17,439 research outputs found
A Survey on Software Testing Techniques using Genetic Algorithm
The overall aim of the software industry is to ensure delivery of high
quality software to the end user. To ensure high quality software, it is
required to test software. Testing ensures that software meets user
specifications and requirements. However, the field of software testing has a
number of underlying issues like effective generation of test cases,
prioritisation of test cases etc which need to be tackled. These issues demand
on effort, time and cost of the testing. Different techniques and methodologies
have been proposed for taking care of these issues. Use of evolutionary
algorithms for automatic test generation has been an area of interest for many
researchers. Genetic Algorithm (GA) is one such form of evolutionary
algorithms. In this research paper, we present a survey of GA approach for
addressing the various issues encountered during software testing.Comment: 13 Page
Recent Advances in Graph Partitioning
We survey recent trends in practical algorithms for balanced graph
partitioning together with applications and future research directions
Composing Distributed Data-intensive Web Services Using a Flexible Memetic Algorithm
Web Service Composition (WSC) is a particularly promising application of Web
services, where multiple individual services with specific functionalities are
composed to accomplish a more complex task, which must fulfil functional
requirements and optimise Quality of Service (QoS) attributes, simultaneously.
Additionally, large quantities of data, produced by technological advances,
need to be exchanged between services. Data-intensive Web services, which
manipulate and deal with those data, are of great interest to implement
data-intensive processes, such as distributed Data-intensive Web Service
Composition (DWSC). Researchers have proposed Evolutionary Computing (EC)
fully-automated WSC techniques that meet all the above factors. Some of these
works employed Memetic Algorithms (MAs) to enhance the performance of EC
through increasing its exploitation ability of in searching neighbourhood area
of a solution. However, those works are not efficient or effective. This paper
proposes an MA-based approach to solving the problem of distributed DWSC in an
effective and efficient manner. In particular, we develop an MA that hybridises
EC with a flexible local search technique incorporating distance of services.
An evaluation using benchmark datasets is carried out, comparing existing
state-of-the-art methods. Results show that our proposed method has the highest
quality and an acceptable execution time overall.Comment: arXiv admin note: text overlap with arXiv:1901.0556
Global Network Alignment
Motivation: High-throughput methods for detecting molecular interactions have lead to a plethora of biological network data with much more yet to come, stimulating the development of techniques for biological network alignment. Analogous to sequence alignment, efficient and reliable network alignment methods will improve our understanding of biological systems. Network alignment is computationally hard. Hence, devising efficient network alignment heuristics is currently one of the foremost challenges in computational biology. 

Results: We present a superior heuristic network alignment algorithm, called Matching-based GRAph ALigner (M-GRAAL), which can process and integrate any number and type of similarity measures between network nodes (e.g., proteins), including, but not limited to, any topological network similarity measure, sequence similarity, functional similarity, and structural similarity. This is efficient in resolving ties in similarity measures and in finding a combination of similarity measures yielding the largest biologically sound alignments. When used to align protein-protein interaction (PPI) networks of various species, M-GRAAL exposes the largest known functional and contiguous regions of network similarity. Hence, we use M-GRAAL’s alignments to predict functions of un-annotated proteins in yeast, human, and bacteria _C. jejuni_ and _E. coli_. Furthermore, using M-GRAAL to compare PPI networks of different herpes viruses, we reconstruct their phylogenetic relationship and our phylogenetic tree is the same as sequenced-based one
Combining Static and Dynamic Analysis for Vulnerability Detection
In this paper, we present a hybrid approach for buffer overflow detection in
C code. The approach makes use of static and dynamic analysis of the
application under investigation. The static part consists in calculating taint
dependency sequences (TDS) between user controlled inputs and vulnerable
statements. This process is akin to program slice of interest to calculate
tainted data- and control-flow path which exhibits the dependence between
tainted program inputs and vulnerable statements in the code. The dynamic part
consists of executing the program along TDSs to trigger the vulnerability by
generating suitable inputs. We use genetic algorithm to generate inputs. We
propose a fitness function that approximates the program behavior (control
flow) based on the frequencies of the statements along TDSs. This runtime
aspect makes the approach faster and accurate. We provide experimental results
on the Verisec benchmark to validate our approach.Comment: There are 15 pages with 1 figur
Frequent Pattern Finding in Integrated Biological Networks
Biomedical research is undergoing a revolution with the advance of high-throughput technologies. A major challenge in the post-genomic era is to understand how genes, proteins and small molecules are organized into signaling pathways and regulatory networks. To simplify the analysis of large complex molecular networks, strategies are sought to break them down into small yet relatively independent network modules, e.g. pathways and protein complexes.
In fulfillment of the motivation to find evolutionary origins of network modules, a novel strategy has been developed to uncover duplicated pathways and protein complexes. This search was first formulated into a computational problem which finds frequent patterns in integrated graphs. The whole framework was then successfully implemented as the software package BLUNT, which includes a parallelized version.
To evaluate the biological significance of the work, several large datasets were chosen, with each dataset targeting a different biological question. An application of BLUNT was performed on the yeast protein-protein interaction network, which is described. A large number of frequent patterns were discovered and predicted to be duplicated pathways. To explore how these pathways may have diverged since duplication, the differential regulation of duplicated pathways was studied at the transcriptional level, both in terms of time and location.
As demonstrated, this algorithm can be used as new data mining tool for large scale biological data in general. It also provides a novel strategy to study the evolution of pathways and protein complexes in a systematic way. Understanding how pathways and protein complexes evolve will greatly benefit the fundamentals of biomedical research
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