5,966 research outputs found
Technology, global value chains and functional specialisation in Europe
This paper provides empirical evidence on the role of technology in affecting the relationship between the participation of EU countries and industries in Global Value Chains (GVCs) and their employment structure over the period 2000–2014. The empirical analysis is based on country-sector level data for 21 EU countries on employment, trade in value added, patents and investments in intangible assets, and focusses on backward linkages within GVCs. The role of technology is analysed by taking into account both the technological intensity of country-sectors participating in GVC and that of their GVC partners. We study the employment structure by looking at the shares of managers and manual workers, which reflect the “functional specialisation” of the country-sector within GVCs. We find that participation in GVC per se is not related to the employment structure of a country-sector. We show that different patterns of GVC integration and functional specialisation emerge that depend on the initial patents/intangibles intensity of the country-sector integrating in GVC and those of the partners
Physiological responses and cognitive behaviours: Measures of heart rate variability index language knowledge
Over the past decades, focus has been on developing methods that allow tapping into aspects of cognition that are not directly observable. This includes linguistic knowledge and skills which develop largely without awareness and may therefore be difficult or impossible to articulate. Building on the relation between language cognition and the nervous system, we examine whether Heart Rate Variability (HRV), a cardiovascular measure that indexes Autonomic Nervous System activity, can be used to assess implicit language knowledge. We test the potential of HRV to detect whether individuals possess grammatical knowledge and explore how sensitive the cardiovascular response is.
41 healthy, British English-speaking adults listened to 40 English speech samples, half of which contained grammatical errors. Thought Technology's 5-channel ProComp 5 encoder tracked heart rate via a BVP-Flex/Pro sensor attached to the middle finger of the non-dominant hand, at a rate of 2048 samples per second. A Generalised Additive Mixed Effects Model confirmed a cardiovascular response to grammatical violations: there is a statistically significant reduction in HRV as indexed by NN50 in response to stimuli that contain errors. The cardiovascular response reflects the extent of the linguistic violations, and NN50 decreases linearly with an increase in the number of errors, up to a certain level, after which HRV remains constant.
This observation brings into focus a new dimension of the intricate relationship between physiology and cognition. Being able to use a highly portable and non-intrusive technique with language stimuli also creates exciting possibilities for assessing the language knowledge of individuals from a range of populations in their natural environment and in authentic communicative situations
Sports Heart Monitors as Reliable Diagnostic Tools for Training Control and Detecting Arrhythmias in Professional and Leisure-Time Endurance Athletes: An Expert Consensus Statement
There are countless types of portable heart rate monitoring medical devices used variously by leisure-time exercisers, professional athletes, and chronically ill patients. Almost all the currently used heart rate monitors are capable of detecting arrhythmias, but this feature is not widely known or used among their millions of consumers. The aims of this paper were as follows: (1) to analyze the currently available sports heart rate monitors and assess their advantages and disadvantage in terms of heart rate and rhythm monitoring in endurance athletes; (2) to discuss what types of currently available commercial heart rate monitors are most convenient/adjustable to the needs of different consumers (including occasionally physically active adults and cardiac patients), bearing in mind the potential health risks, especially heart rhythm disturbances connected with endurance training; (3) to suggest a set of "optimal" design features for next-generation smart wearable devices based on the consensus opinion of an expert panel of athletes, coaches, and sports medicine doctors. Ninety-two experts aged 20 years and over, involved in endurance sports on a daily basis, were invited to participate in consensus-building discussions, including 56 long-distance runners, 18 cyclists, nine coaches, and nine physicians (sports medicine specialists, cardiologists, and family medicine doctors). The overall consensus endorsed by these experts indicates that the "optimal" sports heart rate monitor should be a one-piece device of the smartwatch type (with two or more electrodes), with integrated smartphone features, and able to collect and continually transmit data without exhibiting artifacts. It should continuously record at least a single-lead electrocardiography, send an alert after an unexpected fall, be of reasonable weight, come at an affordable price, and be user friendly
