Health Technology Assessment for In Silico Medicine: Social, Ethical and Legal Aspects

The application of in silico medicine is constantly growing in the prevention, diagnosis, and treatment of diseases. These technologies allow us to support medical decisions and self- management and reduce, refine, and partially replace real studies of medical technologies. In silico medicine may challenge some key principles: transparency and fairness of data usage; data privacy and protection across platforms and systems; data availability and quality; data integration and interoperability; intellectual property; data sharing; equal accessibility for persons and populations. Several social, ethical, and legal issues may consequently arise from its adoption. In this work, we provide an overview of these issues along with some practical suggestions for their assessment from a health technology assessment perspective. We performed a narrative review with a search on MEDLINE/Pubmed, ISI Web of Knowledge, Scopus, and Google Scholar. The following key aspects emerge as general reflections with an impact on the operational level: cultural resistance, level of expertise of users, degree of patient involvement, infrastructural requirements, risks for health, respect of several patients’ rights, potential discriminations for access and use of the technology, and intellectual property of innovations. Our analysis shows that several challenges still need to be debated to allow in silico medicine to express all its potential in healthcare processes

Human Resources for Health Migration: global policy responses, initiatives, and emerging issues

This report identifies and maps contemporary global policy responses to, and initiatives on, international HRH migration, with particular reference to low‐income source countries. It reports on a systematic review and analysis of the responses and initiatives of twelve multilateral organisations and global fora: European Union; Global Forum on Migration and Development; Global Health Workforce Alliance; International Labour Organization; International Organization for Migration; Organisation for Economic Cooperation and Development; Pan‐American Health Organization; UN Global Migration Group; UN High‐Level Dialogue on Migration and Development; World Bank; World Health Organization; and the World Trade Organization. The report documents how these global policy actors are presently engaging with the HRH migration field through their activities, initiatives and policy responses. It situates this engagement within global policy initiatives spanning health, migration and development. In addition to reviewing and mapping current initiatives and policy responses and their outcomes, the report identifies emerging issues, upcoming promising initiatives and global policy scenarios

Science and Technology Governance and Ethics - A Global Perspective from Europe, India and China

This book analyzes the possibilities for effective global governance of science in Europe, India and China. Authors from the three regions join forces to explore how ethical concerns over new technologies can be incorporated into global science and technology policies. The first chapter introduces the topic, offering a global perspective on embedding ethics in science and technology policy. Chapter Two compares the institutionalization of ethical debates in science, technology and innovation policy in three important regions: Europe, India and China. The third chapter explores public perceptions of science and technology in these same three regions. Chapter Four discusses public engagement in the governance of science and technology, and Chapter Five reviews science and technology governance and European values. The sixth chapter describes and analyzes values demonstrated in the constitution of the People’s Republic of China. Chapter Seven describes emerging evidence from India on the uses of science and technology for socio-economic development, and the quest for inclusive growth. In Chapter Eight, the authors propose a comparative framework for studying global ethics in science and technology. The following three chapters offer case studies and analysis of three emerging industries in India, China and Europe: new food technologies, nanotechnology and synthetic biology. Chapter 12 gathers all these threads for a comprehensive discussion on incorporating ethics into science and technology policy. The analysis is undertaken against the backdrop of different value systems and varying levels of public perception of risks and benefits. The book introduces a common analytical framework for the comparative discussion of ethics at the international level. The authors offer policy recommendations for effective collaboration among the three regions, to promote responsible governance in science and technology and a common analytical perspective in ethics

Data analytics and algorithms in policing in England and Wales: Towards a new policy framework

RUSI was commissioned by the Centre for Data Ethics and Innovation (CDEI) to conduct an independent study into the use of data analytics by police forces in England and Wales, with a focus on algorithmic bias. The primary purpose of the project is to inform CDEI’s review of bias in algorithmic decision-making, which is focusing on four sectors, including policing, and working towards a draft framework for the ethical development and deployment of data analytics tools for policing. This paper focuses on advanced algorithms used by the police to derive insights, inform operational decision-making or make predictions. Biometric technology, including live facial recognition, DNA analysis and fingerprint matching, are outside the direct scope of this study, as are covert surveillance capabilities and digital forensics technology, such as mobile phone data extraction and computer forensics. However, because many of the policy issues discussed in this paper stem from general underlying data protection and human rights frameworks, these issues will also be relevant to other police technologies, and their use must be considered in parallel to the tools examined in this paper. The project involved engaging closely with senior police officers, government officials, academics, legal experts, regulatory and oversight bodies and civil society organisations. Sixty nine participants took part in the research in the form of semi-structured interviews, focus groups and roundtable discussions. The project has revealed widespread concern across the UK law enforcement community regarding the lack of official national guidance for the use of algorithms in policing, with respondents suggesting that this gap should be addressed as a matter of urgency. Any future policy framework should be principles-based and complement existing police guidance in a ‘tech-agnostic’ way. Rather than establishing prescriptive rules and standards for different data technologies, the framework should establish standardised processes to ensure that data analytics projects follow recommended routes for the empirical evaluation of algorithms within their operational context and evaluate the project against legal requirements and ethical standards. The new guidance should focus on ensuring multi-disciplinary legal, ethical and operational input from the outset of a police technology project; a standard process for model development, testing and evaluation; a clear focus on the human–machine interaction and the ultimate interventions a data driven process may inform; and ongoing tracking and mitigation of discrimination risk

A European research roadmap for optimizing societal impact of big data on environment and energy efficiency

We present a roadmap to guide European research efforts towards a socially responsible big data economy that maximizes the positive impact of big data in environment and energy efficiency. The goal of the roadmap is to allow stakeholders and the big data community to identify and meet big data challenges, and to proceed with a shared understanding of the societal impact, positive and negative externalities, and concrete problems worth investigating. It builds upon a case study focused on the impact of big data practices in the context of Earth Observation that reveals both positive and negative effects in the areas of economy, society and ethics, legal frameworks and political issues. The roadmap identifies European technical and non-technical priorities in research and innovation to be addressed in the upcoming five years in order to deliver societal impact, develop skills and contribute to standardization.Comment: 6 pages, 2 figures, 1 tabl

Privacy, Restriction, and Access: Legal and Ethical Dilemmas

This paper examines the intersection of privacy and access in archival repositories. Archival repositories are well known for containing restricted material, and for protecting the privacy of the donors. This literature review examines the need for restricted material from both legal and ethical standpoints, as well as discussing culturally sensitive materials while determining what archives and libraries can do to protect both themselves and their donors while enhancing accessibility and freedom of information