26 research outputs found
Employability & Competences
The book is the final report of the researches, discussions, conversations around and about the Project PRIN Employability & Competences which took place on March 9th-Ââ11th, 2017 within an International Conference at the University of Florence. It was the final event of the project PRIN2012LATR9N which aims were: «to design innovative programs for higher education, to promote personalized and learner-centered teaching and learning, to build on job competencies, to value talents to create new work opportunities, to support young adults during their employment emergency, as a response to socio economic crisis and as a citizenship action». The research activities concerned the main phases of the studentsâ academic life: career guidance upon entry, personalized teaching, career calling, professional vocation, profession building activities such as internships and work related experiences, and lastly job placement
Routledge Handbook of Chinese Medicine
The Routledge Handbook of Chinese Medicine is an extensive, interdisciplinary guide to the nature of traditional medicine and healing in the Chinese cultural region, and its plural epistemologies. Established experts and the next generation of scholars interpret the ways in which Chinese medicine has been understood and portrayed from the beginning of the empire (third century BCE) to the globalisation of Chinese products and practices in the present day, taking in subjects from ancient medical writings to therapeutic movement, to talismans for healing and traditional medicines that have inspired global solutions to contemporary epidemics. The volume is divided into seven parts:
Longue Durée and Formation of Institutions and Traditions
Sickness and Healing
Food and Sex
Spiritual and Orthodox Religious Practices
The World of Sinographic Medicine
Wider Diasporas
Negotiating Modernity
This handbook therefore introduces the broad range of ideas and techniques that comprise pre-modern medicine in China, and the historiographical and ethnographic approaches that have illuminated them. It will prove a useful resource to students and scholars of Chinese studies, and the history of medicine and anthropology. It will also be of interest to practitioners, patients and specialists wishing to refresh their knowledge with the latest developments in the field.
The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 licens
Men's Experiences on Active Surveillance: From Diagnosis to Discontinuation
Over 1.4 million men were diagnosed with prostate cancer worldwide in 2020. Due to increased early testing and detection, higher numbers are being diagnosed with low risk, localised prostate cancer. Active surveillance is the recommended treatment option for patients with low risk, localised prostate cancer, as it provides patients the opportunity to delay definitive treatments until clinically necessary whilst actively monitoring progression. However, there is no global consensus on eligibility criteria, best practice for management, or triggers for discontinuation, and therefore uptake, practice, and patient experiences may vary greatly across clinics and countries. In order to (a) understand patient experiences during active surveillance, (b) inform changes to active surveillance management that align with the needs of patients, and (c) identify critical research areas, consideration of the individual, social and ecological factors that influence patient experiences is required. To reach this aim, this thesis includes four studies using a range of methodologies to investigate patient experiences from diagnosis to active surveillance discontinuation. A fifth study focusing on enhancing methodology in this research domain is also included. Study One used qualitative methods to explore patient and partner experiences after low risk localised prostate cancer diagnosis as they navigated the treatment decision between active surveillance and definitive treatment. Study Two systematically reviewed the literature on patientsâ unmet supportive care needs during active surveillance. Data for studies Three and Four were collected together using a mix of methodologies (quantitative survey and qualitative interviews). Given the outcomes of the systematic review (Study Two), in Study Three we investigated the unmet supportive care needs and psychological wellbeing of patients during active surveillance. In Study Four, we explored the personal and/or medical reasons patients discontinue active surveillance and move to definitive treatment. Finally, Study Five was a randomised trial embedded within Studies Three and Four to examine the influence of different unconditional monetary incentives on survey response rates. This body of research demonstrated that whilst patients on active surveillance generally report positive experiences and outcomes, a significant proportion report unmet supportive care needs across informational, sexual, physical, psychological, and patient care domains. Patients on active surveillance frequently report experiencing fear of cancer progression, appear to be greatly influenced by a variety of factors when navigating treatment decision (both at diagnosis and prior to discontinuation), and report uncertainty about active surveillance and their future. In addition, we observed that prostate cancer patients are no more likely to respond to long surveys when provided a larger unconditional monetary incentive (10AUD). Further research to inform the development of supportive care interventions which directly address patient needs, align with their preferences, and consider their perspectives, is essential for improving active surveillance uptake, adherence, and overall experience for both patients and their partners/close allies. Doing so will require a strong engagement in research, which may be improved by using a variety of engagement strategies such as unconditional incentives, though further research is required.Thesis (Ph.D.) -- University of Adelaide, School of Medicine, 202
