A Novel Synergistic Model Fusing Electroencephalography and Functional Magnetic Resonance Imaging for Modeling Brain Activities

Study of the human brain is an important and very active area of research. Unraveling the way the human brain works would allow us to better understand, predict and prevent brain related diseases that affect a significant part of the population. Studying the brain response to certain input stimuli can help us determine the involved brain areas and understand the mechanisms that characterize behavioral and psychological traits. In this research work two methods used for the monitoring of brain activities, Electroencephalography (EEG) and functional Magnetic Resonance (fMRI) have been studied for their fusion, in an attempt to bridge together the advantages of each one. In particular, this work has focused in the analysis of a specific type of EEG and fMRI recordings that are related to certain events and capture the brain response under specific experimental conditions. Using spatial features of the EEG we can describe the temporal evolution of the electrical field recorded in the scalp of the head. This work introduces the use of Hidden Markov Models (HMM) for modeling the EEG dynamics. This novel approach is applied for the discrimination of normal and progressive Mild Cognitive Impairment patients with significant results. EEG alone is not able to provide the spatial localization needed to uncover and understand the neural mechanisms and processes of the human brain. Functional Magnetic Resonance imaging (fMRI) provides the means of localizing functional activity, without though, providing the timing details of these activations. Although, at first glance it is apparent that the strengths of these two modalities, EEG and fMRI, complement each other, the fusion of information provided from each one is a challenging task. A novel methodology for fusing EEG spatiotemporal features and fMRI features, based on Canonical Partial Least Squares (CPLS) is presented in this work. A HMM modeling approach is used in order to derive a novel feature-based representation of the EEG signal that characterizes the topographic information of the EEG. We use the HMM model in order to project the EEG data in the Fisher score space and use the Fisher score to describe the dynamics of the EEG topography sequence. The correspondence between this new feature and the fMRI is studied using CPLS. This methodology is applied for extracting features for the classification of a visual task. The results indicate that the proposed methodology is able to capture task related activations that can be used for the classification of mental tasks. Extensions on the proposed models are examined along with future research directions and applications

mARC: Memory by Association and Reinforcement of Contexts

This paper introduces the memory by Association and Reinforcement of Contexts (mARC). mARC is a novel data modeling technology rooted in the second quantization formulation of quantum mechanics. It is an all-purpose incremental and unsupervised data storage and retrieval system which can be applied to all types of signal or data, structured or unstructured, textual or not. mARC can be applied to a wide range of information clas-sification and retrieval problems like e-Discovery or contextual navigation. It can also for-mulated in the artificial life framework a.k.a Conway "Game Of Life" Theory. In contrast to Conway approach, the objects evolve in a massively multidimensional space. In order to start evaluating the potential of mARC we have built a mARC-based Internet search en-gine demonstrator with contextual functionality. We compare the behavior of the mARC demonstrator with Google search both in terms of performance and relevance. In the study we find that the mARC search engine demonstrator outperforms Google search by an order of magnitude in response time while providing more relevant results for some classes of queries

Profile hidden Markov models for foreground object modelling

Accurate background/foreground segmentation is a preliminary process essential to most visual surveillance applications. With the increasing use of freely moving cameras, strategies have been proposed to refine initial segmentation. In this paper, it is proposed to exploit the Vide-omics paradigm, and Profile Hidden Markov Models in particular, to create a new type of object descriptors relying on spatiotemporal information. Performance of the proposed methodology has been evaluated using a standard dataset of videos captured by moving cameras. Results show that usage of the proposed object descriptors allows better foreground extraction than standard approaches

Ensemble learning method for hidden markov models.

For complex classification systems, data are gathered from various sources and potentially have different representations. Thus, data may have large intra-class variations. In fact, modeling each data class with a single model might lead to poor generalization. The classification error can be more severe for temporal data where each sample is represented by a sequence of observations. Thus, there is a need for building a classification system that takes into account the variations within each class in the data. This dissertation introduces an ensemble learning method for temporal data that uses a mixture of Hidden Markov Model (HMM) classifiers. We hypothesize that the data are generated by K models, each of which reacts a particular trend in the data. Model identification could be achieved through clustering in the feature space or in the parameters space. However, this approach is inappropriate in the context of sequential data. The proposed approach is based on clustering in the log-likelihood space, and has two main steps. First, one HMM is fit to each of the N individual sequences. For each fitted model, we evaluate the log-likelihood of each sequence. This will result in an N-by-N log-likelihood distance matrix that will be partitioned into K groups using a relational clustering algorithm. In the second step, we learn the parameters of one HMM per group. We propose using and optimizing various training approaches for the different K groups depending on their size and homogeneity. In particular, we investigate the maximum likelihood (ML), the minimum classification error (MCE) based discriminative, and the Variational Bayesian (VB) training approaches. Finally, to test a new sequence, its likelihood is computed in all the models and a final confidence value is assigned by combining the multiple models outputs using a decision level fusion method such as an artificial neural network or a hierarchical mixture of experts. Our approach was evaluated on two real-world applications: (1) identification of Cardio-Pulmonary Resuscitation (CPR) scenes in video simulating medical crises; and (2) landmine detection using Ground Penetrating Radar (GPR). Results on both applications show that the proposed method can identify meaningful and coherent HMM mixture components that describe different properties of the data. Each HMM mixture component models a group of data that share common attributes. The results indicate that the proposed method outperforms the baseline HMM that uses one model for each class in the data

ToyArchitecture: Unsupervised Learning of Interpretable Models of the World

Research in Artificial Intelligence (AI) has focused mostly on two extremes: either on small improvements in narrow AI domains, or on universal theoretical frameworks which are usually uncomputable, incompatible with theories of biological intelligence, or lack practical implementations. The goal of this work is to combine the main advantages of the two: to follow a big picture view, while providing a particular theory and its implementation. In contrast with purely theoretical approaches, the resulting architecture should be usable in realistic settings, but also form the core of a framework containing all the basic mechanisms, into which it should be easier to integrate additional required functionality. In this paper, we present a novel, purposely simple, and interpretable hierarchical architecture which combines multiple different mechanisms into one system: unsupervised learning of a model of the world, learning the influence of one's own actions on the world, model-based reinforcement learning, hierarchical planning and plan execution, and symbolic/sub-symbolic integration in general. The learned model is stored in the form of hierarchical representations with the following properties: 1) they are increasingly more abstract, but can retain details when needed, and 2) they are easy to manipulate in their local and symbolic-like form, thus also allowing one to observe the learning process at each level of abstraction. On all levels of the system, the representation of the data can be interpreted in both a symbolic and a sub-symbolic manner. This enables the architecture to learn efficiently using sub-symbolic methods and to employ symbolic inference.Comment: Revision: changed the pdftitl