6,961 research outputs found
Learning Tasks for Multitask Learning: Heterogenous Patient Populations in the ICU
Machine learning approaches have been effective in predicting adverse
outcomes in different clinical settings. These models are often developed and
evaluated on datasets with heterogeneous patient populations. However, good
predictive performance on the aggregate population does not imply good
performance for specific groups.
In this work, we present a two-step framework to 1) learn relevant patient
subgroups, and 2) predict an outcome for separate patient populations in a
multi-task framework, where each population is a separate task. We demonstrate
how to discover relevant groups in an unsupervised way with a
sequence-to-sequence autoencoder. We show that using these groups in a
multi-task framework leads to better predictive performance of in-hospital
mortality both across groups and overall. We also highlight the need for more
granular evaluation of performance when dealing with heterogeneous populations.Comment: KDD 201
Processing of Electronic Health Records using Deep Learning: A review
Availability of large amount of clinical data is opening up new research
avenues in a number of fields. An exciting field in this respect is healthcare,
where secondary use of healthcare data is beginning to revolutionize
healthcare. Except for availability of Big Data, both medical data from
healthcare institutions (such as EMR data) and data generated from health and
wellbeing devices (such as personal trackers), a significant contribution to
this trend is also being made by recent advances on machine learning,
specifically deep learning algorithms
Combining semantic web technologies with evolving fuzzy classifier eClass for EHR-based phenotyping : a feasibility study
In parallel to nation-wide efforts for setting up shared electronic health records (EHRs) across healthcare settings, several large-scale national and international projects are developing, validating, and deploying electronic EHR oriented phenotype algorithms that aim at large-scale use of EHRs data for genomic studies. A current bottleneck in using EHRs data for obtaining computable phenotypes is to transform the raw EHR data into clinically relevant features. The research study presented here proposes a novel combination of Semantic Web technologies with the on-line evolving fuzzy classifier eClass to
obtain and validate EHR-driven computable phenotypes derived from 1956 clinical statements from EHRs. The evaluation performed with clinicians demonstrates the feasibility and practical acceptability of the approach proposed
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