Characterization of viral infections in children with influenza-like-illness during December 2018–January 2019
IntroductionRespiratory viral infection (RVI) is of very concern after the outbreak of COVID-19, especially in pediatric departments. Learning pathogen spectrum of RVI in children previous the epidemic of COVID-19 could provide another perspective for understanding RVI under current situation and help to prepare for the post COVID-19 infection control.MethodsA nucleic acid sequence-based amplification (NASBA) assay, with 19 pairs of primers targeting various respiratory viruses, was used for multi-pathogen screening of viral infections in children presenting influenza-like illness (ILI) symptoms. Children with ILI at the outpatient department of Beijing Tsinghua Changgung Hospital during the influenza epidemic from 12/2018 to 01/2019 were included. Throat swabs were obtained for both the influenza rapid diagnostic test (IRDT) based on the colloidal gold immunochromatographic assay and the NASBA assay, targeting various respiratory viruses with an integrated chip technology.Results and discussionOf 519 patients, 430 (82.9%) were positive in the NASBA assay. The predominant viral pathogens were influenza A H1N1 pdm1/2009 (pH1N1) (48.4%) and influenza A (H3N2) (18.1%), followed by human metapneumovirus (hMPV) (8.8%) and respiratory syncytial virus (RSV) (6.1%). Of the 320 cases identified with influenza A by NASBA, only 128 (40.0%) were positive in the IRDT. The IRDT missed pH1N1 significantly more frequently than A (H3N2) (P<0.01). Influenza A pH1N1 and A (H3N2) were the major pathogens in <6 years and 6-15 years old individuals respectively (P<0.05). In summary, influenza viruses were the major pathogens in children with ILI during the 2018-2019 winter influenza epidemic, while hMPV and RSV were non-negligible. The coexistence of multiple pathogen leading to respiratory infections is the normalcy in winter ILI cases
Behavioral observations, heart rate and cortisol monitoring in horses following multiple oral administrations of a cannabidiol containing paste (part 2/2)
As a remedy against stress and anxiety, cannabidiol (CBD) products are of increasing interest in veterinary medicine. Limited data is available describing the actual effectiveness of CBD in horses. The aim of this study (part 2 of 2) was to analyze stress parameters via behavioral observation, heart rate monitoring and assessment of blood and saliva cortisol levels in healthy horses treated repeatedly with a CBD containing paste. Twelve horses were randomly assigned to a treatment or a control group. Two pastes were orally administered in a double-blinded study design, one paste containing CBD and one paste without active ingredient. Both pastes were administered twice daily over 15 days (dose: 3 mg CBD/kg). Behavioral observations were conducted daily using a sedation score and a rating of facial expressions, based on the previously described facial sedation scale for horses (FaceSed) and the Horse Grimace Scale. Blood and saliva samples were obtained regularly to determine cortisol levels throughout the study. Cortisol levels were analyzed by means of liquid chromatography/tandem mass spectrometry (LC/MS/MS). Behavioral observations and cortisol levels were compared between groups. Prior to paste administration, a novel object test was performed and the horses’ reaction to loading on a trailer was recorded. Both tests were repeated after 13 days of paste application. Movement patterns such as different gaits during the novel object test were evaluated and an ethogram was designed to assess exhibited behavioral traits. Cardiac beat-to-beat (R-R) intervals were recorded throughout and evaluated using heart rate (HR) and heart rate variability (HRV) parameters. Blood and saliva samples for cortisol analysis were taken before and after the tests. Daily behavioral observations and cortisol levels did not differ between the treatment and the control group. Similarly, analysis of movement patterns, HR, HRV and cortisol levels during the novel object test and trailer test did not identify significant differences between the groups. Regularly administered oral CBD (3 mg/kg BID over 15 days) had no statistically significant effect on behavioral observations, cortisol levels, HR and HRV in horses. Further research is required to establish adequate doses and indications for the use of CBD in horses
Study of stress detection and proposal of stress-related features using commercial-off-the-shelf wrist wearables
