1,159 research outputs found

    The "Artificial Mathematician" Objection: Exploring the (Im)possibility of Automating Mathematical Understanding

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    Reuben Hersh confided to us that, about forty years ago, the late Paul Cohen predicted to him that at some unspecified point in the future, mathematicians would be replaced by computers. Rather than focus on computers replacing mathematicians, however, our aim is to consider the (im)possibility of human mathematicians being joined by “artificial mathematicians” in the proving practice—not just as a method of inquiry but as a fellow inquirer

    The New Crafts: On the Technization of the Workforce and the Occupationalization of Firms

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    [Excerpt] In the late 1960s and early 1970s American students were told that the value of a college education was declining (see Freeman 1976). Although liberal arts students were particularly discouraged by reports of recent graduates driving taxicabs, even the demand for engineers and other technical specialists seemed bleak. Two decades later, the headlines have reversed. Study after study proclaims that American children are performing more poorly on achievement tests than the children of most other industrialized nations. Employers complain of a shortage of skilled workers: young people are said to be ill-prepared for the demands of the workplace and older workers are said to lack the educational background requisite for retraining (Johnson and Packer 1987). Studies by labor economists have largely confirmed the employers\u27 contentions and foretell of even greater shortages of skilled labor in the near future (Bishop and Carter 1991)

    An Introduction to Systems Biology for Mathematical Programmers

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    Many recent advances in biology, medicine and health care are due to computational efforts that rely on new mathematical results. These mathematical tools lie in discrete mathematics, statistics & probability, and optimization, and when combined with savvy computational tools and an understanding of cellular biology they are capable of remarkable results. One of the most significant areas of growth is in the field of systems biology, where we are using detailed biological information to construct models that describe larger entities. This chapter is designed to be an introduction to systems biology for individuals in Operations Research (OR) and mathematical programming who already know the supporting mathematics but are unaware of current research in this field

    Worker Shortage, Outsourcing, and Immigration as Features of Computer Technology Competition between the United States and India

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    In this study, we examine questions relating to the state of competition between the United States and India in the field of computer technology. We consider whether there is continual increase in the outsourcing by American firms of computer service work abroad, claims of computer worker shortage, and claims of the need for increased immigration of foreign computer workers to deal with a supposed deterioration in American technology. We conclude, first, that both U.S. and Indian computer service companies and their potential clients prefer close collaboration rather than “arms length” relationships. As a result, service companies in both nations have made large efforts to set up business in each other’s country. Second, we find that the actual level of effort to hire workers in computer technology does not correspond to the intensity of need claimed by computer industry leaders. Finally, we conclude that the United States occupies a position of vigorous leadership in science and technology, evidenced by the largest number of graduates in those fields of any country, a number enhanced by a strong inflow of highly qualified students from other countries seeking advanced training and future careers her

    Modeling Biochemical Processes as Designed Systems

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    Being in the post-genomic era, there is a need for new methodologies from an interdisciplinary perspective, which can complement current genomics research. Bioinformatics and systems biology are rapidly growing research areas that are meeting this need. Operating with the assumption that there is design with a purpose, creationists provide a unique perspective for discovering order in the complexity of genes, regulatory networks, and biochemical reactions. Since the genome acts as an information storage system, it seems reasonable to apply design concepts, originating from computer and network programming, to make sense of genomic information. One such concept is that of design patterns, which has been formalized by programmers and analysts working with object-oriented programming (OOP). Several patterns are introduced and related to biochemical systems in the cell. A more detailed analysis of the observer pattern is made in the context of galactose metabolism in Saccharomyces cerevisiae. Since design patterns embody good OOP practice and do not specify a specific implementation, it is possible to explore a variety of implementations that can achieve regulation of galactose metabolism. This methodology can complement current research approaches by clarifying what is meant by system homology at the biochemical level

    Modeling Biochemical Processes as Designed Systems

    Get PDF
    Being in the post-genomic era, there is a need for new methodologies from an interdisciplinary perspective, which can complement current genomics research. Bioinformatics and systems biology are rapidly growing research areas that are meeting this need. Operating with the assumption that there is design with a purpose, creationists provide a unique perspective for discovering order in the complexity of genes, regulatory networks, and biochemical reactions. Since the genome acts as an information storage system, it seems reasonable to apply design concepts, originating from computer and network programming, to make sense of genomic information. One such concept is that of design patterns, which has been formalized by programmers and analysts working with object-oriented programming (OOP). Several patterns are introduced and related to biochemical systems in the cell. A more detailed analysis of the observer pattern is made in the context of galactose metabolism in Saccharomyces cerevisiae. Since design patterns embody good OOP practice and do not specify a specific implementation, it is possible to explore a variety of implementations that can achieve regulation of galactose metabolism. This methodology can complement current research approaches by clarifying what is meant by system homology at the biochemical level
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