1,220 research outputs found

    Emerging Linguistic Functions in Early Infancy

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    This paper presents results from experimental studies on early language acquisition in infants and attempts to interpret the experimental results within the framework of the Ecological Theory of Language Acquisition (ETLA) recently proposed by (Lacerda et al., 2004a). From this perspective, the infant’s first steps in the acquisition of the ambient language are seen as a consequence of the infant’s general capacity to represent sensory input and the infant’s interaction with other actors in its immediate ecological environment. On the basis of available experimental evidence, it will be argued that ETLA offers a productive alternative to traditional descriptive views of the language acquisition process by presenting an operative model of how early linguistic function may emerge through interaction

    Wafer-scale process and materials optimization in cross-flow atomic layer deposition

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    The exceptional thickness control (atomic scale) and conformality (uniformity over nanoscale 3D features) of atomic layer deposition (ALD) has made it the process of choice for numerous applications from microelectronics to nanotechnology, and for a wide variety of ALD processes and resulting materials. While its benefits derive from self-terminated chemisorbed reactions of alternatively supplied gas precursors, identifying a suitable process window in which ALD's benefits are realized can be a challenge, even in favorable cases. In this work, a strategy exploiting in-situ gas phase sensing in conjunction with ex-situ measurements of the film properties at the wafer scale is employed to explore and optimize the prototypical Al2O3 ALD process. Downstream mass-spectrometry is first used to rapidly identify across the [H2O x Al(CH3)3] process space the exposure conditions leading to surface saturation. The impact of precursor doses outside as well as inside the parameter space outlined by mass-spectrometry is then investigated by characterizing film properties across 100 mm wafer using spectroscopic ellipsometry, CV and IV electrical characterization, XPS and SIMS. Under ideal dose conditions, excellent thickness uniformity was achieved (1sigma/mean<1%) in conjunction with a deposition rate and electrical properties in good agreement with best literature data. As expected, under-dosing of precursor results in depletion of film growth in the flow direction across the wafer surface. Since adsorbed species are reactive with respect to subsequent dose of the complementary precursor, such depletion magnifies non-uniformities as seen in the cross-flow reactor, thereby decorating deviations from a suitable ALD process recipe. Degradation of the permittivity and leakage current density across the wafer was observed though the film composition remained unchanged. Upon higher water dose in the over-exposure regime, deposition rates increased by up to 40% while the uniformity degraded. In contrast, overdosing of TMA and ozone (used for comparison to water) did not affect the process performances. These results point to complex saturation dynamics of water dependent on partial pressure and potential multilayer adsorption caused by hydrogen-bonding

    Physical dependencies in accident sequence analysis

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    Includes bibliographical references (leaves 25-26)Supported by the Office of Nuclear Regulatory Research, United States Nuclear Regulatory Commission. NRC-04-88-14

