DeltaImpactFinder: Assessing Semantic Merge Conflicts with Dependency Analysis

In software development, version control systems (VCS) provide branching and merging support tools. Such tools are popular among developers to concurrently change a code-base in separate lines and reconcile their changes automatically afterwards. However, two changes that are correct independently can introduce bugs when merged together. We call semantic merge conflicts this kind of bugs. Change impact analysis (CIA) aims at estimating the effects of a change in a codebase. In this paper, we propose to detect semantic merge conflicts using CIA. On a merge, DELTAIMPACTFINDER analyzes and compares the impact of a change in its origin and destination branches. We call the difference between these two impacts the delta-impact. If the delta-impact is empty, then there is no indicator of a semantic merge conflict and the merge can continue automatically. Otherwise, the delta-impact contains what are the sources of possible conflicts.Comment: International Workshop on Smalltalk Technologies 2015, Jul 2015, Brescia, Ital

Fidelity of SNP array genotyping using Epstein Barr virus-transformed B-lymphocyte cell lines: Implications for genome-wide association studies

Background: As availability of primary cells can be limited for genetic studies of human disease, lymphoblastoid cell lines (LCL) are common sources of genomic DNA. LCL are created in a transformation process that entails in vitro infection of human B-lymphocytes with the Epstein-Barr Virus (EBV). Methodology/Principal Findings: To test for genotypic errors potentially induced by the Epstein-Barr Virus transformation process, we compared single nucleotide polymorphism (SNP) genotype calls in peripheral blood mononuclear cells (PBMC) and LCL from the same individuals. The average mismatch rate across 19 comparisons was 0.12% for SNPs with a population call rate of at least 95%, and 0.03% at SNPs with a call rate of at least 99%. Mismatch rates were not correlated across genotype subarrays run on all sample pairs. Conclusions/Significance: Genotypic discrepancies found in PBMC and LCL pairs were not significantly different than control pairs, and were not correlated across subarrays. These results suggest that mismatch rates are minimal with stringent quality control, and that most genotypic discrepancies are due to technical artifacts rather than the EBV transformation process. Thus, LCL likely constitute a reliable DNA source for host genotype analysis. © 2009 Herbeck et al

Controlling motile disclinations in a thick nematogenic material with an electric field

Manipulating topological disclination networks that arise in a symmetry-breaking phase transfor- mation in widely varied systems including anisotropic materials can potentially lead to the design of novel materials like conductive microwires, self-assembled resonators, and active anisotropic matter. However, progress in this direction is hindered by a lack of control of the kinetics and microstructure due to inherent complexity arising from competing energy and topology. We have studied thermal and electrokinetic effects on disclinations in a three-dimensional nonabsorbing nematic material with a positive and negative sign of the dielectric anisotropy. The electric flux lines are highly non-uniform in uniaxial media after an electric field below the Fr\'eedericksz threshold is switched on, and the kinetics of the disclination lines is slowed down. In biaxial media, depending on the sign of the dielectric anisotropy, apart from the slowing down of the disclination kinetics, a non-uniform electric field filters out disclinations of different topology by inducing a kinetic asymmetry. These results enhance the current understanding of forced disclination networks and establish the pre- sented method, which we call fluctuating electronematics, as a potentially useful tool for designing materials with novel properties in silico.Comment: 17 Pages, 14 Figure

Health Secur

Telephone nurse triage lines, such as the Centers for Disease Control and Prevention's (CDC) Flu on Call|, a national nurse triage line, may help reduce the surge in demand for health care during an influenza pandemic by triaging callers, providing advice about clinical care and information about the pandemic, and providing access to prescription antiviral medication. We developed a Call Volume Projection Tool to estimate national call volume to Flu on Call| during an influenza pandemic. The tool incorporates 2 influenza clinical attack rates (20% and 30%), 4 different levels of pandemic severity, and different initial "seed numbers" of cases (10 or 100), and it allows variation in which week the nurse triage line opens. The tool calculates call volume by using call-to-hospitalization ratios based on pandemic severity. We derived data on nurse triage line calls and call-to-hospitalization ratios from experience with the 2009 Minnesota FluLine nurse triage line. Assuming a 20% clinical attack rate and a case hospitalization rate of 0.8% to 1.5% (1968-like pandemic severity), we estimated the nationwide number of calls during the peak week of the pandemic to range from 1,551,882 to 3,523,902. Assuming a more severe 1957-like pandemic (case hospitalization rate\u2009=\u20091.5% to 3.0%), the national number of calls during the peak week of the pandemic ranged from 2,909,778 to 7,047,804. These results will aid in planning and developing nurse triage lines at both the national and state levels for use during a future influenza pandemic.CC999999/Intramural CDC HHS/United States2019-08-23T00:00:00Z30339099PMC67070726585vault:3378