This paper discusses the possibility of detecting personal stress making use of popular wearable devices available in the market. Different instruments found in the literature to measure stress-related features are reviewed, distinguishing between subjective tests and mechanisms supported by the analysis of physiological signals from clinical devices. Taking them as a reference, a solution to estimate stress based on the use of commercial-off-the-shelf wrist wearables and machine learning techniques is described. A mobile app was developed to induce stress in a uniform and systematic way. The app implements well-known stress inducers, such as the Paced Auditory Serial Addition Test, the Stroop Color-Word Interference Test, and a hyperventilation activity. Wearables are used to collect physiological data used to train classifiers that provide estimations on personal stress levels. The solution has been validated in an experiment involving 19 subjects, offering an average accuracy and F-measures close to 0.99 in an individual model and an accuracy and F-measure close to 0.85 in a global 2-level classifier model. Stress can be a worrying problem in different scenarios, such as in educational settings. Thus, the last part of the paper describes the proposal of a set of stress related indicators aimed to support the management of stress over time in such settings.Agencia Estatal de Investigación | Ref. TIN2016-80515-RUniversidade de Vig
Enhancing the Quality of Life for Senior Citizens: A Facilitator’s Guidebook for Mindful Music and Movement
Music appreciation and enjoyment enhance well-being throughout the lifespan. The challenges and constraints that people experience as they age can lead to lack of access to music, decreased physical activity, and fewer avenues for creative expression. Group music and movement interventions created for older populations offer opportunities for social connection and improved quality of life. Mindful practices add further benefit when combined with these interventions. Current available programs are scarce and most often do not encompass mixed modalities. In addition, the benefits of these programs do not show long-term sustainability. The purpose of this thesis is to explore the effects of music, movement, and mindfulness on overall health and present a program that helps establish and maintain well-being for senior citizens
Relationship Between Substance Use, Alcohol, and Posttraumatic Stress Disorder Symptoms in Law Enforcement
Law enforcement officers are plagued by a variety of traumatic incidents and organizational stressors. As a result, officers are more likely to use maladaptive coping skills and develop stress-related disorders. The purpose of this study was to identify the predictive relationship between substance use, alcohol use, and posttraumatic stress symptoms (PTSS)/dissociation symptoms in 107 law enforcement officers using the Personal Observation Wellness and Evaluation Report- POWER Portfolio survey through an archival dataset. Lazurus and Folkman’s transactional model of stress and coping was used for the theoretical understanding of the current study. The independent variable for this study was PTSS as measured by the Dissociation/PTSD scale of the POWER Portfolio survey. The dependent variables for this study included substance abuse and alcohol use as measured by the Substance Use scale of the POWER Portfolio survey. Two simple regression analyses were used to identify any predictive relationships between PTSS, alcohol use, and substance use. Data used in this study were archival data provided by a nonprofit company. The results of this study indicated a statistically significant relationship between PTSS, alcohol use, and substance use. While this does not indicate causality, it does indicate the officers’ PTSS were likely to impact their use of substances and alcohol. Implications for positive social change include the development and access to mental health services and programs, focusing not only on PTSS but on substance use and other mental health disorders for law enforcement officers
The association between pre-operative pain experience and post-operative pain in patients undergoing elective gastrointestinal surgery: a descriptive-comparative study
Aims: The purpose of the rapid review was to summarize and aggregate information for researchers and clinicians about predisposing factors for post-operative pain in laparoscopic patients and the prevalent management approaches post-operatively. The purpose of the descriptive-comparative study was to explore the associations between previous pain experiences and medication on the intensity of pain post-operatively in patients undergoing elective gastrointestinal surgery, using data collected by the Smart Pain Assessment Tool Based on Internet of Things.
Methods: For the rapid review, the databases of PubMed, Web of Science and Embase were searched. ROBINS-I tool was used to evaluate the quality of non-randomized studies while ROB 2 tool was used for randomized controlled trials. For the descriptive-comparative study, 50 patients after gastrointestinal operations at Turku University hospital were included. The data collection of the study was done by a researcher belonging to Turku University staff at Turku University hospital. The data analysis was done by using descriptive and comparative methods of analysis. Descriptive statistics were used for the presentation and analysis of participants outcomes, diagnoses, procedures, and groupings based on variables related to the experience of pain (e.g., graphical measurement maximal pain levels using the numeric rating scale). Comparative statistics were used for associations and correlations regarding previous pain levels, medications, fear, and expectation of pain on maximal pain levels after gastrointestinal operations at Turku University Hospital.