    JOINING SEQUENCE ANALYSIS AND OPTIMIZATION FOR IMPROVED GEOMETRICAL QUALITY

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    Disturbances in the manufacturing and assembly processes cause geometrical variation from the ideal geometry. This variation eventually results in functional and aesthetic problems in the final product. Being able to control the disturbances is the desire of the manufacturing industry. \ua0 Joining sequences impact the final geometrical outcome in an assembly considerably. To optimize the sequence for improved geometrical outcome is both experimentally and computationally expensive. In the simulation-based approaches, based on the finite element method, a large number of sequences need to be evaluated.\ua0 In this thesis, the simulation-based joining sequence optimization using non-rigid variation simulation is studied. Initially, the limitation of the applied algorithms in the literature has been addressed. A rule-based optimization approach based on meta-heuristic algorithms and heuristic search methods is introduced to increase the previously applied algorithms\u27 time-efficiency and accuracy. Based on the identified rules and heuristics, a reduced formulation of the sequence optimization is introduced by identifying the critical points for geometrical quality. A subset of the sequence problem is identified and solved in this formulation.\ua0 For real-time optimization of the joining sequence problem, time-efficiency needs to be further enhanced by parallel computations. By identifying the sequence-deformation behavior in the assemblies, black-box surrogate models are introduced, enabling parallel evaluations and accurate approximation of the geometrical quality. Based on this finding, a deterministic stepwise search algorithm for rapid identification of the optimal sequence is introduced.\ua0 Furthermore, a numerical approach to identify the number, location from a set of alternatives, and sequence of the critical joining points for geometrical quality is introduced. Finally, the cause of the various deformations achieved by joining sequences is identified. A time-efficient non-rigid variation simulation approach for evaluating the geometrical quality with respect to the sequences is proposed. \ua0 The results achieved from the studies presented indicate that the simulation-based real-time optimization of the joining sequences is achievable through a parallelized search algorithm and a rapid evaluation of the sequences. The critical joining points for geometrical quality are identified while the sequence is optimized. The results help control the assembly process with respect to the joining operation, improve the geometrical quality, and save significant computational time

    'Cutting' and 'breaking' events in Akan

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    This study investigates the grammar and semantics of verbs that describe separation events in Asante Twi (Akan), a Kwa (Niger-Congo) language spoken in Ghana. It adopts a constructionist approach combined with a 'monosemic bias' perspective in the analysis. It theoretical starting point is that contextual interpretations are derived from the interaction of the prototypical meanings of verbs and their arguments. A multi-method approach was used in data gathering: (i) compilation of verbs that code separation as well as sentences in which they are used from literary texts (bibles, and novels) and dictionaries. (ii) Descriptions of separation activities elicited using video-stimuli Bohnemeyer et al. (2001), 61 video clips depicting cutting and breaking events (fieldmanuals.mpi.nl) supplemented by 82 clips created by the author involving culturally appropriate objects (Agyepong 2015). (iii) Spontaneous narratives, and procedural discourses about cultural events/practices involving separation e.g. cooking, palm-wine tapping. (iv) Introspection based on the author's native speaker intuitions. The main findings of the thesis are that there are two central verbs in the separation domain in Akan: twá 'to cut' and bú 'to break'. There are, in addition, more specialized verbs for specific types of object separation, e.g. nú 'harvest palm fruit by poking with a bladed instrument' or pòrò 'to pluck fruit'. The choice of a particular verb in context is determined by the following parameters: instrument involvement, manner of separation, physical properties of entities as well as the end-state result of the situation. Crucially, the thesis further addresses the challenge of how to account for the interpretation of the typical as well as atypical argument realization patterns associated with the separation verbs. It shows how constructional meanings contribute to the interpretation of collocations of the verbs. Other principles such as coercion, addition and suppression of components in the lexical semantics of both the verbs and its arguments as well as cultural implicatures are invoked in the compositional process of calculating the contextual interpretations

    Cell-Instructive Surface Gradients of Photoresponsive Amyloid-like Fibrils

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    [Image: see text] Gradients of bioactive molecules play a crucial role in various biological processes like vascularization, tissue regeneration, or cell migration. To study these complex biological systems, it is necessary to control the concentration of bioactive molecules on their substrates. Here, we created a photochemical strategy to generate gradients using amyloid-like fibrils as scaffolds functionalized with a model epitope, that is, the integrin-binding peptide RGD, to modulate cell adhesion. The self-assembling β-sheet forming peptide (CKFKFQF) was connected to the RGD epitope via a photosensitive nitrobenzyl linker and assembled into photoresponsive nanofibrils. The fibrils were spray-coated on glass substrates and macroscopic gradients were generated by UV-light over a centimeter-scale. We confirmed the gradient formation using matrix-assisted laser desorption ionization mass spectroscopy imaging (MALDI-MSI), which directly visualizes the molecular species on the surface. The RGD gradient was used to instruct cells. In consequence, A549 adapted their adhesion properties in dependence of the RGD-epitope density
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