Beyond task-space exploration: On the role of variance for motor control and learning.

This conceptual analysis on the role of variance for motor control and learning should be taken as a call to: (a) overcome the classic motor-action controversy by identifying converging lines and mutual synergies in the explanation of motor behavior phenomena, and (b) design more empirical research on low-level operational aspects of motor behavior rather than on high-level theoretical terms. Throughout the paper, claim (a) is exemplified by deploying the well-accepted task-space landscape metaphor. This approach provides an illustration not only of a dynamical sensorimotor system but also of a structure of internal forward models, as they are used in more cognitively rooted frameworks such as the theory of optimal feedback control. Claim (b) is put into practice by, mainly theoretically, substantiating a number of predictions for the role of variance in motor control and learning that can be derived from a convergent perspective. From this standpoint, it becomes obvious that variance is neither generally "good" nor generally "bad" for sensorimotor learning. Rather, the predictions derived suggest that specific forms of variance cause specific changes on permanent performance. In this endeavor, Newell's concept of task-space exploration is identified as a fundamental learning mechanism. Beyond, we highlight further predictions regarding the optimal use of variance for learning from a converging view. These predictions regard, on the one hand, additional learning mechanisms based on the task-space landscape metaphor-namely task-space formation, task-space differentiation and task-space (de-)composition-and, on the other hand, mechanisms of meta-learning that refer to handling noise as well as learning-to-learn and learning-to-adapt. Due to the character of a conceptual-analysis paper, we grant ourselves the right to be highly speculative on some issues. Thus, we would like readers to see our call mainly as an effort to stimulate both a meta-theoretical discussion on chances for convergence between classically separated lines of thought and, on an empirical level, future research on the role of variance in motor control and learning

An intelligent control system for die casting processes.

The objective of this thesis is to design an intelligent control system for die casting processes involving cooling of a die with multiple channels. The work consists of two parks. First, a correlation between die insert temperature and cooling water outlet temperature is established, which can be used to deduce local die surface temperatures without destructively inserting thermal sensors into a die from its back. Second, a new on-line thermal management scheme is proposed based on an intelligent real-time monitoring and control system (IRMCS) developed for a die insert containing multiple cooling channels. In this scheme, extra cooling water lines controlled by a pump and solenoid valves are hooked up to each established cooling channel. The system is capable of monitoring temperature signals from the die insert and flow rate signals from the cooling lines on the basis of its built-in control algorithms. Pump and solenoid valves can be actuated either automatically or manually to introduce additional cooling water to the die insert for preventing die overheating. (Abstract shortened by UMI.)Dept. of Electrical and Computer Engineering. Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis2005 .Y365. Source: Masters Abstracts International, Volume: 44-03, page: 1469. Thesis (M.A.Sc.)--University of Windsor (Canada), 2005

'IISR Thevam', 'IISR Malabar Excel' and 'IISR Girimunda'- three new black pepper (Piper nigrum L.) clones

Based on 7 years' performance at Valparai (Tamil Nadu) (3000 ft MSL), and 2 years' performance at Peruvannamuzhi (Kerala) and quality evaluation, three black pepper lines namely, Call. 1041, HP-813 and HP-I05 were superior and proposed for release as 'IISR Thevam', 'IISR Malabar Excel' and 'IISR Girimunda', respectively. These lines were superior to at least one of the controls for more than one character at one or both the locations. Trials laid out at farmers' fields in four northern districts of Kerala also indicated the superiority of these lines. Call. 1041 besides out-yielding control, exhibited a high degree of field tolerance to foot rot disease, whereas HP-813 had oleoresin content as high as 12%. &nbsp