Results: The result of the rapid review suggest many predisposing factors for post-operative pain are influenced by the psychological profile of the patient. Among these factors are anxiety, fear, depression, expectation of pain, and other factors related to gastrointestinal surgery. Nevertheless, the results of this review also describe acute pre-operative pain, surgical factors, genetics, age, gender, obesity, and previous experiences of pain as relevant predisposing factors to pain following gastrointestinal surgery. Pain care strategies following gastrointestinal surgery include the use of pharmacological and non-pharmacological interventions. The literature suggests, non-pharmacological interventions are under-utilized and should be encouraged as an adjunct to pharmacological pain control strategies following elective gastrointestinal surgery.
The results of the descriptive-comparative study somewhat contradict the results of the rapid review. Previous pain experiences or the recollection of preceding painful events were not associated with the administration of supplemental pain medication post-operatively (p = 0.741). Fear related to the upcoming pain following surgery was not associated with the level of invasiveness of the surgery (p = 0.662). In addition, the relationship between expectation of pain (p = 0.698), fear of pain related to the upcoming surgical procedure (p = 0.637) and medication post-operatively (p = .481) on the intensity of maximal post-operative pain was found to be negligible. The results of this study suggest patient expectation as a possible domain of intervention for better pain outcomes post-operatively. The administration of pain medication in the recovery room and the amount of pain medication in the recovery room were significant predictors of maximal post-operative pain (p = .001).
Discussion: The results of the rapid review suggest a high to critical risk of bias in the studies included. The predisposing factors for post-operative pain differed widely across studies, but mainly included psychological factors as factors for post-operative pain. Pain management strategies should include an individualized approach and be implemented before, during and after the operation. For the descriptive-comparative study, there are substantial difficulties in discerning the effect of pain history or experience on post-operative pain using physiological or subjective reporting for conscious individuals due to risk of bias and using a unidimensional approach.
Conclusion: Predisposing factors for post-operative pain should be screened in the pre-operative phase if possible, focusing on addressable factors whereas management of pain care strategies should include careful screening of participants biopsychosocial profile for elective surgery. The descriptive-comparative study suggests a possible, yet minimal benefit for managing patients’ expectation of pain related to the upcoming gastrointestinal surgery. The amount of pain medication in the recovery room is a significant predictor of maximal post-operative pain. Future research should include a larger sample, more variables related to pain and continue with a follow-up.
Keywords: gastrointestinal, post-operative, pain, analgesia, anesthesiaTavoitteet: Katsauksen tarkoituksena oli tiivistää ja koota yhteen tutkijoille ja kliinikoille tietoa laparoskooppisten potilaiden postoperatiiviselle kivulle altistavista tekijöistä ja vallitsevista postoperatiivisista hoitokeinoista. Kuvailevan-vertailevan tutkimuksen tarkoituksena oli tutkia aiempien kipukokemusten ja lääkityksen välisiä yhteyksiä postoperatiivisen kivun voimakkuuteen potilailla, joille tehdään elektiivinen ruoansulatuskanavan leikkaus, käyttäen tietoja, jotka on kerätty esineiden internetiin perustuvalla älykkäällä kivunarviointityökalulla.
Menetelmät: Katsausta varten tehtiin hakuja PubMed-, Web of Science- ja Embase-tietokannoista. ROBINS-I-työkalua käytettiin satunnaistamattomien tutkimusten laadun arviointiin, kun taas satunnaistettujen kontrolloitujen tutkimusten osalta käytettiin ROB 2-työkalua. Kuvailevaan-vertailevaan tutkimukseen otettiin mukaan 50 potilasta Turun yliopistollisessa sairaalassa tehtyjen ruoansulatuskanavan leikkausten jälkeen. Tutkimuksen aineistonkeruun suoritti Turun yliopiston henkilökuntaan kuuluva tutkija Turun yliopistollisessa sairaalassa. Aineiston analysoinnissa käytettiin kuvailevia ja vertailevia analyysimenetelmiä. Kuvailevia tilastoja käytettiin osallistujien tulosten, diagnoosien, toimenpiteiden ja kivun kokemiseen liittyvien muuttujien perusteella tehtyjen ryhmittelyjen esittämiseen ja analysointiin (esim. maksimaalisen kiputason graafinen mittaaminen numeerisella arviointiasteikolla). Vertailevia tilastoja käytettiin yhdistelmiin ja korrelaatioihin, jotka koskivat aiempia kiputiloja, lääkkeitä, pelkoa ja kivun odotusta maksimaalisen kiputason suhteen ruoansulatuskanavan leikkausten jälkeen Turun yliopistollisessa sairaalassa.
