Data-driven modelling of biological multi-scale processes

Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales. In this manuscript we review mathematical modelling approaches used to describe the individual spatial scales and how they are integrated into holistic models. We discuss the relation between spatial and temporal scales and the implication of that on multi-scale modelling. Based upon this overview over state-of-the-art modelling approaches, we formulate key challenges in mathematical and computational modelling of biological multi-scale and multi-physics processes. In particular, we considered the availability of analysis tools for multi-scale models and model-based multi-scale data integration. We provide a compact review of methods for model-based data integration and model-based hypothesis testing. Furthermore, novel approaches and recent trends are discussed, including computation time reduction using reduced order and surrogate models, which contribute to the solution of inference problems. We conclude the manuscript by providing a few ideas for the development of tailored multi-scale inference methods.Comment: This manuscript will appear in the Journal of Coupled Systems and Multiscale Dynamics (American Scientific Publishers

Personalized Video Recommendation Using Rich Contents from Videos

Video recommendation has become an essential way of helping people explore the massive videos and discover the ones that may be of interest to them. In the existing video recommender systems, the models make the recommendations based on the user-video interactions and single specific content features. When the specific content features are unavailable, the performance of the existing models will seriously deteriorate. Inspired by the fact that rich contents (e.g., text, audio, motion, and so on) exist in videos, in this paper, we explore how to use these rich contents to overcome the limitations caused by the unavailability of the specific ones. Specifically, we propose a novel general framework that incorporates arbitrary single content feature with user-video interactions, named as collaborative embedding regression (CER) model, to make effective video recommendation in both in-matrix and out-of-matrix scenarios. Our extensive experiments on two real-world large-scale datasets show that CER beats the existing recommender models with any single content feature and is more time efficient. In addition, we propose a priority-based late fusion (PRI) method to gain the benefit brought by the integrating the multiple content features. The corresponding experiment shows that PRI brings real performance improvement to the baseline and outperforms the existing fusion methods

On social networks and collaborative recommendation

Social network systems, like last.fm, play a significant role in Web 2.0, containing large amounts of multimedia-enriched data that are enhanced both by explicit user-provided annotations and implicit aggregated feedback describing the personal preferences of each user. It is also a common tendency for these systems to encourage the creation of virtual networks among their users by allowing them to establish bonds of friendship and thus provide a novel and direct medium for the exchange of data. We investigate the role of these additional relationships in developing a track recommendation system. Taking into account both the social annotation and friendships inherent in the social graph established among users, items and tags, we created a collaborative recommendation system that effectively adapts to the personal information needs of each user. We adopt the generic framework of Random Walk with Restarts in order to provide with a more natural and efficient way to represent social networks. In this work we collected a representative enough portion of the music social network last.fm, capturing explicitly expressed bonds of friendship of the user as well as social tags. We performed a series of comparison experiments between the Random Walk with Restarts model and a user-based collaborative filtering method using the Pearson Correlation similarity. The results show that the graph model system benefits from the additional information embedded in social knowledge. In addition, the graph model outperforms the standard collaborative filtering method.</p

From Personalization to Adaptivity: Creating Immersive Visits through Interactive Digital Storytelling at the Acropolis Museum

Storytelling has recently become a popular way to guide museum visitors, replacing traditional exhibit-centric descriptions by story-centric cohesive narrations with references to the exhibits and multimedia content. This work presents the fundamental elements of the CHESS project approach, the goal of which is to provide adaptive, personalized, interactive storytelling for museum visits. We shortly present the CHESS project and its background, we detail the proposed storytelling and user models, we describe the provided functionality and we outline the main tools and mechanisms employed. Finally, we present the preliminary results of a recent evaluation study that are informing several directions for future work

Global sensitivity analysis for the boundary control of an open channel

The goal of this paper is to solve the global sensitivity analysis for a particular control problem. More precisely, the boundary control problem of an open-water channel is considered, where the boundary conditions are defined by the position of a down stream overflow gate and an upper stream underflow gate. The dynamics of the water depth and of the water velocity are described by the Shallow Water equations, taking into account the bottom and friction slopes. Since some physical parameters are unknown, a stabilizing boundary control is first computed for their nominal values, and then a sensitivity anal-ysis is performed to measure the impact of the uncertainty in the parameters on a given to-be-controlled output. The unknown physical parameters are de-scribed by some probability distribution functions. Numerical simulations are performed to measure the first-order and total sensitivity indices