Modeling and Mathematical Analysis of Swarms of Microscopic Robots

The biologically-inspired swarm paradigm is being used to design self-organizing systems of locally interacting artificial agents. A major difficulty in designing swarms with desired characteristics is understanding the causal relation between individual agent and collective behaviors. Mathematical analysis of swarm dynamics can address this difficulty to gain insight into system design. This paper proposes a framework for mathematical modeling of swarms of microscopic robots that may one day be useful in medical applications. While such devices do not yet exist, the modeling approach can be helpful in identifying various design trade-offs for the robots and be a useful guide for their eventual fabrication. Specifically, we examine microscopic robots that reside in a fluid, for example, a bloodstream, and are able to detect and respond to different chemicals. We present the general mathematical model of a scenario in which robots locate a chemical source. We solve the scenario in one-dimension and show how results can be used to evaluate certain design decisions.Comment: 2005 IEEE Swarm Intelligence Symposium, Pasadena, CA June 200

Collaborative Deep Reinforcement Learning for Joint Object Search

We examine the problem of joint top-down active search of multiple objects under interaction, e.g., person riding a bicycle, cups held by the table, etc.. Such objects under interaction often can provide contextual cues to each other to facilitate more efficient search. By treating each detector as an agent, we present the first collaborative multi-agent deep reinforcement learning algorithm to learn the optimal policy for joint active object localization, which effectively exploits such beneficial contextual information. We learn inter-agent communication through cross connections with gates between the Q-networks, which is facilitated by a novel multi-agent deep Q-learning algorithm with joint exploitation sampling. We verify our proposed method on multiple object detection benchmarks. Not only does our model help to improve the performance of state-of-the-art active localization models, it also reveals interesting co-detection patterns that are intuitively interpretable

Systems approaches and algorithms for discovery of combinatorial therapies

Effective therapy of complex diseases requires control of highly non-linear complex networks that remain incompletely characterized. In particular, drug intervention can be seen as control of signaling in cellular networks. Identification of control parameters presents an extreme challenge due to the combinatorial explosion of control possibilities in combination therapy and to the incomplete knowledge of the systems biology of cells. In this review paper we describe the main current and proposed approaches to the design of combinatorial therapies, including the empirical methods used now by clinicians and alternative approaches suggested recently by several authors. New approaches for designing combinations arising from systems biology are described. We discuss in special detail the design of algorithms that identify optimal control parameters in cellular networks based on a quantitative characterization of control landscapes, maximizing utilization of incomplete knowledge of the state and structure of intracellular networks. The use of new technology for high-throughput measurements is key to these new approaches to combination therapy and essential for the characterization of control landscapes and implementation of the algorithms. Combinatorial optimization in medical therapy is also compared with the combinatorial optimization of engineering and materials science and similarities and differences are delineated.Comment: 25 page

Dagstuhl Reports : Volume 1, Issue 2, February 2011

Online Privacy: Towards Informational Self-Determination on the Internet (Dagstuhl Perspectives Workshop 11061) : Simone Fischer-Hübner, Chris Hoofnagle, Kai Rannenberg, Michael Waidner, Ioannis Krontiris and Michael Marhöfer Self-Repairing Programs (Dagstuhl Seminar 11062) : Mauro Pezzé, Martin C. Rinard, Westley Weimer and Andreas Zeller Theory and Applications of Graph Searching Problems (Dagstuhl Seminar 11071) : Fedor V. Fomin, Pierre Fraigniaud, Stephan Kreutzer and Dimitrios M. Thilikos Combinatorial and Algorithmic Aspects of Sequence Processing (Dagstuhl Seminar 11081) : Maxime Crochemore, Lila Kari, Mehryar Mohri and Dirk Nowotka Packing and Scheduling Algorithms for Information and Communication Services (Dagstuhl Seminar 11091) Klaus Jansen, Claire Mathieu, Hadas Shachnai and Neal E. Youn

Non-L\'evy mobility patterns of Mexican Me'Phaa peasants searching for fuelwood

We measured mobility patterns that describe walking trajectories of individual Me'Phaa peasants searching and collecting fuelwood in the forests of "La Monta\~na de Guerrero" in Mexico. These one-day excursions typically follow a mixed pattern of nearly-constant steps when individuals displace from their homes towards potential collecting sites and a mixed pattern of steps of different lengths when actually searching for fallen wood in the forest. Displacements in the searching phase seem not to be compatible with L\'evy flights described by power-laws with optimal scaling exponents. These findings however can be interpreted in the light of deterministic searching on heavily degraded landscapes where the interaction of the individuals with their scarce environment produces alternative searching strategies than the expected L\'evy flights. These results have important implications for future management and restoration of degraded forests and the improvement of the ecological services they may provide to their inhabitants.Comment: 15 pages, 4 figures. First version submitted to Human Ecology. The final publication will be available at http://www.springerlink.co

Vision of a Visipedia

The web is not perfect: while text is easily searched and organized, pictures (the vast majority of the bits that one can find online) are not. In order to see how one could improve the web and make pictures first-class citizens of the web, I explore the idea of Visipedia, a visual interface for Wikipedia that is able to answer visual queries and enables experts to contribute and organize visual knowledge. Five distinct groups of humans would interact through Visipedia: users, experts, editors, visual workers, and machine vision scientists. The latter would gradually build automata able to interpret images. I explore some of the technical challenges involved in making Visipedia happen. I argue that Visipedia will likely grow organically, combining state-of-the-art machine vision with human labor