Tulokset: Katsauksen tulokset viittaavat siihen, että potilaan psykologinen profiili vaikuttaa moniin leikkauksen jälkeiselle kivulle altistaviin tekijöihin. Näihin tekijöihin kuuluvat ahdistus, pelko, masennus, kivun odotus ja muut ruoansulatuskanavan leikkaukseen liittyvät tekijät. Tämän katsauksen tuloksissa kuvataan kuitenkin myös akuutti preoperatiivinen kipu, kirurgiset tekijät, genetiikka, ikä, sukupuoli, lihavuus ja aiemmat kokemukset kivusta merkityksellisinä altistavina tekijöinä ruoansulatuskanavan leikkauksen jälkeiselle kivulle. Ruoansulatuskanavan leikkauksen jälkeisiin kivunhoitostrategioihin kuuluu farmakologisten ja ei-farmakologisten toimenpiteiden käyttö. Kirjallisuuden mukaan ei-farmakologisia toimenpiteitä käytetään liian vähän, ja niitä olisi edistettävä farmakologisten kivunhoitostrategioiden lisänä elektiivisen ruoansulatuskanavan leikkauksen jälkeen.
Kuvailevan ja vertailevan tutkimuksen tulokset ovat jossain määrin ristiriidassa nopean katsauksen tulosten kanssa. Aiemmat kipukokemukset tai aiempien kivuliaiden tapahtumien muistaminen eivät olleet yhteydessä ylimääräisen kipulääkityksen antamiseen leikkauksen jälkeen (p = 0,741). Leikkauksen jälkeiseen tulevaan kipuun liittyvä pelko ei ollut yhteydessä leikkauksen invasiivisuuteen (p = 0,662). Lisäksi kivun odotuksen (p = 0,698), tulevaan kirurgiseen toimenpiteeseen liittyvän kivun pelon (p = 0,637) ja leikkauksen jälkeisen lääkityksen (p = 0,481) välinen yhteys maksimaalisen leikkauksen jälkeisen kivun voimakkuuteen todettiin merkityksettömäksi. Tämän tutkimuksen tulokset viittaavat siihen, että potilaan odotukset ovat mahdollinen interventioalue, jolla voidaan parantaa leikkauksen jälkeistä kiputilannetta. Kipulääkityksen antaminen heräämössä ja kipulääkityksen määrä heräämössä olivat merkittäviä postoperatiivisen maksimaalisen kivun ennustajia (p = .001).
Pohdinta: Katsauksen tulokset viittaavat siihen, että mukana olleissa tutkimuksissa on suuri tai kriittinen harhan riski. Postoperatiiviselle kivulle altistavat tekijät vaihtelivat suuresti eri tutkimuksissa, mutta niihin sisältyi pääasiassa psykologisia tekijöitä postoperatiivisen kivun tekijöinä. Kivunhoitostrategioihin olisi sisällyttävä yksilöllinen lähestymistapa, ja niitä olisi sovellettava ennen leikkausta, sen aikana ja sen jälkeen. Kuvailevassa ja vertailevassa tutkimuksessa on huomattavia vaikeuksia havaita kipuhistorian tai -kokemuksen vaikutusta leikkauksen jälkeiseen kipuun fysiologisen tai subjektiivisen raportoinnin avulla tietoisten yksilöiden osalta, koska on olemassa harhan riski ja koska käytetään yksiulotteista lähestymistapaa.
Johtopäätökset: Kivunhoitostrategioihin olisi kuuluttava osallistujien biopsykososiaalisen profiilin huolellinen seulonta valintaleikkausta varten. Kuvaileva-vertaileva tutkimus viittaa siihen, että potilaiden tulevaan ruoansulatuskanavan leikkaukseen liittyvien kipuodotusten hallinnasta on mahdollista, joskin vähäistä hyötyä. Kipulääkkeiden määrä heräämössä on merkittävä leikkauksen jälkeisen maksimaalisen kivun ennustaja. Tulevaan tutkimukseen olisi sisällytettävä suurempi otos, enemmän kipuun liittyviä muuttujia ja jatkettava seurantaa
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