188,565 research outputs found

    Robust Machine Learning-Based Correction on Automatic Segmentation of the Cerebellum and Brainstem.

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    Automated segmentation is a useful method for studying large brain structures such as the cerebellum and brainstem. However, automated segmentation may lead to inaccuracy and/or undesirable boundary. The goal of the present study was to investigate whether SegAdapter, a machine learning-based method, is useful for automatically correcting large segmentation errors and disagreement in anatomical definition. We further assessed the robustness of the method in handling size of training set, differences in head coil usage, and amount of brain atrophy. High resolution T1-weighted images were acquired from 30 healthy controls scanned with either an 8-channel or 32-channel head coil. Ten patients, who suffered from brain atrophy because of fragile X-associated tremor/ataxia syndrome, were scanned using the 32-channel head coil. The initial segmentations of the cerebellum and brainstem were generated automatically using Freesurfer. Subsequently, Freesurfer's segmentations were both manually corrected to serve as the gold standard and automatically corrected by SegAdapter. Using only 5 scans in the training set, spatial overlap with manual segmentation in Dice coefficient improved significantly from 0.956 (for Freesurfer segmentation) to 0.978 (for SegAdapter-corrected segmentation) for the cerebellum and from 0.821 to 0.954 for the brainstem. Reducing the training set size to 2 scans only decreased the Dice coefficient ≤0.002 for the cerebellum and ≤ 0.005 for the brainstem compared to the use of training set size of 5 scans in corrective learning. The method was also robust in handling differences between the training set and the test set in head coil usage and the amount of brain atrophy, which reduced spatial overlap only by <0.01. These results suggest that the combination of automated segmentation and corrective learning provides a valuable method for accurate and efficient segmentation of the cerebellum and brainstem, particularly in large-scale neuroimaging studies, and potentially for segmenting other neural regions as well

    Topology, homogeneity and scale factors for object detection: application of eCognition software for urban mapping using multispectral satellite image

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    The research scope of this paper is to apply spatial object based image analysis (OBIA) method for processing panchromatic multispectral image covering study area of Brussels for urban mapping. The aim is to map different land cover types and more specifically, built-up areas from the very high resolution (VHR) satellite image using OBIA approach. A case study covers urban landscapes in the eastern areas of the city of Brussels, Belgium. Technically, this research was performed in eCognition raster processing software demonstrating excellent results of image segmentation and classification. The tools embedded in eCognition enabled to perform image segmentation and objects classification processes in a semi-automated regime, which is useful for the city planning, spatial analysis and urban growth analysis. The combination of the OBIA method together with technical tools of the eCognition demonstrated applicability of this method for urban mapping in densely populated areas, e.g. in megapolis and capital cities. The methodology included multiresolution segmentation and classification of the created objects.Comment: 6 pages, 12 figures, INSO2015, Ed. by A. Girgvliani et al. Akaki Tsereteli State University, Kutaisi (Imereti), Georgi

    Automatic Renal Segmentation in DCE-MRI using Convolutional Neural Networks

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    Kidney function evaluation using dynamic contrast-enhanced MRI (DCE-MRI) images could help in diagnosis and treatment of kidney diseases of children. Automatic segmentation of renal parenchyma is an important step in this process. In this paper, we propose a time and memory efficient fully automated segmentation method which achieves high segmentation accuracy with running time in the order of seconds in both normal kidneys and kidneys with hydronephrosis. The proposed method is based on a cascaded application of two 3D convolutional neural networks that employs spatial and temporal information at the same time in order to learn the tasks of localization and segmentation of kidneys, respectively. Segmentation performance is evaluated on both normal and abnormal kidneys with varying levels of hydronephrosis. We achieved a mean dice coefficient of 91.4 and 83.6 for normal and abnormal kidneys of pediatric patients, respectively
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