Properties of Healthcare Teaming Networks as a Function of Network Construction Algorithms

Network models of healthcare systems can be used to examine how providers collaborate, communicate, refer patients to each other. Most healthcare service network models have been constructed from patient claims data, using billing claims to link patients with providers. The data sets can be quite large, making standard methods for network construction computationally challenging and thus requiring the use of alternate construction algorithms. While these alternate methods have seen increasing use in generating healthcare networks, there is little to no literature comparing the differences in the structural properties of the generated networks. To address this issue, we compared the properties of healthcare networks constructed using different algorithms and the 2013 Medicare Part B outpatient claims data. Three different algorithms were compared: binning, sliding frame, and trace-route. Unipartite networks linking either providers or healthcare organizations by shared patients were built using each method. We found that each algorithm produced networks with substantially different topological properties. Provider networks adhered to a power law, and organization networks to a power law with exponential cutoff. Censoring networks to exclude edges with less than 11 shared patients, a common de-identification practice for healthcare network data, markedly reduced edge numbers and greatly altered measures of vertex prominence such as the betweenness centrality. We identified patterns in the distance patients travel between network providers, and most strikingly between providers in the Northeast United States and Florida. We conclude that the choice of network construction algorithm is critical for healthcare network analysis, and discuss the implications for selecting the algorithm best suited to the type of analysis to be performed.Comment: With links to comprehensive, high resolution figures and networks via figshare.co

Paving the way towards high-level parallel pattern interfaces for data stream processing

The emergence of the Internet of Things (IoT) data stream applications has posed a number of new challenges to existing infrastructures, processing engines, and programming models. In this sense, high-level interfaces, encapsulating algorithmic aspects in pattern-based constructions, have considerably reduced the development and parallelization efforts of this type of applications. An example of parallel pattern interface is GrPPI, a C++ generic high-level library that acts as a layer between developers and existing parallel programming frameworks, such as C++ threads, OpenMP and Intel TBB. In this paper, we complement the basic patterns supported by GrPPI with the new stream operators Split-Join and Window, and the advanced parallel patterns Stream-Pool, Windowed-Farm and Stream-Iterator for the aforementioned back ends. Thanks to these new stream operators, complex compositions among streaming patterns can be expressed. On the other hand, the collection of advanced patterns allows users to tackle some domain-specific applications, ranging from the evolutionary to the real-time computing areas, where compositions of basic patterns are not capable of fully mimicking the algorithmic behavior of their original sequential codes. The experimental evaluation of the new advanced patterns and the stream operators on a set of domain-specific use-cases, using different back ends and pattern-specific parameters, reports considerable performance gains with respect to the sequential versions. Additionally, we demonstrate the benefits of the GrPPI pattern interface from the usability, flexibility and readability points of view.This work was partially supported by the EU project ICT 644235 “RePhrase: REfactoring Parallel Heterogeneous Resource-Aware Applications” and the project TIN2013-41350-P “Scalable Data Management Techniques for High-End Computing Systems” from the Ministerio de Economía y Competitividad, Spai

English Bards and Unknown Reviewers: a Stylometric Analysis of Thomas Moore and the Christabel Review

Fraught relations between authors and critics are a commonplace of literary history. The particular case that we discuss in this article, a negative review of Samuel Taylor Coleridge's Christabel (1816), has an additional point of interest beyond the usual mixture of amusement and resentment that surrounds a critical rebuke: the authorship of the review remains, to this day, uncertain. The purpose of this article is to investigate the possible candidacy of Thomas Moore as the author of the provocative review. It seeks to solve a puzzle of almost two hundred years, and in the process clear a valuable scholarly path in Irish Studies, Romanticism, and in our understanding of Moore's role in a prominent literary controversy of the age

Streaming Similarity Self-Join

We introduce and study the problem of computing the similarity self-join in a streaming context (SSSJ), where the input is an unbounded stream of items arriving continuously. The goal is to find all pairs of items in the stream whose similarity is greater than a given threshold. The simplest formulation of the problem requires unbounded memory, and thus, it is intractable. To make the problem feasible, we introduce the notion of time-dependent similarity: the similarity of two items decreases with the difference in their arrival time. By leveraging the properties of this time-dependent similarity function, we design two algorithmic frameworks to solve the sssj problem. The first one, MiniBatch (MB), uses existing index-based filtering techniques for the static version of the problem, and combines them in a pipeline. The second framework, Streaming (STR), adds time filtering to the existing indexes, and integrates new time-based bounds deeply in the working of the algorithms. We also introduce a new indexing technique (L2), which is based on an existing state-of-the-art indexing technique (L2AP), but is optimized for the streaming case. Extensive experiments show that the STR algorithm, when instantiated with the L2 index, is the most scalable option across a wide array of datasets and parameters

Mixing Bandt-Pompe and Lempel-Ziv approaches: another way to analyze the complexity of continuous-states sequences

In this paper, we propose to mix the approach underlying Bandt-Pompe permutation entropy with Lempel-Ziv complexity, to design what we call Lempel-Ziv permutation complexity. The principle consists of two steps: (i) transformation of a continuous-state series that is intrinsically multivariate or arises from embedding into a sequence of permutation vectors, where the components are the positions of the components of the initial vector when re-arranged; (ii) performing the Lempel-Ziv complexity for this series of `symbols', as part of a discrete finite-size alphabet. On the one hand, the permutation entropy of Bandt-Pompe aims at the study of the entropy of such a sequence; i.e., the entropy of patterns in a sequence (e.g., local increases or decreases). On the other hand, the Lempel-Ziv complexity of a discrete-state sequence aims at the study of the temporal organization of the symbols (i.e., the rate of compressibility of the sequence). Thus, the Lempel-Ziv permutation complexity aims to take advantage of both of these methods. The potential from such a combined approach - of a permutation procedure and a complexity analysis - is evaluated through the illustration of some simulated data and some real data. In both cases, we compare the individual approaches and the combined approach.Comment: 30 pages, 4 figure