Echocardiography

The book "Echocardiography - New Techniques" brings worldwide contributions from highly acclaimed clinical and imaging science investigators, and representatives from academic medical centers. Each chapter is designed and written to be accessible to those with a basic knowledge of echocardiography. Additionally, the chapters are meant to be stimulating and educational to the experts and investigators in the field of echocardiography. This book is aimed primarily at cardiology fellows on their basic echocardiography rotation, fellows in general internal medicine, radiology and emergency medicine, and experts in the arena of echocardiography. Over the last few decades, the rate of technological advancements has developed dramatically, resulting in new techniques and improved echocardiographic imaging. The authors of this book focused on presenting the most advanced techniques useful in today's research and in daily clinical practice. These advanced techniques are utilized in the detection of different cardiac pathologies in patients, in contributing to their clinical decision, as well as follow-up and outcome predictions. In addition to the advanced techniques covered, this book expounds upon several special pathologies with respect to the functions of echocardiography

Deep Learning Methods for Estimation of Elasticity and Backscatter Quantitative Ultrasound

Ultrasound (US) imaging is increasingly attracting the attention of both academic and industrial researchers due to being a real-time and nonionizing imaging modality. It is also less expensive and more portable compared to other medical imaging techniques. However, the granular appearance hinders the interpretation of US images, hindering its wider adoption. This granular appearance (also referred to as speckles) arises from the backscattered echo from microstructural components smaller than the ultrasound wavelength, which are called scatterers. While significant effort has been undertaken to reduce the appearance of speckles, they contain scatterer properties that are highly correlated with the microstructure of the tissue that can be employed to diagnose different types of disease. There are many properties that can be extracted from speckles that are clinically valuable, such as the elasticity and organization of scatterers. Analyzing the motion of scatterers in the presence of an internal or external force can be used to obtain the elastic properties of the tissue. The technique is called elastography and has been widely used to characterize the tissue. Estimating the scatterer organization (scatterer number density and coherent to diffuse scattering power) is also crucial as it provides information about tissue microstructure and potentially aids in disease diagnosis and treatment monitoring. This thesis proposes several deep learning-based methods to facilitate and improve the estimation of speckle motion and scatterer properties, potentially simplifying the interpretation of US images. In particular, we propose new methods for displacement estimation in Chapters 2 to 6 and introduce novel techniques in Chapters 7 to 11 to quantify scatterers’ number density and organization