A graph-based approach for the retrieval of multi-modality medical images

Medical imaging has revolutionised modern medicine and is now an integral aspect of diagnosis and patient monitoring. The development of new imaging devices for a wide variety of clinical cases has spurred an increase in the data volume acquired in hospitals. These large data collections offer opportunities for search-based applications in evidence-based diagnosis, education, and biomedical research. However, conventional search methods that operate upon manual annotations are not feasible for this data volume. Content-based image retrieval (CBIR) is an image search technique that uses automatically derived visual features as search criteria and has demonstrable clinical benefits. However, very few studies have investigated the CBIR of multi-modality medical images, which are making a monumental impact in healthcare, e.g., combined positron emission tomography and computed tomography (PET-CT) for cancer diagnosis. In this thesis, we propose a new graph-based method for the CBIR of multi-modality medical images. We derive a graph representation that emphasises the spatial relationships between modalities by structurally constraining the graph based on image features, e.g., spatial proximity of tumours and organs. We also introduce a graph similarity calculation algorithm that prioritises the relationships between tumours and related organs. To enable effective human interpretation of retrieved multi-modality images, we also present a user interface that displays graph abstractions alongside complex multi-modality images. Our results demonstrated that our method achieved a high precision when retrieving images on the basis of tumour location within organs. The evaluation of our proposed UI design by user surveys revealed that it improved the ability of users to interpret and understand the similarity between retrieved PET-CT images. The work in this thesis advances the state-of-the-art by enabling a novel approach for the retrieval of multi-modality medical images

A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Unsupervised Visual and Textual Information Fusion in Multimedia Retrieval - A Graph-based Point of View

Multimedia collections are more than ever growing in size and diversity. Effective multimedia retrieval systems are thus critical to access these datasets from the end-user perspective and in a scalable way. We are interested in repositories of image/text multimedia objects and we study multimodal information fusion techniques in the context of content based multimedia information retrieval. We focus on graph based methods which have proven to provide state-of-the-art performances. We particularly examine two of such methods : cross-media similarities and random walk based scores. From a theoretical viewpoint, we propose a unifying graph based framework which encompasses the two aforementioned approaches. Our proposal allows us to highlight the core features one should consider when using a graph based technique for the combination of visual and textual information. We compare cross-media and random walk based results using three different real-world datasets. From a practical standpoint, our extended empirical analysis allow us to provide insights and guidelines about the use of graph based methods for multimodal information fusion in content based multimedia information retrieval.Comment: An extended version of the paper: Visual and Textual Information Fusion in Multimedia Retrieval using Semantic Filtering and Graph based Methods, by J. Ah-Pine, G. Csurka and S. Clinchant, submitted to ACM Transactions on Information System

Making Laplacians commute

In this paper, we construct multimodal spectral geometry by finding a pair of closest commuting operators (CCO) to a given pair of Laplacians. The CCOs are jointly diagonalizable and hence have the same eigenbasis. Our construction naturally extends classical data analysis tools based on spectral geometry, such as diffusion maps and spectral clustering. We provide several synthetic and real examples of applications in dimensionality reduction, shape analysis, and clustering, demonstrating that our method better captures the inherent structure of multi-modal data