The utility of the nitric oxide electrochemical sensor in biomedical research

In recent years World Precision Instruments Inc. (WPI) produced for commercial use a selective and sensitive electrochemical sensor for the detection of the important biological free radical nitric oxide (NO). Though many kinds of NO sensors are now commercially available WPI offers a range of sensors of variable size and applicability for the detection of NO in vivo and in in vitro biomedical samples. This article overviews the working characteristics of the sensors and their utility for biomedical research

Recent Progress in Optical Sensors for Biomedical Diagnostics

In recent years, several types of optical sensors have been probed for their aptitude in healthcare biosensing, making their applications in biomedical diagnostics a rapidly evolving subject. Optical sensors show versatility amongst different receptor types and even permit the integration of different detection mechanisms. Such conjugated sensing platforms facilitate the exploitation of their neoteric synergistic characteristics for sensor fabrication. This paper covers nearly 250 research articles since 2016 representing the emerging interest in rapid, reproducible and ultrasensitive assays in clinical analysis. Therefore, we present an elaborate review of biomedical diagnostics with the help of optical sensors working on varied principles such as surface plasmon resonance, localised surface plasmon resonance, evanescent wave fluorescence, bioluminescence and several others. These sensors are capable of investigating toxins, proteins, pathogens, disease biomarkers and whole cells in varied sensing media ranging from water to buffer to more complex environments such as serum, blood or urine. Hence, the recent trends discussed in this review hold enormous potential for the widespread use of optical sensors in early-stage disease prediction and point-of-care testing devices.DFG, 428780268, Biomimetische Rezeptoren auf NanoMIP-Basis zur Virenerkennung und -entfernung mittels integrierter Ansätz

Development of Wearable Systems for Ubiquitous Healthcare Service Provisioning

This paper reports on the development of a wearable system using wireless biomedical sensors for ubiquitous healthcare service provisioning. The prototype system is developed to address current healthcare challenges such as increasing cost of services, inability to access diverse services, low quality services and increasing population of elderly as experienced globally. The biomedical sensors proactively collect physiological data of remote patients to recommend diagnostic services. The prototype system is designed to monitor oxygen saturation level (SpO2), Heart Rate (HR), activity and location of the elderly. Physiological data collected are uploaded to a Health Server (HS) via GPRS/Internet for analysis.Comment: 6 pages, 3 figures, APCBEE Procedia 7, 2013. arXiv admin note: substantial text overlap with arXiv:1309.154

Sensors for biomedical applications

This paper considers the impact during the last decade of modern IC technology, microelectronics, thin- and thick-film technology, fibre optic technology, etc. on the development of sensors for biomedical applications

High-Resolution ADCs Design in Image Sensors

This paper presents design considerations for high-resolution and high-linearity ADCs for biomedical imaging ap-plications. The work discusses how to improve dynamic spec-ifications such as Spurious Free Dynamic Range (SFDR) and Signal-to-Noise-and-Distortion Ratio (SNDR) in ultra-low power and high-resolution analog-to-digital converters (ADCs) including successive approximation register (SAR) for biomedical imaging application. The results show that with broad range of mismatch error, the SFDR is enhanced by about 10 dB with the proposed performance enhancement technique, which makes it suitable for high resolution image sensors sensing systems

Advances in Optical Biomedical Sensing Technology

A study of the global healthcare trends shows that more people need health care across different ages and nations of the World. Therefore, there is a rapid growth and expansion of Healthcare Industry globally. This has led to increased demand on advanced biomedical sensors and devices for diagnosis, monitoring, treatment and care. This paper provides an overview of some recent developments in optical biomedical sensing technology. In this paper, the types, uses and unique benefits of novel optical sensors for biomedical applications are presented

Wireless actuation of micromechanical resonators

The wireless transfer of power is of fundamental and technical interest, with applications ranging from the remote operation of consumer electronics and implanted biomedical devices and sensors to the actuation of devices for which hard-wired power sources are neither desirable nor practical. In particular, biomedical devices that are implanted in the body or brain require small-footprint power receiving elements for wireless charging, which can be accomplished by micromechanical resonators. Moreover, for fundamental experiments, the ultralow-power wireless operation of micromechanical resonators in the microwave range can enable the performance of low-temperature studies of mechanical systems in the quantum regime, where the heat carried by the electrical wires in standard actuation techniques is detrimental to maintaining the resonator in a quantum state. Here we demonstrate the successful actuation of micron-sized silicon-based piezoelectric resonators with resonance frequencies ranging from 36 to 120 MHz at power levels of nanowatts and distances of ~3 feet, including comprehensive polarization, distance and power dependence measurements. Our unprecedented demonstration of the wireless actuation of micromechanical resonators via electric-field coupling down to nanowatt levels may enable a multitude of applications that require the wireless control of sensors and actuators based on micromechanical resonators, which was inaccessible until now.http://nano.bu.edu/Papers_files/micronano201636.pdfPublished versio

Wireless Medical Sensor Networks: Design Requirements and Enabling Technologies

This article analyzes wireless communication protocols that could be used in healthcare environments (e.g., hospitals and small clinics) to transfer real-time medical information obtained from noninvasive sensors. For this purpose the features of the three currently most widely used protocols—namely, Bluetooth® (IEEE 802.15.1), ZigBee (IEEE 802.15.4), and Wi-Fi (IEEE 802.11)—are evaluated and compared. The important features under consideration include data bandwidth, frequency band, maximum transmission distance, encryption and authentication methods, power consumption, and current applications. In addition, an overview of network requirements with respect to medical sensor features, patient safety and patient data privacy, quality of service, and interoperability between other sensors is briefly presented. Sensor power consumption is also discussed because it is considered one of the main obstacles for wider adoption of wireless networks in medical applications. The outcome of this assessment will be a useful tool in the hands of biomedical engineering researchers. It will provide parameters to select the most effective combination of protocols to implement a specific wireless network of noninvasive medical sensors to monitor patients remotely in the hospital or at home