Building a semantically annotated corpus of clinical texts

In this paper, we describe the construction of a semantically annotated corpus of clinical texts for use in the development and evaluation of systems for automatically extracting clinically significant information from the textual component of patient records. The paper details the sampling of textual material from a collection of 20,000 cancer patient records, the development of a semantic annotation scheme, the annotation methodology, the distribution of annotations in the final corpus, and the use of the corpus for development of an adaptive information extraction system. The resulting corpus is the most richly semantically annotated resource for clinical text processing built to date, whose value has been demonstrated through its use in developing an effective information extraction system. The detailed presentation of our corpus construction and annotation methodology will be of value to others seeking to build high-quality semantically annotated corpora in biomedical domains

Formative evaluation of a patient-specific clinical knowledge summarization tool

To iteratively design a prototype of a computerized clinical knowledge summarization (CKS) tool aimed at helping clinicians finding answers to their clinical questions; and to conduct a formative assessment of the usability, usefulness, efficiency, and impact of the CKS prototype on physicians’ perceived decision quality compared with standard search of UpToDate and PubMed

Communicative participation improves following motor speech program treatment in apraxia of speech

Childhood apraxia of speech (CAS) is a motor speech disorder characterized by increase in segment and intersegment durations (segmentation), equal stress over words and/or sentences, dysprosody, and speech sound distortions. With decreased intelligibility, limited or lack communicative participation arises from an inability to be understood or lack of confidence in their speech. Establishing communicative participation measurements is integral to generalizing and establishing efficacy of treatment program progress to a child’s everyday life. This study observes the communicative participation change of a group of children (n=6) with idiopathic CAS, receiving a new four-week, 16-hour treatment called Treatment for Establishing Motor Programming Organization (TEMPO). Clinically significant changes were seen in communicative participation post TEMPO treatment using the FOCUS-34© parental questionnaire with an average change of 50 points. Specifically, sub-scales of intelligibility, social/play, independence, and coping/emotional skills were seen as driving components of this change