A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Deep Learning Paradigms for Existing and Imminent Lung Diseases Detection: A Review

Diagnosis of lung diseases like asthma, chronic obstructive pulmonary disease, tuberculosis, cancer, etc., by clinicians rely on images taken through various means like X-ray and MRI. Deep Learning (DL) paradigm has magnified growth in the medical image field in current years. With the advancement of DL, lung diseases in medical images can be efficiently identified and classified. For example, DL can detect lung cancer with an accuracy of 99.49% in supervised models and 95.3% in unsupervised models. The deep learning models can extract unattended features that can be effortlessly combined into the DL network architecture for better medical image examination of one or two lung diseases. In this review article, effective techniques are reviewed under the elementary DL models, viz. supervised, semi-supervised, and unsupervised Learning to represent the growth of DL in lung disease detection with lesser human intervention. Recent techniques are added to understand the paradigm shift and future research prospects. All three techniques used Computed Tomography (C.T.) images datasets till 2019, but after the pandemic period, chest radiographs (X-rays) datasets are more commonly used. X-rays help in the economically early detection of lung diseases that will save lives by providing early treatment. Each DL model focuses on identifying a few features of lung diseases. Researchers can explore the DL to automate the detection of more lung diseases through a standard system using datasets of X-ray images. Unsupervised DL has been extended from detection to prediction of lung diseases, which is a critical milestone to seek out the odds of lung sickness before it happens. Researchers can work on more prediction models identifying the severity stages of multiple lung diseases to reduce mortality rates and the associated cost. The review article aims to help researchers explore Deep Learning systems that can efficiently identify and predict lung diseases at enhanced accuracy

Learning Algorithms for Fat Quantification and Tumor Characterization

Obesity is one of the most prevalent health conditions. About 30% of the world\u27s and over 70% of the United States\u27 adult populations are either overweight or obese, causing an increased risk for cardiovascular diseases, diabetes, and certain types of cancer. Among all cancers, lung cancer is the leading cause of death, whereas pancreatic cancer has the poorest prognosis among all major cancers. Early diagnosis of these cancers can save lives. This dissertation contributes towards the development of computer-aided diagnosis tools in order to aid clinicians in establishing the quantitative relationship between obesity and cancers. With respect to obesity and metabolism, in the first part of the dissertation, we specifically focus on the segmentation and quantification of white and brown adipose tissue. For cancer diagnosis, we perform analysis on two important cases: lung cancer and Intraductal Papillary Mucinous Neoplasm (IPMN), a precursor to pancreatic cancer. This dissertation proposes an automatic body region detection method trained with only a single example. Then a new fat quantification approach is proposed which is based on geometric and appearance characteristics. For the segmentation of brown fat, a PET-guided CT co-segmentation method is presented. With different variants of Convolutional Neural Networks (CNN), supervised learning strategies are proposed for the automatic diagnosis of lung nodules and IPMN. In order to address the unavailability of a large number of labeled examples required for training, unsupervised learning approaches for cancer diagnosis without explicit labeling are proposed. We evaluate our proposed approaches (both supervised and unsupervised) on two different tumor diagnosis challenges: lung and pancreas with 1018 CT and 171 MRI scans respectively. The proposed segmentation, quantification and diagnosis approaches explore the important adiposity-cancer association and help pave the way towards improved diagnostic decision making in routine clinical practice