43,907 research outputs found
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
Universal in vivo Textural Model for Human Skin based on Optical Coherence Tomograms
Currently, diagnosis of skin diseases is based primarily on visual pattern
recognition skills and expertise of the physician observing the lesion. Even
though dermatologists are trained to recognize patterns of morphology, it is
still a subjective visual assessment. Tools for automated pattern recognition
can provide objective information to support clinical decision-making.
Noninvasive skin imaging techniques provide complementary information to the
clinician. In recent years, optical coherence tomography has become a powerful
skin imaging technique. According to specific functional needs, skin
architecture varies across different parts of the body, as do the textural
characteristics in OCT images. There is, therefore, a critical need to
systematically analyze OCT images from different body sites, to identify their
significant qualitative and quantitative differences. Sixty-three optical and
textural features extracted from OCT images of healthy and diseased skin are
analyzed and in conjunction with decision-theoretic approaches used to create
computational models of the diseases. We demonstrate that these models provide
objective information to the clinician to assist in the diagnosis of
abnormalities of cutaneous microstructure, and hence, aid in the determination
of treatment. Specifically, we demonstrate the performance of this methodology
on differentiating basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)
from healthy tissue
Cancer diagnosis using deep learning: A bibliographic review
In this paper, we first describe the basics of the field of cancer diagnosis, which includes steps of cancer diagnosis followed by the typical classification methods used by doctors, providing a historical idea of cancer classification techniques to the readers. These methods include Asymmetry, Border, Color and Diameter (ABCD) method, seven-point detection method, Menzies method, and pattern analysis. They are used regularly by doctors for cancer diagnosis, although they are not considered very efficient for obtaining better performance. Moreover, considering all types of audience, the basic evaluation criteria are also discussed. The criteria include the receiver operating characteristic curve (ROC curve), Area under the ROC curve (AUC), F1 score, accuracy, specificity, sensitivity, precision, dice-coefficient, average accuracy, and Jaccard index. Previously used methods are considered inefficient, asking for better and smarter methods for cancer diagnosis. Artificial intelligence and cancer diagnosis are gaining attention as a way to define better diagnostic tools. In particular, deep neural networks can be successfully used for intelligent image analysis. The basic framework of how this machine learning works on medical imaging is provided in this study, i.e., pre-processing, image segmentation and post-processing. The second part of this manuscript describes the different deep learning techniques, such as convolutional neural networks (CNNs), generative adversarial models (GANs), deep autoencoders (DANs), restricted Boltzmann’s machine (RBM), stacked autoencoders (SAE), convolutional autoencoders (CAE), recurrent neural networks (RNNs), long short-term memory (LTSM), multi-scale convolutional neural network (M-CNN), multi-instance learning convolutional neural network (MIL-CNN). For each technique, we provide Python codes, to allow interested readers to experiment with the cited algorithms on their own diagnostic problems. The third part of this manuscript compiles the successfully applied deep learning models for different types of cancers. Considering the length of the manuscript, we restrict ourselves to the discussion of breast cancer, lung cancer, brain cancer, and skin cancer. The purpose of this bibliographic review is to provide researchers opting to work in implementing deep learning and artificial neural networks for cancer diagnosis a knowledge from scratch of the state-of-the-art achievements
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