10,842 research outputs found
A novel R-package graphic user interface for the analysis of metabonomic profiles
Background Analysis of the plethora of metabolites found in the NMR spectra of biological fluids or tissues requires data complexity to be simplified. We present a graphical user interface (GUI) for NMR-based metabonomic analysis. The "Metabonomic Package" has been developed for metabonomics research as open-source software and uses the R statistical libraries. /Results The package offers the following options: Raw 1-dimensional spectra processing: phase, baseline correction and normalization. Importing processed spectra. Including/excluding spectral ranges, optional binning and bucketing, detection and alignment of peaks. Sorting of metabolites based on their ability to discriminate, metabolite selection, and outlier identification. Multivariate unsupervised analysis: principal components analysis (PCA). Multivariate supervised analysis: partial least squares (PLS), linear discriminant analysis (LDA), k-nearest neighbor classification. Neural networks. Visualization and overlapping of spectra. Plot values of the chemical shift position for different samples. Furthermore, the "Metabonomic" GUI includes a console to enable other kinds of analyses and to take advantage of all R statistical tools. /Conclusion We made complex multivariate analysis user-friendly for both experienced and novice users, which could help to expand the use of NMR-based metabonomics
Unsupervised Adaptive Re-identification in Open World Dynamic Camera Networks
Person re-identification is an open and challenging problem in computer
vision. Existing approaches have concentrated on either designing the best
feature representation or learning optimal matching metrics in a static setting
where the number of cameras are fixed in a network. Most approaches have
neglected the dynamic and open world nature of the re-identification problem,
where a new camera may be temporarily inserted into an existing system to get
additional information. To address such a novel and very practical problem, we
propose an unsupervised adaptation scheme for re-identification models in a
dynamic camera network. First, we formulate a domain perceptive
re-identification method based on geodesic flow kernel that can effectively
find the best source camera (already installed) to adapt with a newly
introduced target camera, without requiring a very expensive training phase.
Second, we introduce a transitive inference algorithm for re-identification
that can exploit the information from best source camera to improve the
accuracy across other camera pairs in a network of multiple cameras. Extensive
experiments on four benchmark datasets demonstrate that the proposed approach
significantly outperforms the state-of-the-art unsupervised learning based
alternatives whilst being extremely efficient to compute.Comment: CVPR 2017 Spotligh
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