Chi-square-based scoring function for categorization of MEDLINE citations

Objectives: Text categorization has been used in biomedical informatics for identifying documents containing relevant topics of interest. We developed a simple method that uses a chi-square-based scoring function to determine the likelihood of MEDLINE citations containing genetic relevant topic. Methods: Our procedure requires construction of a genetic and a nongenetic domain document corpus. We used MeSH descriptors assigned to MEDLINE citations for this categorization task. We compared frequencies of MeSH descriptors between two corpora applying chi-square test. A MeSH descriptor was considered to be a positive indicator if its relative observed frequency in the genetic domain corpus was greater than its relative observed frequency in the nongenetic domain corpus. The output of the proposed method is a list of scores for all the citations, with the highest score given to those citations containing MeSH descriptors typical for the genetic domain. Results: Validation was done on a set of 734 manually annotated MEDLINE citations. It achieved predictive accuracy of 0.87 with 0.69 recall and 0.64 precision. We evaluated the method by comparing it to three machine learning algorithms (support vector machines, decision trees, na\"ive Bayes). Although the differences were not statistically significantly different, results showed that our chi-square scoring performs as good as compared machine learning algorithms. Conclusions: We suggest that the chi-square scoring is an effective solution to help categorize MEDLINE citations. The algorithm is implemented in the BITOLA literature-based discovery support system as a preprocessor for gene symbol disambiguation process.Comment: 34 pages, 2 figure

All mixed up? Finding the optimal feature set for general readability prediction and its application to English and Dutch

Readability research has a long and rich tradition, but there has been too little focus on general readability prediction without targeting a specific audience or text genre. Moreover, though NLP-inspired research has focused on adding more complex readability features there is still no consensus on which features contribute most to the prediction. In this article, we investigate in close detail the feasibility of constructing a readability prediction system for English and Dutch generic text using supervised machine learning. Based on readability assessments by both experts and a crowd, we implement different types of text characteristics ranging from easy-to-compute superficial text characteristics to features requiring a deep linguistic processing, resulting in ten different feature groups. Both a regression and classification setup are investigated reflecting the two possible readability prediction tasks: scoring individual texts or comparing two texts. We show that going beyond correlation calculations for readability optimization using a wrapper-based genetic algorithm optimization approach is a promising task which provides considerable insights in which feature combinations contribute to the overall readability prediction. Since we also have gold standard information available for those features requiring deep processing we are able to investigate the true upper bound of our Dutch system. Interestingly, we will observe that the performance of our fully-automatic readability prediction pipeline is on par with the pipeline using golden deep syntactic and semantic information

Learning to Extract Keyphrases from Text

Many academic journals ask their authors to provide a list of about five to fifteen key words, to appear on the first page of each article. Since these key words are often phrases of two or more words, we prefer to call them keyphrases. There is a surprisingly wide variety of tasks for which keyphrases are useful, as we discuss in this paper. Recent commercial software, such as Microsoft?s Word 97 and Verity?s Search 97, includes algorithms that automatically extract keyphrases from documents. In this paper, we approach the problem of automatically extracting keyphrases from text as a supervised learning task. We treat a document as a set of phrases, which the learning algorithm must learn to classify as positive or negative examples of keyphrases. Our first set of experiments applies the C4.5 decision tree induction algorithm to this learning task. The second set of experiments applies the GenEx algorithm to the task. We developed the GenEx algorithm specifically for this task. The third set of experiments examines the performance of GenEx on the task of metadata generation, relative to the performance of Microsoft?s Word 97. The fourth and final set of experiments investigates the performance of GenEx on the task of highlighting, relative to Verity?s Search 97. The experimental results support the claim that a specialized learning algorithm (GenEx) can generate better keyphrases than a general-purpose learning algorithm (C4.5) and the non-learning algorithms that are used in commercial software (Word 97 and Search 97)

Automatic epilepsy detection using fractal dimensions segmentation and GP-SVM classification

