Good government, governance, human complexity

Studi n. 50- Indice del volume #7- Part one. The Einaudian legacy: good government and the relation between private and public #21- Part two. Good government and public governance #119- Part three. Governance and liberty: the complexity of the human #22

Equal-Volume Strength Training With Different Training Frequencies Induces Similar Muscle Hypertrophy and Strength Improvement in Trained Participants

The main goal of the current study was to compare the effects of volume-equated training frequency on gains in muscle mass and strength. In addition, we aimed to investigate whether the effect of training frequency was affected by the complexity, concerning the degrees of freedom, of an exercise. Participants were randomized to a moderate training frequency group (two weekly sessions) or high training frequency group (four weekly sessions). Twenty-one participants (male: 11, female: 10, age: 25.9 ± 4.0) completed the 9-week whole-body progressive heavy resistance training intervention with moderate (n = 13) or high (n = 8) training frequency. Whole-body and regional changes in lean mass were measured using dual-energy x-ray absorptiometry, while the vastus lateralis thickness was measured by ultrasound. Changes in muscle strength were measured as one repetition maximum for squat, hack squat, bench press, and chest press. No differences between groups were observed for any of the measures of muscle growth or muscle strength. Muscle strength increased to a greater extent in hack squat and chest press than squat and bench press for both moderate (50 and 21% vs. 19 and 14%, respectively) and high-frequency groups (63 and 31% vs. 19 and 16%, respectively), with no differences between groups. These results suggest that training frequency is less decisive when weekly training volume is equated. Further, familiarity with an exercise seems to be of greater importance for strength adaptations than the complexity of the exercise.publishedVersio

Positivity of the universal pairing in 3 dimensions

Associated to a closed, oriented surface S is the complex vector space with basis the set of all compact, oriented 3-manifolds which it bounds. Gluing along S defines a Hermitian pairing on this space with values in the complex vector space with basis all closed, oriented 3-manifolds. The main result in this paper is that this pairing is positive, i.e. that the result of pairing a nonzero vector with itself is nonzero. This has bearing on the question of what kinds of topological information can be extracted in principle from unitary 2+1 dimensional TQFTs. The proof involves the construction of a suitable complexity function c on all closed 3-manifolds, satisfying a gluing axiom which we call the topological Cauchy-Schwarz inequality, namely that c(AB) <= max(c(AA),c(BB)) for all A,B which bound S, with equality if and only if A=B. The complexity function c involves input from many aspects of 3-manifold topology, and in the process of establishing its key properties we obtain a number of results of independent interest. For example, we show that when two finite volume hyperbolic 3-manifolds are glued along an incompressible acylindrical surface, the resulting hyperbolic 3-manifold has minimal volume only when the gluing can be done along a totally geodesic surface; this generalizes a similar theorem for closed hyperbolic 3-manifolds due to Agol-Storm-Thurston.Comment: 83 pages, 21 figures; version 3: incorporates referee's comments and correction

Holographic local quench and effective complexity

We study the evolution of holographic complexity of pure and mixed states in $1+1$-dimensional conformal field theory following a local quench using both the "complexity equals volume" (CV) and the "complexity equals action" (CA) conjectures. We compare the complexity evolution to the evolution of entanglement entropy and entanglement density, discuss the Lloyd computational bound and demonstrate its saturation in certain regimes. We argue that the conjectured holographic complexities exhibit some non-trivial features indicating that they capture important properties of what is expected to be effective (or physical) complexity.Comment: 33 pages, 19 figures; v2: typos corrected; 35 pages, references added, new appendix. Version to match published in JHE

A Growing Journey From Neurotrophins To Metabotrophins In Cardiometabolic Diseases

Currently, obesity has been recognized as a prime risk in the development of car-diometabolic diseases (CMD) and neurodegenerative diseases (NDD). The patho-genesis and therapy of CMD are immensely complex at the cellular and molecular levels. This scenario raises the question of how such a complexity may be grappled in a more tangible manner. Since 2003, we have been thinking “what nobody has yet thought about that everybody sees”, namely, matabotrophic factors (MTF, metabotrophins). The latter include mainly (i) the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), and (ii) the adipomyo-kines adiponectin, irisin, BDNF, fibroblast growth factor-21 alike as adipose- and skeletal muscle-derived signaling proteins (these latter discussed in another review in the present volume of Adipobiology). Herein, we argue that obesity and related CMD and NDD, particularly Alzheimer’s disease, may be viewed as MTF-deficient diseases. Further studies on MTF signatures and ramifications in these diseases are required. These would provide greater insights on how we can make MTF work for the improvement of physiological and psychological quality of human life

On the Noether charge and the gravity duals of quantum complexity

The physical relevance of the thermodynamic volumes of AdS black holes to the gravity duals of quantum complexity was recently argued by Couch et al. In this paper, by generalizing the Wald-Iyer formalism, we derive a geometric expression for the thermodynamic volume and relate its product with the thermodynamic pressure to the non-derivative part of the gravitational action evaluated on the Wheeler-DeWitt patch. We propose that this action provides an alternative gravity dual of the quantum complexity of the boundary theory. We refer this to "complexity=action 2.0" (CA-2) duality. It is significantly different from the original "complexity=action" (CA) duality as well as the "complexity=volume 2.0" (CV-2) duality proposed by Couch et al. The latter postulates that the complexity is dual to the spacetime volume of the Wheeler-DeWitt patch. To distinguish our new conjecture from the various dualities in literature, we study a number of black holes in Einstein-Maxwell-Dilation theories. We find that for all these black holes, the CA duality generally does not respect the Lloyd bound whereas the CV-2 duality always does. For the CA-2 duality, although in many cases it is consistent with the Lloyd bound, we also find a counter example for which it violates the bound as well.Comment: minor corrections, references added,29pages,7figure