2,765 research outputs found
On the Use of XML in Medical Imaging Web-Based Applications
The rapid growth of digital technology in medical fields over recent years has increased the need for applications able to manage patient medical records, imaging data, and chart information. Web-based applications are implemented with the purpose to link digital databases, storage and transmission protocols, management of large volumes of data and security concepts, allowing the possibility to read, analyze, and even diagnose remotely from the medical center where the information was acquired. The objective of this paper is to analyze the use of the Extensible Markup Language (XML) language in web-based applications that aid in diagnosis or treatment of patients, considering how this protocol allows indexing and exchanging the huge amount of information associated with each medical case. The purpose of this paper is to point out the main advantages and drawbacks of the XML technology in order to provide key ideas for future web-based applicationsPeer ReviewedPostprint (author's final draft
Towards a New Science of a Clinical Data Intelligence
In this paper we define Clinical Data Intelligence as the analysis of data
generated in the clinical routine with the goal of improving patient care. We
define a science of a Clinical Data Intelligence as a data analysis that
permits the derivation of scientific, i.e., generalizable and reliable results.
We argue that a science of a Clinical Data Intelligence is sensible in the
context of a Big Data analysis, i.e., with data from many patients and with
complete patient information. We discuss that Clinical Data Intelligence
requires the joint efforts of knowledge engineering, information extraction
(from textual and other unstructured data), and statistics and statistical
machine learning. We describe some of our main results as conjectures and
relate them to a recently funded research project involving two major German
university hospitals.Comment: NIPS 2013 Workshop: Machine Learning for Clinical Data Analysis and
Healthcare, 201
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Privacy-preserving model learning on a blockchain network-of-networks.
ObjectiveTo facilitate clinical/genomic/biomedical research, constructing generalizable predictive models using cross-institutional methods while protecting privacy is imperative. However, state-of-the-art methods assume a "flattened" topology, while real-world research networks may consist of "network-of-networks" which can imply practical issues including training on small data for rare diseases/conditions, prioritizing locally trained models, and maintaining models for each level of the hierarchy. In this study, we focus on developing a hierarchical approach to inherit the benefits of the privacy-preserving methods, retain the advantages of adopting blockchain, and address practical concerns on a research network-of-networks.Materials and methodsWe propose a framework to combine level-wise model learning, blockchain-based model dissemination, and a novel hierarchical consensus algorithm for model ensemble. We developed an example implementation HierarchicalChain (hierarchical privacy-preserving modeling on blockchain), evaluated it on 3 healthcare/genomic datasets, as well as compared its predictive correctness, learning iteration, and execution time with a state-of-the-art method designed for flattened network topology.ResultsHierarchicalChain improves the predictive correctness for small training datasets and provides comparable correctness results with the competing method with higher learning iteration and similar per-iteration execution time, inherits the benefits of the privacy-preserving learning and advantages of blockchain technology, and immutable records models for each level.DiscussionHierarchicalChain is independent of the core privacy-preserving learning method, as well as of the underlying blockchain platform. Further studies are warranted for various types of network topology, complex data, and privacy concerns.ConclusionWe demonstrated the potential of utilizing the information from the hierarchical network-of-networks topology to improve prediction
The Brave New World of Genetic Biobanks: International Lessons for a Potential United States Biobank
360 Quantified Self
Wearable devices with a wide range of sensors have contributed to the rise of
the Quantified Self movement, where individuals log everything ranging from the
number of steps they have taken, to their heart rate, to their sleeping
patterns. Sensors do not, however, typically sense the social and ambient
environment of the users, such as general life style attributes or information
about their social network. This means that the users themselves, and the
medical practitioners, privy to the wearable sensor data, only have a narrow
view of the individual, limited mainly to certain aspects of their physical
condition.
In this paper we describe a number of use cases for how social media can be
used to complement the check-up data and those from sensors to gain a more
holistic view on individuals' health, a perspective we call the 360 Quantified
Self. Health-related information can be obtained from sources as diverse as
food photo sharing, location check-ins, or profile pictures. Additionally,
information from a person's ego network can shed light on the social dimension
of wellbeing which is widely acknowledged to be of utmost importance, even
though they are currently rarely used for medical diagnosis. We articulate a
long-term vision describing the desirable list of technical advances and
variety of data to achieve an integrated system encompassing Electronic Health
Records (EHR), data from wearable devices, alongside information derived from
social media data.Comment: QCRI Technical Repor
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