A Total Fractional-Order Variation Model for Image Restoration with Non-homogeneous Boundary Conditions and its Numerical Solution

To overcome the weakness of a total variation based model for image restoration, various high order (typically second order) regularization models have been proposed and studied recently. In this paper we analyze and test a fractional-order derivative based total $\alpha$-order variation model, which can outperform the currently popular high order regularization models. There exist several previous works using total $\alpha$-order variations for image restoration; however first no analysis is done yet and second all tested formulations, differing from each other, utilize the zero Dirichlet boundary conditions which are not realistic (while non-zero boundary conditions violate definitions of fractional-order derivatives). This paper first reviews some results of fractional-order derivatives and then analyzes the theoretical properties of the proposed total $\alpha$-order variational model rigorously. It then develops four algorithms for solving the variational problem, one based on the variational Split-Bregman idea and three based on direct solution of the discretise-optimization problem. Numerical experiments show that, in terms of restoration quality and solution efficiency, the proposed model can produce highly competitive results, for smooth images, to two established high order models: the mean curvature and the total generalized variation.Comment: 26 page

Simultaneous Data Recovery in Image and Transform Domains

Master'sMASTER OF SCIENC

GPU-based Iterative Cone Beam CT Reconstruction Using Tight Frame Regularization

X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical concern in most image guided radiation therapy procedures. It is the goal of this paper to develop a fast GPU-based algorithm to reconstruct high quality CBCT images from undersampled and noisy projection data so as to lower the imaging dose. For this purpose, we have developed an iterative tight frame (TF) based CBCT reconstruction algorithm. A condition that a real CBCT image has a sparse representation under a TF basis is imposed in the iteration process as regularization to the solution. To speed up the computation, a multi-grid method is employed. Our GPU implementation has achieved high computational efficiency and a CBCT image of resolution 512\times512\times70 can be reconstructed in ~5 min. We have tested our algorithm on a digital NCAT phantom and a physical Catphan phantom. It is found that our TF-based algorithm is able to reconstrct CBCT in the context of undersampling and low mAs levels. We have also quantitatively analyzed the reconstructed CBCT image quality in terms of modulation-transfer-function and contrast-to-noise ratio under various scanning conditions. The results confirm the high CBCT image quality obtained from our TF algorithm. Moreover, our algorithm has also been validated in a real clinical context using a head-and-neck patient case. Comparisons of the developed TF algorithm and the current state-of-the-art TV algorithm have also been made in various cases studied in terms of reconstructed image quality and computation efficiency.Comment: 24 pages, 8 figures, accepted by Phys. Med. Bio