A global collaboration to study intimate partner violence-related head trauma: The ENIGMA consortium IPV working group
Intimate partner violence includes psychological aggression, physical violence, sexual violence, and stalking from a current or former intimate partner. Past research suggests that exposure to intimate partner violence can impact cognitive and psychological functioning, as well as neurological outcomes. These seem to be compounded in those who suffer a brain injury as a result of trauma to the head, neck or body due to physical and/or sexual violence. However, our understanding of the neurobehavioral and neurobiological effects of head trauma in this population is limited due to factors including difficulty in accessing/recruiting participants, heterogeneity of samples, and premorbid and comorbid factors that impact outcomes. Thus, the goal of the Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium Intimate Partner Violence Working Group is to develop a global collaboration that includes researchers, clinicians, and other key community stakeholders. Participation in the working group can include collecting harmonized data, providing data for meta- and mega-analysis across sites, or stakeholder insight on key clinical research questions, promoting safety, participant recruitment and referral to support services. Further, to facilitate the mega-analysis of data across sites within the working group, we provide suggestions for behavioral surveys, cognitive tests, neuroimaging parameters, and genetics that could be used by investigators in the early stages of study design. We anticipate that the harmonization of measures across sites within the working group prior to data collection could increase the statistical power in characterizing how intimate partner violence-related head trauma impacts long-term physical, cognitive, and psychological health
Leading from the North
Leading from the North aims to improve public dialogue around the future of Northern Australia to underpin robust and flexible planning and policy frameworks. A number of areas are addressed including social infrastructure, governance systems, economic, business and regional development, climate and its implications, the roles and trends in demography and migration in the region. This book not only speaks to the issues of development in Northern Australia but also other regional areas, and examines opportunities for growth with changing economies and technologies. The authors of this book consist of leading researchers, academics and experts from Charles Darwin University, The Australian National University, James Cook University, the Australian Institute of Marine Science and many other collaborative partners. Many of the authors have first-hand experience of living and working in Northern Australia. They understand the real issues and challenges faced by people living in Northern Australia and other similar regional areas. Backed by their expertise and experience, the authors present their discussions and findings from a local perspective
Frameshift mutations at the C-terminus of HIST1H1E result in a specific DNA hypomethylation signature
BACKGROUND: We previously associated HIST1H1E mutations causing Rahman syndrome with a specific genome-wide methylation pattern. RESULTS: Methylome analysis from peripheral blood samples of six affected subjects led us to identify a specific hypomethylated profile. This "episignature" was enriched for genes involved in neuronal system development and function. A computational classifier yielded full sensitivity and specificity in detecting subjects with Rahman syndrome. Applying this model to a cohort of undiagnosed probands allowed us to reach diagnosis in one subject. CONCLUSIONS: We demonstrate an epigenetic signature in subjects with Rahman syndrome that can be used to reach molecular diagnosis
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Medicines Management after Hospital Discharge: Patientsâ Personal and Professional Networks
Improving the safety of medicines management when people leave hospital is an international priority. There is evidence that poor co-ordination of medicines between providers can cause preventable harm to patients, yet there is insufficient evidence of the structure and function of the medicines management system that patients experience. This research used a mixed-methods social network analysis to determine the structure, content and function of that system as experienced by patients. Patientsâ networks comprised a range of loosely connected healthcare professionals in different organisations and informal, personal contacts. Networks performed multiple functions, including health condition management, and orienting patients concerning their medicines. Some patients experienced safety incidents as a function of their networks. Staff discharging patients from hospital were also observed. Contributory factors that were found to risk the safety of patientsâ discharge with medicines included active failures, individual factors and local working conditions. System defences involving staff and patients were also observed. The study identified how patients often co-ordinated a system that lacked personalisation and there is a need to provide more consistent support for patientsâ self-management of medicines after they leave hospital. This could be achieved through interventions that include patientsâ informal contacts in supporting their medicines use, enhancing their resilience to preventable harm, and developing and testing the role of a âmedicines key workerâ in safely managing the transfer of care. The role of GP practices in co-ordinating the involvement of multiple professionals in patient polypharmacy needs to be further explored.University of Bradford studentshi