Clinical Decision Support for Integrated Cyber-Physical Systems: A Mixed Methods Approach

We describe the design and implementation of a clinical decision support system for assessing risk of cerebral vasospasm in patients who have been treated for aneurysmal subarachnoid hemorrhage. We illustrate the need for such clinical decision support systems in the intensive care environment, and propose a three pronged approach to constructing them, which we believe presents a balanced approach to patient modeling. We illustrate the data collection process, choice and development of models, system architecture, and methodology for user interface design. We close with a description of future work, a proposed evaluation mechanism, and a description of the demo to be presented

Ensuring patients privacy in a cryptographic-based-electronic health records using bio-cryptography

Several recent works have proposed and implemented cryptography as a means to preserve privacy and security of patients health data. Nevertheless, the weakest point of electronic health record (EHR) systems that relied on these cryptographic schemes is key management. Thus, this paper presents the development of privacy and security system for cryptography-based-EHR by taking advantage of the uniqueness of fingerprint and iris characteristic features to secure cryptographic keys in a bio-cryptography framework. The results of the system evaluation showed significant improvements in terms of time efficiency of this approach to cryptographic-based-EHR. Both the fuzzy vault and fuzzy commitment demonstrated false acceptance rate (FAR) of 0%, which reduces the likelihood of imposters gaining successful access to the keys protecting patients protected health information. This result also justifies the feasibility of implementing fuzzy key binding scheme in real applications, especially fuzzy vault which demonstrated a better performance during key reconstruction

Temporal expression normalisation in natural language texts

Automatic annotation of temporal expressions is a research challenge of great interest in the field of information extraction. In this report, I describe a novel rule-based architecture, built on top of a pre-existing system, which is able to normalise temporal expressions detected in English texts. Gold standard temporally-annotated resources are limited in size and this makes research difficult. The proposed system outperforms the state-of-the-art systems with respect to TempEval-2 Shared Task (value attribute) and achieves substantially better results with respect to the pre-existing system on top of which it has been developed. I will also introduce a new free corpus consisting of 2822 unique annotated temporal expressions. Both the corpus and the system are freely available on-line.Comment: 7 pages, 1 figure, 5 table

On the Use of Time Series Kernel and Dimensionality Reduction to Identify the Acquisition of Antimicrobial Multidrug Resistance in the Intensive Care Unit

Presentation at the 2021 KDD Workshop on Applied Data Science for Healthcare, 15.08.21 - 16.08.21. https://dshealthkdd.github.io/dshealth-2021/The acquisition of Antimicrobial Multidrug Resistance (AMR) in patients admitted to the Intensive Care Units (ICU) is a major global concern. This study analyses data in the form of multivariate time series (MTS) from 3476 patients recorded at the ICU of University Hospital of Fuenlabrada (Madrid) from 2004 to 2020. 18% of the patients acquired AMR during their stay in the ICU. The goal of this paper is an early prediction of the development of AMR. Towards that end, we leverage the time-series cluster kernel (TCK) to learn similarities between MTS. To evaluate the effectiveness of TCK as a kernel, we applied several dimensionality reduction techniques for visualization and classification tasks. The experimental results show that TCK allows identifying a group of patients that acquire the AMR during the first 48 hours of their ICU stay, and it also provides good classification capabilities