An improvement in support vector machine classification model using grey relational analysis for cancer diagnosis

To further improve the accuracy of classifier for cancer diagnosis, a hybrid model called GRA-SVM which comprises Support Vector Machine classifier and filter feature selection Grey Relational Analysis is proposed and tested against Wisconsin Breast Cancer Dataset (WBCD) and BUPA Disorder Dataset. The performance of GRA-SVM is compared to SVM’s in terms of accuracy, sensitivity, specificity and Area under Curve (AUC). The experimental results reveal that GRA-SVM improves the SVM accuracy of about 0.48 by using only two features for the WBCD dataset. For BUPA dataset, GRA-SVM improves the SVM accuracy of about 0.97 by using four features. Besides improving the accuracy performance, GRA-SVM also produces a ranking scheme that provides information about the priority of each feature. Therefore, based on the benefits gained, GRA-SVM is recommended as a new approach to obtain a better and more accurate result for cancer diagnosis

A New Hybrid Breast Cancer Diagnosis Model Using Deep Learning Model and ReliefF

Breast cancer is a dangerous type of cancer usually found in women and is a significant research topic in medical science. In patients who are diagnosed and not treated early, cancer spreads to other organs, making treatment difficult. In breast cancer diagnosis, the accuracy of the pathological diagnosis is of great importance to shorten the decision-making process, minimize unnoticed cancer cells and obtain a faster diagnosis. However, the similarity of images in histopathological breast cancer image analysis is a sensitive and difficult process that requires high competence for field experts. In recent years, researchers have been seeking solutions to this process using machine learning and deep learning methods, which have contributed to significant developments in medical diagnosis and image analysis. In this study, a hybrid DCNN + ReliefF is proposed for the classification of breast cancer histopathological images, utilizing the activation properties of pre-trained deep convolutional neural network (DCNN) models, and the dimension-reduction-based ReliefF feature selective algorithm. The model is based on a fine-tuned transfer-learning technique for fully connected layers. In addition, the models were compared to the k-nearest neighbor (kNN), naive Bayes (NB), and support vector machine (SVM) machine learning approaches. The performance of each feature extractor and classifier combination was analyzed using the sensitivity, precision, F1-Score, and ROC curves. The proposed hybrid model was trained separately at different magnifications using the BreakHis dataset. The results show that the model is an efficient classification model with up to 97.8% (AUC) accuracy. © 2022 Lavoisier. All rights reserved

A Cost Sensitive SVM and Neural Network Ensemble Model for Breast Cancer Classification

Breast Cancer has surpassed all categories of cancer in incidence and is the most prevalent form of cancer in women worldwide. The global incidence rate is seen to be highest in the country of Belgium as per statistics of WHO. In the case of developing countries specifically, India, it has overtaken other cancers and stands first in incidence and mortality. Major factors identified as impacting the prognosis and survival in the country is chiefly the late diagnosis of the disease and diverse situations prevailing in different parts of the country including lack of diagnostic facilities, lack of awareness, fear of undergoing existing procedures and so on. This is also true for many other countries in the world. Early diagnosis is a vital factor for survival. The implementation of machine learning techniques in cancer prediction, diagnosis and classification can assist medical practitioners as a supplementary diagnostic tool. In this work, an ensemble model of a polynomial kernel-based Support Vector machines and Gradient Descent with Momentum Back Propagation Artificial Neural Networks for Breast Cancer Classification is proposed. Feature selection is applied using Genetic Search for identifying the best feature set and data sampling techniques such as combination of oversampling and undersampling and cost senstivke learning are applied on the individual Neural Network and Support Vector Machine classifiers to deal with issues related with class imbalance. The ensemble model is seen to show superior performance in comparison with other models producing an accuracy of 99.12%

Support vector machine for optical diagnosis of cancer

We report the application of a support vector machine (SVM) for the development of diagnostic algorithms for optical diagnosis of cancer. Both linear and nonlinear SVMs have been investigated for this purpose. We develop a methodology that makes use of SVM for both feature extraction and classification jointly by integrating the newly developed recursive feature elimination (RFE) in the framework of SVM. This leads to significantly improved classification results compared to those obtained when an independent feature extractor such as principal component analysis (PCA) is used. The integrated SVM-RFE approach is also found to outperform the classification results yielded by traditional Fisher's linear discriminant (FLD)-based algorithms. All the algorithms are developed using spectral data acquired in a clinical in vivo laser-induced fluorescence (LIF) spectroscopic study conducted on patients being screened for cancer of the oral cavity and normal volunteers. The best sensitivity and specificity values provided by the nonlinear SVM-RFE algorithm over the data sets investigated are 95 and 96% toward cancer for the training set data based on leave-one-out cross validation and 93 and 97% toward cancer for the independent validation set data. When tested on the spectral data of the uninvolved oral cavity sites from the patients it yielded a specificity of 85%