deal with the resulting stiff system of higher-order partial differential equations. We apply our theoretical and computational methodology to classical models for lipid bilayers and the cell cortex. The methods developed here allow us to formulate/simulate these models in their full three-dimensional generality, accounting for finite curvatures and finite shape changes.Peer ReviewedPostprint (author's final draft

The Geometry of Monotone Operator Splitting Methods

We propose a geometric framework to describe and analyze a wide array of operator splitting methods for solving monotone inclusion problems. The initial inclusion problem, which typically involves several operators combined through monotonicity-preserving operations, is seldom solvable in its original form. We embed it in an auxiliary space, where it is associated with a surrogate monotone inclusion problem with a more tractable structure and which allows for easy recovery of solutions to the initial problem. The surrogate problem is solved by successive projections onto half-spaces containing its solution set. The outer approximation half-spaces are constructed by using the individual operators present in the model separately. This geometric framework is shown to encompass traditional methods as well as state-of-the-art asynchronous block-iterative algorithms, and its flexible structure provides a pattern to design new ones

Microstructures in Solids: From Quantum Models to Continua

The mathematical theory of solids was studied from the modern perspective of materials with microcstructures. The discussed topics ranged from experimental findings, via numerical simulations and mathematical modeling to the analysis of models with microstructures. A special emphasis was given to theories providing rigorous insight into and justification of the limit passage between different scales

Variational Methods for Evolution

The meeting focused on the last advances in the applications of variational methods to evolution problems governed by partial differential equations. The talks covered a broad range of topics, including large deviation and variational principles, rate-independent evolutions and gradient flows, heat flows in metric-measure spaces, propagation of fracture, applications of optimal transport and entropy-entropy dissipation methods, phase-transitions, viscous approximation, and singular-perturbation problems