78,321 research outputs found
Considerations for a design and operations knowledge support system for Space Station Freedom
Engineering and operations of modern engineered systems depend critically upon detailed design and operations knowledge that is accurate and authoritative. A design and operations knowledge support system (DOKSS) is a modern computer-based information system providing knowledge about the creation, evolution, and growth of an engineered system. The purpose of a DOKSS is to provide convenient and effective access to this multifaceted information. The complexity of Space Station Freedom's (SSF's) systems, elements, interfaces, and organizations makes convenient access to design knowledge especially important, when compared to simpler systems. The life cycle length, being 30 or more years, adds a new dimension to space operations, maintenance, and evolution. Provided here is a review and discussion of design knowledge support systems to be delivered and operated as a critical part of the engineered system. A concept of a DOKSS for Space Station Freedom (SSF) is presented. This is followed by a detailed discussion of a DOKSS for the Lyndon B. Johnson Space Center and Work Package-2 portions of SSF
Retrosynthetic reaction prediction using neural sequence-to-sequence models
We describe a fully data driven model that learns to perform a retrosynthetic
reaction prediction task, which is treated as a sequence-to-sequence mapping
problem. The end-to-end trained model has an encoder-decoder architecture that
consists of two recurrent neural networks, which has previously shown great
success in solving other sequence-to-sequence prediction tasks such as machine
translation. The model is trained on 50,000 experimental reaction examples from
the United States patent literature, which span 10 broad reaction types that
are commonly used by medicinal chemists. We find that our model performs
comparably with a rule-based expert system baseline model, and also overcomes
certain limitations associated with rule-based expert systems and with any
machine learning approach that contains a rule-based expert system component.
Our model provides an important first step towards solving the challenging
problem of computational retrosynthetic analysis
Instruction-Level Abstraction (ILA): A Uniform Specification for System-on-Chip (SoC) Verification
Modern Systems-on-Chip (SoC) designs are increasingly heterogeneous and
contain specialized semi-programmable accelerators in addition to programmable
processors. In contrast to the pre-accelerator era, when the ISA played an
important role in verification by enabling a clean separation of concerns
between software and hardware, verification of these "accelerator-rich" SoCs
presents new challenges. From the perspective of hardware designers, there is a
lack of a common framework for the formal functional specification of
accelerator behavior. From the perspective of software developers, there exists
no unified framework for reasoning about software/hardware interactions of
programs that interact with accelerators. This paper addresses these challenges
by providing a formal specification and high-level abstraction for accelerator
functional behavior. It formalizes the concept of an Instruction Level
Abstraction (ILA), developed informally in our previous work, and shows its
application in modeling and verification of accelerators. This formal ILA
extends the familiar notion of instructions to accelerators and provides a
uniform, modular, and hierarchical abstraction for modeling software-visible
behavior of both accelerators and programmable processors. We demonstrate the
applicability of the ILA through several case studies of accelerators (for
image processing, machine learning, and cryptography), and a general-purpose
processor (RISC-V). We show how the ILA model facilitates equivalence checking
between two ILAs, and between an ILA and its hardware finite-state machine
(FSM) implementation. Further, this equivalence checking supports accelerator
upgrades using the notion of ILA compatibility, similar to processor upgrades
using ISA compatibility.Comment: 24 pages, 3 figures, 3 table
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