Algorithmic patterns for H\mathcal{H}-matrices on many-core processors

In this work, we consider the reformulation of hierarchical ($\mathcal{H}$) matrix algorithms for many-core processors with a model implementation on graphics processing units (GPUs). $\mathcal{H}$ matrices approximate specific dense matrices, e.g., from discretized integral equations or kernel ridge regression, leading to log-linear time complexity in dense matrix-vector products. The parallelization of $\mathcal{H}$ matrix operations on many-core processors is difficult due to the complex nature of the underlying algorithms. While previous algorithmic advances for many-core hardware focused on accelerating existing $\mathcal{H}$ matrix CPU implementations by many-core processors, we here aim at totally relying on that processor type. As main contribution, we introduce the necessary parallel algorithmic patterns allowing to map the full $\mathcal{H}$ matrix construction and the fast matrix-vector product to many-core hardware. Here, crucial ingredients are space filling curves, parallel tree traversal and batching of linear algebra operations. The resulting model GPU implementation hmglib is the, to the best of the authors knowledge, first entirely GPU-based Open Source $\mathcal{H}$ matrix library of this kind. We conclude this work by an in-depth performance analysis and a comparative performance study against a standard $\mathcal{H}$ matrix library, highlighting profound speedups of our many-core parallel approach

BioWorkbench: A High-Performance Framework for Managing and Analyzing Bioinformatics Experiments

Advances in sequencing techniques have led to exponential growth in biological data, demanding the development of large-scale bioinformatics experiments. Because these experiments are computation- and data-intensive, they require high-performance computing (HPC) techniques and can benefit from specialized technologies such as Scientific Workflow Management Systems (SWfMS) and databases. In this work, we present BioWorkbench, a framework for managing and analyzing bioinformatics experiments. This framework automatically collects provenance data, including both performance data from workflow execution and data from the scientific domain of the workflow application. Provenance data can be analyzed through a web application that abstracts a set of queries to the provenance database, simplifying access to provenance information. We evaluate BioWorkbench using three case studies: SwiftPhylo, a phylogenetic tree assembly workflow; SwiftGECKO, a comparative genomics workflow; and RASflow, a RASopathy analysis workflow. We analyze each workflow from both computational and scientific domain perspectives, by using queries to a provenance and annotation database. Some of these queries are available as a pre-built feature of the BioWorkbench web application. Through the provenance data, we show that the framework is scalable and achieves high-performance, reducing up to 98% of the case studies execution time. We also show how the application of machine learning techniques can enrich the analysis process

An Evolutionary Algorithm to Optimize Log/Restore Operations within Optimistic Simulation Platforms

In this work we address state recoverability in advanced optimistic simulation systems by proposing an evolutionary algorithm to optimize at run-time the parameters associated with state log/restore activities. Optimization takes place by adaptively selecting for each simulation object both (i) the best suited log mode (incremental vs non-incremental) and (ii) the corresponding optimal value of the log interval. Our performance optimization approach allows to indirectly cope with hidden effects (e.g., locality) as well as cross-object effects due to the variation of log/restore parameters for different simulation objects (e.g., rollback thrashing). Both of them are not captured by literature solutions based on analytical models of the overhead associated with log/restore tasks. More in detail, our evolutionary algorithm dynamically adjusts the log/restore parameters of distinct simulation objects as a whole, towards a well suited configuration. In such a way, we prevent negative effects on performance due to the biasing of the optimization towards individual simulation objects, which may cause reduced gains (or even decrease) in performance just due to the aforementioned hidden and/or cross-object phenomena. We also present an application-transparent implementation of the evolutionary algorithm within the ROme OpTimistic Simulator (ROOT-Sim), namely an open source, general purpose simulation environment designed according to the optimistic synchronization paradigm