Objective: The most important part of signal processing for classification is feature extraction as a mapping from original input electroencephalographic (EEG) data space to new features space with the biggest class separability value. Features are not only the most important, but also the most difficult task from the classification process as they define input data and classification quality. An ideal set of features would make the classification problem trivial. This article presents novel methods of feature extraction processing and automatic epilepsy seizure classification combining machine learning methods with genetic evolution algorithms. Methods: Classification is performed on EEG data that represent electric brain activity. At first, the signal is preprocessed with digital filtration and adaptive segmentation using fractal dimensions as the only segmentation measure. In the next step, a novel method using genetic programming (GP) combined with support vector machine (SVM) confusion matrix as fitness function weight is used to extract feature vectors compressed into lower dimension space and classify the final result into ictal or interictal epochs. Results: The final application of GP SVM method improves the discriminatory performance of a classifier by reducing feature dimensionality at the same time. Members of the GP tree structure represent the features themselves and their number is automatically decided by the compression function introduced in this paper. This novel method improves the overall performance of the SVM classification by dramatically reducing the size of input feature vector. Conclusion: According to results, the accuracy of this algorithm is very high and comparable, or even superior to other automatic detection algorithms. In combination with the great efficiency, this algorithm can be used in real-time epilepsy detection applications. From the results of the algorithm's classification, we can observe high sensitivity, specificity results, except for the Generalized Tonic Clonic Seizure (GTCS). As the next step, the optimization of the compression stage and final SVM evaluation stage is in place. More data need to be obtained on GTCS to improve the overall classification score for GTCS.Web of Science142449243

Improvement of Text Dependent Speaker Identification System Using Neuro-Genetic Hybrid Algorithm in Office Environmental Conditions

In this paper, an improved strategy for automated text dependent speaker identification system has been proposed in noisy environment. The identification process incorporates the Neuro-Genetic hybrid algorithm with cepstral based features. To remove the background noise from the source utterance, wiener filter has been used. Different speech pre-processing techniques such as start-end point detection algorithm, pre-emphasis filtering, frame blocking and windowing have been used to process the speech utterances. RCC, MFCC, ?MFCC, ??MFCC, LPC and LPCC have been used to extract the features. After feature extraction of the speech, Neuro-Genetic hybrid algorithm has been used in the learning and identification purposes. Features are extracted by using different techniques to optimize the performance of the identification. According to the VALID speech database, the highest speaker identification rate of 100.000% for studio environment and 82.33% for office environmental conditions have been achieved in the close set text dependent speaker identification system

A new unsupervised feature selection method for text clustering based on genetic algorithms

Nowadays a vast amount of textual information is collected and stored in various databases around the world, including the Internet as the largest database of all. This rapidly increasing growth of published text means that even the most avid reader cannot hope to keep up with all the reading in a field and consequently the nuggets of insight or new knowledge are at risk of languishing undiscovered in the literature. Text mining offers a solution to this problem by replacing or supplementing the human reader with automatic systems undeterred by the text explosion. It involves analyzing a large collection of documents to discover previously unknown information. Text clustering is one of the most important areas in text mining, which includes text preprocessing, dimension reduction by selecting some terms (features) and finally clustering using selected terms. Feature selection appears to be the most important step in the process. Conventional unsupervised feature selection methods define a measure of the discriminating power of terms to select proper terms from corpus. However up to now the valuation of terms in groups has not been investigated in reported works. In this paper a new and robust unsupervised feature selection approach is proposed that evaluates terms in groups. In addition a new Modified Term Variance measuring method is proposed for evaluating groups of terms. Furthermore a genetic based algorithm is designed and implemented for finding the most valuable groups of terms based on the new measure. These terms then will be utilized to generate the final feature vector for the clustering process . In order to evaluate and justify our approach the proposed method and also a conventional term variance method are implemented and tested using corpus collection Reuters-21578. For a more accurate comparison, methods have been tested on three corpuses and for each corpus clustering task has been done ten times and results are averaged. Results of comparing these two methods are very promising and show that our method produces better average accuracy and F1-measure than the conventional term variance method