Low Power Circuits for Smart Flexible ECG Sensors

Cardiovascular diseases (CVDs) are the world leading cause of death. In-home heart condition monitoring effectively reduced the CVD patient hospitalization rate. Flexible electrocardiogram (ECG) sensor provides an affordable, convenient and comfortable in-home monitoring solution. The three critical building blocks of the ECG sensor i.e., analog frontend (AFE), QRS detector, and cardiac arrhythmia classifier (CAC), are studied in this research. A fully differential difference amplifier (FDDA) based AFE that employs DC-coupled input stage increases the input impedance and improves CMRR. A parasitic capacitor reuse technique is proposed to improve the noise/area efficiency and CMRR. An on-body DC bias scheme is introduced to deal with the input DC offset. Implemented in 0.35m CMOS process with an area of 0.405mm2, the proposed AFE consumes 0.9W at 1.8V and shows excellent noise effective factor of 2.55, and CMRR of 76dB. Experiment shows the proposed AFE not only picks up clean ECG signal with electrodes placed as close as 2cm under both resting and walking conditions, but also obtains the distinct -wave after eye blink from EEG recording. A personalized QRS detection algorithm is proposed to achieve an average positive prediction rate of 99.39% and sensitivity rate of 99.21%. The user-specific template avoids the complicate models and parameters used in existing algorithms while covers most situations for practical applications. The detection is based on the comparison of the correlation coefficient of the user-specific template with the ECG segment under detection. The proposed one-target clustering reduced the required loops. A continuous-in-time discrete-in-amplitude (CTDA) artificial neural network (ANN) based CAC is proposed for the smart ECG sensor. The proposed CAC achieves over 98% classification accuracy for 4 types of beats defined by AAMI (Association for the Advancement of Medical Instrumentation). The CTDA scheme significantly reduces the input sample numbers and simplifies the sample representation to one bit. Thus, the number of arithmetic operations and the ANN structure are greatly simplified. The proposed CAC is verified by FPGA and implemented in 0.18m CMOS process. Simulation results show it can operate at clock frequencies from 10KHz to 50MHz. Average power for the patient with 75bpm heart rate is 13.34W

Efficient audio signal processing for embedded systems

We investigated two design strategies that would allow us to efficiently process audio signals on embedded systems such as mobile phones and portable electronics. In the first strategy, we exploit properties of the human auditory system to process audio signals. We designed a sound enhancement algorithm to make piezoelectric loudspeakers sound "richer" and "fuller," using a combination of bass extension and dynamic range compression. We also developed an audio energy reduction algorithm for loudspeaker power management by suppressing signal energy below the masking threshold. In the second strategy, we use low-power analog circuits to process the signal before digitizing it. We designed an analog front-end for sound detection and implemented it on a field programmable analog array (FPAA). The sound classifier front-end can be used in a wide range of applications because programmable floating-gate transistors are employed to store classifier weights. Moreover, we incorporated a feature selection algorithm to simplify the analog front-end. A machine learning algorithm AdaBoost is used to select the most relevant features for a particular sound detection application. We also designed the circuits to implement the AdaBoost-based analog classifier.PhDCommittee Chair: Anderson, David; Committee Member: Hasler, Jennifer; Committee Member: Hunt, William; Committee Member: Lanterman, Aaron; Committee Member: Minch, Bradle

Implementation of a neural network-based electromyographic control system for a printed robotic hand

3D printing has revolutionized the manufacturing process reducing costs and time, but only when combined with robotics and electronics, this structures could develop their full potential. In order to improve the available printable hand designs, a control system based on electromyographic (EMG) signals has been implemented, so that different movement patterns can be recognized and replicated in the bionic hand in real time. This control system has been developed in Matlab/ Simulink comprising EMG signal acquisition, feature extraction, dimensionality reduction and pattern recognition through a trained neural-network. Pattern recognition depends on the features used, their dimensions and the time spent in signal processing. Finding balance between this execution time and the input features of the neural network is a crucial step for an optimal classification.Ingeniería Biomédic

Unsupervised Heart-rate Estimation in Wearables With Liquid States and A Probabilistic Readout

Heart-rate estimation is a fundamental feature of modern wearable devices. In this paper we propose a machine intelligent approach for heart-rate estimation from electrocardiogram (ECG) data collected using wearable devices. The novelty of our approach lies in (1) encoding spatio-temporal properties of ECG signals directly into spike train and using this to excite recurrently connected spiking neurons in a Liquid State Machine computation model; (2) a novel learning algorithm; and (3) an intelligently designed unsupervised readout based on Fuzzy c-Means clustering of spike responses from a subset of neurons (Liquid states), selected using particle swarm optimization. Our approach differs from existing works by learning directly from ECG signals (allowing personalization), without requiring costly data annotations. Additionally, our approach can be easily implemented on state-of-the-art spiking-based neuromorphic systems, offering high accuracy, yet significantly low energy footprint, leading to an extended battery life of wearable devices. We validated our approach with CARLsim, a GPU accelerated spiking neural network simulator modeling Izhikevich spiking neurons with Spike Timing Dependent Plasticity (STDP) and homeostatic scaling. A range of subjects are considered from in-house clinical trials and public ECG databases. Results show high accuracy and low energy footprint in heart-rate estimation across subjects with and without cardiac irregularities, signifying the strong potential of this approach to be integrated in future wearable devices.Comment: 51 pages, 12 figures, 6 tables, 95 references. Under submission at Elsevier Neural Network

An ultra-low power in-memory computing cell for binarized neural networks

Deep Neural Networks (DNN’s) are widely used in many artificial intelligence applications such as image classification and image recognition. Data movement in DNN’s results in increased power consumption. The primary reason behind the energy-expensive data movement in DNN’s is due to the conventional Von Neuman architecture in which computing unit and memory are physically separated. To address the issue of energy-expensive data movement in DNN’s in-memory computing schemes are proposed in the literature. The fundamental principle behind in-memory computing is to enable the vector computations closer to the memory. In-memory computing schemes based on CMOS technologies are of great importance nowadays due to the ease of massive production and commercialization. However, many of the proposed in-memory computing schemes suffer from power and performance degradation. Besides, some of them are capable of reducing power consumption only to a small extent and this requires sacrificing the overall signal to noise ratio (SNR). This thesis discusses an efficient In-Memory Computing (IMC) cell for Binarized Neural Networks (BNNs). Moreover, IMC cell was modelled using the simplest current computing method. In this thesis, the developed IMC cell is a practical solution to the energy-expensive data movement within the BNNs. A 4-bit Digital to Analog Converter (DAC) is designed and simulated using 130nm CMOS process. Using the 4-bit DAC the functionality of IMC scheme for BNNs is demonstrated. The optimised 4-bit DAC shows that it is a powerful IMC method for BNNs. The results presented in this thesis show this approach of IMC is capable of accurately performing dot operation between the input activations and the weights. Furthermore, 4-bit DAC provides a 4-bit weight precision, which provides an effective means to improve the overall accuracy