3,004,247 research outputs found
Investigation of Application Efficiency of Two Rows Blades in the Fan Vent Installation
Представлено результати експериментального дослідження застосування дворядних лопаткових вінців для підвищення напору вентиляторів вентиляційних установок ежекторного тип
Fatores determinantes da eficiência do setor bancário em Portugal: uma aplicação através de modelos de regressão fracional
The participation in the Euro area and the current financial crisis substantially conditioned the development of the Portuguese banking industry, for which is expected a continuous fall in income and a growing competitive pressure, improving the need to look carefully to issues as efficiency as an essential survival factor. Efficiency indicators of the main banks operating in Portugal were measured through DEA methodology. The application of two-stage models allowed circumventing the usual problems inherent to the coexistence of the production and intermediation approaches. The application of regression for proportions, more appropriate than traditional linear and Tobit regressions, to deal with the fractional nature of the DEA scores, allowed the identification of efficiency determinant factors for the main banks operating in Portugal. The fractional regression models demonstrate evidence of improved specification comparing to traditional regression models. The variables that appear to major influence on overall efficiency are internationalization, size and type of ownership of capital.info:eu-repo/semantics/publishedVersio
Iso-energy-efficiency: An approach to power-constrained parallel computation
Future large scale high performance supercomputer systems require high energy efficiency to achieve exaflops computational power and beyond. Despite the need to understand energy efficiency in high-performance systems, there are few techniques to evaluate energy efficiency at scale. In this paper, we propose a system-level iso-energy-efficiency model to analyze, evaluate and predict energy-performance of data intensive parallel applications with various execution patterns running on large scale power-aware clusters. Our analytical model can help users explore the effects of machine and application dependent characteristics on system energy efficiency and isolate efficient ways to scale system parameters (e.g. processor count, CPU power/frequency, workload size and network bandwidth) to balance energy use and performance. We derive our iso-energy-efficiency model and apply it to the NAS Parallel Benchmarks on two power-aware clusters. Our results indicate that the model accurately predicts total system energy consumption within 5% error on average for parallel applications with various execution and communication patterns. We demonstrate effective use of the model for various application contexts and in scalability decision-making
Application of the EXtrapolated Efficiency Method (EXEM) to infer the gamma-cascade detection efficiency in the actinide region
The study of transfer-induced gamma-decay probabilities is very useful for
understanding the surrogate-reaction method and, more generally, for
constraining statistical-model calculations. One of the main difficulties in
the measurement of gamma-decay probabilities is the determination of the
gamma-cascade detection efficiency. In [Nucl. Instrum. Meth. A 700, 59 (2013)]
we developed the Extrapolated Efficiency Method (EXEM), a new method to measure
this quantity. In this work, we have applied, for the first time, the EXEM to
infer the gamma-cascade detection efficiency in the actinide region. In
particular, we have considered the 238U(d,p)239U and 238U(3He,d)239Np
reactions. We have performed Hauser-Feshbach calculations to interpret our
results and to verify the hypothesis on which the EXEM is based. The
determination of fission and gamma-decay probabilities of 239Np below the
neutron separation energy allowed us to validate the EXEM
Dynamic Efficiency Estimation: An Application to US Electric Utilities
The static production efficiency model and the dynamic duality model of intertemporal decision making using a parametric approach have been continuously developed but in separate direction. In this study the static shadow cost approach and the dynamic duality model of intertemporal decision making are integrated to formulate theoretical and econometric models of dynamic efficiency with intertemporal cost minimizing firm behavior. The dynamic efficiency model is empirically implemented using a panel data set of 72 U.S. major investor-owned electric utilities using fossil-fuel fired steam electric power generation during the time period of 1986 to 1999. The major results of this study are that most electric utilities in this study underutilized fuel relative to the aggregated labor and maintenance input and they overutilized capital in production. Electric utilities with relatively high technical inefficiency of variable inputs demand in production in states adopting a deregulation plan improve the performance of the utilities. The estimates of the input price elasticities present the substitution possibilities among the inputs. Finally, the results suggest evidence of increasing returns to scale in the production of the electricity industry.
Application of multimedia technologies for improving the efficiency of foreign students teaching
Enhanced analysis of real-time PCR data by using a variable efficiency model : FPK-PCR
Current methodology in real-time Polymerase chain reaction (PCR) analysis performs well provided PCR efficiency remains constant over reactions. Yet, small changes in efficiency can lead to large quantification errors. Particularly in biological samples, the possible presence of inhibitors forms a challenge. We present a new approach to single reaction efficiency calculation, called Full Process Kinetics-PCR (FPK-PCR). It combines a kinetically more realistic model with flexible adaptation to the full range of data. By reconstructing the entire chain of cycle efficiencies, rather than restricting the focus on a 'window of application', one extracts additional information and loses a level of arbitrariness. The maximal efficiency estimates returned by the model are comparable in accuracy and precision to both the golden standard of serial dilution and other single reaction efficiency methods. The cycle-to-cycle changes in efficiency, as described by the FPK-PCR procedure, stay considerably closer to the data than those from other S-shaped models. The assessment of individual cycle efficiencies returns more information than other single efficiency methods. It allows in-depth interpretation of real-time PCR data and reconstruction of the fluorescence data, providing quality control. Finally, by implementing a global efficiency model, reproducibility is improved as the selection of a window of application is avoided
Network-aware design-space exploration of a power-efficient embedded application
The paper presents the design and multi-parameter optimization of a networked embedded application for the health-care domain. Several hardware, software, and application parameters, such as clock frequency, sensor sampling rate, data packet rate, are tuned at design- and run-time according to application specifications and operating conditions to optimize hardware requirements, packet loss, power consumption. Experimental results show that further power efficiency can be achieved by considering also communication aspects during design space exploratio
pH-Sensitive Chitosan–Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells
Chitosan has been extensively studied as a genetic drug delivery platform. However, its efficiency is limited by the strength of DNA and RNA binding. Expecting a reduced binding strength of cargo with chitosan, we proposed including heparin as a competing polyanion in the polyplexes. We developed chitosan–heparin nanoparticles by a one-step process for the local delivery of oligonucleotides. The size of the polyplexes was dependent on the mass ratio of polycation to polyanion. The mechanism of oligonucleotide release was pH-dependent and associated with polyplex swelling and collapse of the polysaccharide network. Inclusion of heparin enhanced the oligonucleotide release from the chitosan-based polyplexes. Furthermore, heparin reduced the toxicity of polyplexes in the cultured cells. The cell uptake of chitosan–heparin polyplexes was equal to that of chitosan polyplexes, but heparin increased the transfection efficiency of the polyplexes two-fold. The application of chitosan–heparin small interfering RNA (siRNA) targeted to vascular endothelial growth factor (VEGF) silencing of ARPE-19 cells was 25% higher. Overall, chitosan–heparin polyplexes showed a significant improvement of gene release inside the cells, transfection, and gene silencing efficiency in vitro, suggesting that this fundamental strategy can further improve the transfection efficiency with application of non-viral vectors
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