51 research outputs found

    직접 볼륨 렌더링의 전이 함수 설계에 관한 연구

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    학위논문 (박사)-- 서울대학교 대학원 : 전기·컴퓨터공학부, 2017. 2. 신영길.Although direct volume rendering (DVR) has become a commodity, the design of transfer functions still a challenge. Transfer functions which map data values to optical properties (i.e., colors and opacities) highlight features of interests as well as hide unimportant regions, dramatically impacting on the quality of the visualization. Therefore, for the effective rendering of interesting features, the design of transfer functions is very important and challenging task. Furthermore, manipulation of these transfer functions is tedious and time-consuming task. In this paper, we propose a 3D spatial field for accurately identifying and visually distinguishing interesting features as well as a mechanism for data exploration using multi-dimensional transfer function. First, we introduce a 3D spatial field for the effective visualization of constricted tubular structures, called as a stenosis map which stores the degree of constriction at each voxel. Constrictions within tubular structures are quantified by using newly proposed measures (i.e., line similarity measure and constriction measure) based on the localized structure analysis, and classified with a proposed transfer function mapping the degree of constriction to color and opacity. We show the application results of our method to the visualization of coronary artery stenoses. We present performance evaluations using twenty-eight clinical datasets, demonstrating high accuracy and efficacy of our proposed method. Second, we propose a new multi-dimensional transfer function which incorporates texture features calculated from statistically homogeneous regions. This approach employs parallel coordinates to provide an intuitive interface for exploring a new multi-dimensional transfer function space. Three specific ways to use a new transfer function based on parallel coordinates enables the effective exploration of large and complex datasets. We present a mechanism for data exploration with a new transfer function space, demonstrating the practical efficacy of our proposed method. Through a study on transfer function design for DVR, we propose two useful approaches. First method to saliently visualize the constrictions within tubular structures and interactively adjust the visual appearance of the constrictions delivers a substantial aid in radiologic practice. Furthermore, second method to classify objects with our intuitive interface utilizing parallel coordinates proves to be a powerful tool for complex data exploration.Chapter 1 Introduction 1 1.1 Background 1 1.1.1 Volume rendering 1 1.1.2 Computer-aided diagnosis 3 1.1.3 Parallel coordinates 5 1.2 Problem statement 8 1.3 Main contribution 12 1.4 Organization of dissertation 16 Chapter 2 Related Work 17 2.1 Transfer function 17 2.1.1 Transfer functions based on spatial characteristics 17 2.1.2 Opacity modulation techniques 20 2.1.3 Multi-dimensional transfer functions 22 2.1.4 Manipulation mechanism for transfer functions 25 2.2 Coronary artery stenosis 28 2.3 Parallel coordinates 32 Chapter 3 Volume Visualization of Constricted Tubular Structures 36 3.1 Overview 36 3.2 Localized structure analysis 37 3.3 Stenosis map 39 3.3.1 Overview 39 3.3.2 Detection of tubular structures 40 3.3.3 Stenosis map computation 49 3.4 Stenosis-based classification 52 3.4.1 Overview 52 3.4.2 Constriction-encoded volume rendering 52 3.4.3 Opacity modulation based on constriction 54 3.5 GPU implementation 57 3.6 Experimental results 59 3.6.1 Clinical data preparation 59 3.6.2 Qualitative evaluation 60 3.6.3 Quantitative evaluation 63 3.6.4 Comparison with previous methods 66 3.6.5 Parameter study 69 Chapter 4 Interactive Multi-Dimensional Transfer Function Using Adaptive Block Based Feature Analysis 73 4.1 Overview 73 4.2 Extraction of statistical features 74 4.3 Extraction of texture features 78 4.4 Multi-dimensional transfer function design using parallel coordinates 81 4.5 Experimental results 86 Chapter 5 Conclusion 90 Bibliography 92 초 록 107Docto

    Diseases of the Brain, Head and Neck, Spine 2020–2023

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    This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care

    Preclinical MRI of the Kidney

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    This Open Access volume provides readers with an open access protocol collection and wide-ranging recommendations for preclinical renal MRI used in translational research. The chapters in this book are interdisciplinary in nature and bridge the gaps between physics, physiology, and medicine. They are designed to enhance training in renal MRI sciences and improve the reproducibility of renal imaging research. Chapters provide guidance for exploring, using and developing small animal renal MRI in your laboratory as a unique tool for advanced in vivo phenotyping, diagnostic imaging, and research into potential new therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Preclinical MRI of the Kidney: Methods and Protocols is a valuable resource and will be of importance to anyone interested in the preclinical aspect of renal and cardiorenal diseases in the fields of physiology, nephrology, radiology, and cardiology. This publication is based upon work from COST Action PARENCHIMA, supported by European Cooperation in Science and Technology (COST). COST (www.cost.eu) is a funding agency for research and innovation networks. COST Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. PARENCHIMA (renalmri.org) is a community-driven Action in the COST program of the European Union, which unites more than 200 experts in renal MRI from 30 countries with the aim to improve the reproducibility and standardization of renal MRI biomarkers

    Thrust Area Report, Engineering Research, Development and Technology

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    Preclinical MRI of the kidney : methods and protocols

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    This Open Access volume provides readers with an open access protocol collection and wide-ranging recommendations for preclinical renal MRI used in translational research. The chapters in this book are interdisciplinary in nature and bridge the gaps between physics, physiology, and medicine. They are designed to enhance training in renal MRI sciences and improve the reproducibility of renal imaging research. Chapters provide guidance for exploring, using and developing small animal renal MRI in your laboratory as a unique tool for advanced in vivo phenotyping, diagnostic imaging, and research into potential new therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Preclinical MRI of the Kidney: Methods and Protocols is a valuable resource and will be of importance to anyone interested in the preclinical aspect of renal and cardiorenal diseases in the fields of physiology, nephrology, radiology, and cardiology. This publication is based upon work from COST Action PARENCHIMA, supported by European Cooperation in Science and Technology (COST). COST (www.cost.eu) is a funding agency for research and innovation networks. COST Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. PARENCHIMA (renalmri.org) is a community-driven Action in the COST program of the European Union, which unites more than 200 experts in renal MRI from 30 countries with the aim to improve the reproducibility and standardization of renal MRI biomarkers

    Microscopy and Analysis

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    Microscopes represent tools of the utmost importance for a wide range of disciplines. Without them, it would have been impossible to stand where we stand today in terms of understanding the structure and functions of organelles and cells, tissue composition and metabolism, or the causes behind various pathologies and their progression. Our knowledge on basic and advanced materials is also intimately intertwined to the realm of microscopy, and progress in key fields of micro- and nanotechnologies critically depends on high-resolution imaging systems. This volume includes a series of chapters that address highly significant scientific subjects from diverse areas of microscopy and analysis. Authoritative voices in their fields present in this volume their work or review recent trends, concepts, and applications, in a manner that is accessible to a broad readership audience from both within and outside their specialist area
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