On the synergy between adaptive physical layer and multiple-access control for integrated voice and data services in a cellular wireless network

In this paper, we propose a novel design to exploit the synergy between the multiple-access control (MAC) layer and the physical layer of a cellular wireless system with integrated voice and data services. As in a traditional design, the physical layer (channel encoder and modulator) is responsible for providing error protection for transmitting the packets over the hostile radio channel, while the MAC layer is responsible for allocating the precious bandwidth to the contending users for voice or data connections. However, a distinctive feature of our proposed design is that in the physical layer, a variable-rate adaptive channel encoder is employed to dynamically adjust the amount of forward error correction according to the time-varying wireless channel state such that the MAC layer, which is a reservation-based time-division multiple-access protocol, is able to make informed decisions as to bandwidth allocation. Specifically, based on the channel state information provided by the physical layer, the MAC protocol gives higher priority to users with better channel states. This novel synergistic mechanism between the two protocol layers can utilize the system bandwidth more effectively. The multiple-access performance of the proposed scheme is compared with two baseline systems. The first baseline system consists of the same reservation-based MAC protocol but with a traditional fixed-rate physical layer. The second system consists of the same reservation-based MAC protocol and the same channel adaptive physical layer, but without interaction between the two layers. All three protocols have a request queue, which stores the previous requests that survive the contention but are not allocated information slots. Our extensive simulation results demonstrate that significant performance gains are achieved through the exploitation of the synergy between the two protocol layers.published_or_final_versio

The application of forward error correction techniques in wireless ATM

Bibliography: pages 116-121.The possibility of providing wireless access to an ATM network promises nomadic users a communication tool of unparalleled power and flexibility. Unfortunately, the physical realization of a wireless A TM system is fraught with technical difficulties, not the least of which is the problem of supporting a traditional ATM protocol over a non-benign wireless link. The objective of this thesis, titled "The Application of Forward Error Correction Techniques in Wireless ATM' is to examine the feasibility of using forward error correction techniques to improve the perceived channel characteristics to the extent that the channel becomes transparent to the higher layers and allows the use of an unmodified A TM protocol over the channel. In the course of the investigation that this dissertation describes, three possible error control strategies were suggested for implementation in a generic wireless channel. These schemes used a combination of forward error correction coding schemes, automatic repeat request schemes and interleavers to combat the impact of bit errors on the performance of the link. The following error control strategies were considered : 1. A stand alone fixed rate Reed-Solomon encoder/decoder with automatic repeat request. 2. A concatenated Reed-Solomon, convolution encoder/decoder with automatic request and convolution interleaving for the convolution codec. 3. A dynamic rate encoder/decoder using either a concatenated Reed-Solomon, convolution scheme or a Reed-Solomon only scheme with variable length Reed-Solomon words

Mobile Ad-Hoc Networks

Being infrastructure-less and without central administration control, wireless ad-hoc networking is playing a more and more important role in extending the coverage of traditional wireless infrastructure (cellular networks, wireless LAN, etc). This book includes state-of the-art techniques and solutions for wireless ad-hoc networks. It focuses on the following topics in ad-hoc networks: vehicular ad-hoc networks, security and caching, TCP in ad-hoc networks and emerging applications. It is targeted to provide network engineers and researchers with design guidelines for large scale wireless ad hoc networks

Pacific Symposium on Biocomputing 2023

The Pacific Symposium on Biocomputing (PSB) 2023 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2023 will be held on January 3-7, 2023 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2023 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field

Dichotomic role of NAADP/two-pore channel 2/Ca2+ signaling in regulating neural differentiation of mouse embryonic stem cells

Poster Presentation - Stem Cells and Pluripotency: abstract no. 1866The mobilization of intracellular Ca2+stores is involved in diverse cellular functions, including cell proliferation and differentiation. At least three endogenous Ca2+mobilizing messengers have been identified, including inositol trisphosphate (IP3), cyclic adenosine diphosphoribose (cADPR), and nicotinic adenine acid dinucleotide phosphate (NAADP). Similar to IP3, NAADP can mobilize calcium release in a wide variety of cell types and species, from plants to animals. Moreover, it has been previously shown that NAADP but not IP3-mediated Ca2+increases can potently induce neuronal differentiation in PC12 cells. Recently, two pore channels (TPCs) have been identified as a novel family of NAADP-gated calcium release channels in endolysosome. Therefore, it is of great interest to examine the role of TPC2 in the neural differentiation of mouse ES cells. We found that the expression of TPC2 is markedly decreased during the initial ES cell entry into neural progenitors, and the levels of TPC2 gradually rebound during the late stages of neurogenesis. Correspondingly, perturbing the NAADP signaling by TPC2 knockdown accelerates mouse ES cell differentiation into neural progenitors but inhibits these neural progenitors from committing to the final neural lineage. Interestingly, TPC2 knockdown has no effect on the differentiation of astrocytes and oligodendrocytes of mouse ES cells. Overexpression of TPC2, on the other hand, inhibits mouse ES cell from entering the neural lineage. Taken together, our data indicate that the NAADP/TPC2-mediated Ca2+signaling pathway plays a temporal and dichotomic role in modulating the neural lineage entry of ES cells; in that NAADP signaling antagonizes ES cell entry to early neural progenitors, but promotes late neural differentiation.postprin