Linking social media, medical literature, and clinical notes using deep learning.

Researchers analyze data, information, and knowledge through many sources, formats, and methods. The dominant data format includes text and images. In the healthcare industry, professionals generate a large quantity of unstructured data. The complexity of this data and the lack of computational power causes delays in analysis. However, with emerging deep learning algorithms and access to computational powers such as graphics processing unit (GPU) and tensor processing units (TPUs), processing text and images is becoming more accessible. Deep learning algorithms achieve remarkable results in natural language processing (NLP) and computer vision. In this study, we focus on NLP in the healthcare industry and collect data not only from electronic medical records (EMRs) but also medical literature and social media. We propose a framework for linking social media, medical literature, and EMRs clinical notes using deep learning algorithms. Connecting data sources requires defining a link between them, and our key is finding concepts in the medical text. The National Library of Medicine (NLM) introduces a Unified Medical Language System (UMLS) and we use this system as the foundation of our own system. We recognize social media’s dynamic nature and apply supervised and semi-supervised methodologies to generate concepts. Named entity recognition (NER) allows efficient extraction of information, or entities, from medical literature, and we extend the model to process the EMRs’ clinical notes via transfer learning. The results include an integrated, end-to-end, web-based system solution that unifies social media, literature, and clinical notes, and improves access to medical knowledge for the public and experts

Analyzing fluctuation of topics and public sentiment through social media data

Over the past decade years, Internet users were expending rapidly in the world. They form various online social networks through such Internet platforms as Twitter, Facebook and Instagram. These platforms provide a fast way that helps their users receive and disseminate information and express personal opinions in virtual space. When dealing with massive and chaotic social media data, how to accurately determine what events or concepts users are discussing is an interesting and important problem. This dissertation work mainly consists of two parts. First, this research pays attention to mining the hidden topics and user interest trend by analyzing real-world social media activities. Topic modeling and sentiment analysis methods are proposed to classify the social media posts into different sentiment classes and then discover the trend of sentiment based on different topics over time. The presented case study focuses on COVID-19 pandemic that started in 2019. A large amount of Twitter data is collected and used to discover the vaccine-related topics during the pre- and post-vaccine emergency use period. By using the proposed framework, 11 vaccine-related trend topics are discovered. Ultimately the discovered topics can be used to improve the readability of confusing messages about vaccines on social media and provide effective results to support policymakers in making their policy their informed decisions about public health. Second, using conventional topic models cannot deal with the sparsity problem of short text. A novel topic model, named Topic Noise based-Biterm Topic Model with FastText embeddings (TN-BTMF), is proposed to deal with this problem. Word co-occurrence patterns (i.e. biterms) are dirctly generated in BTM. A scoring method based on word co-occurrence and semantic similarity is proposed to detect noise biterms. In th

An IoT based Virtual Coaching System (VSC) for Assisting Activities of Daily Life

Nowadays aging of the population is becoming one of the main concerns of theworld. It is estimated that the number of people aged over 65 will increase from 461million to 2 billion in 2050. This substantial increment in the elderly population willhave significant consequences in the social and health care system. Therefore, in thecontext of Ambient Intelligence (AmI), the Ambient Assisted Living (AAL) has beenemerging as a new research area to address problems related to the aging of the population. AAL technologies based on embedded devices have demonstrated to be effectivein alleviating the social- and health-care issues related to the continuous growing of theaverage age of the population. Many smart applications, devices and systems have beendeveloped to monitor the health status of elderly, substitute them in the accomplishment of activities of the daily life (especially in presence of some impairment or disability),alert their caregivers in case of necessity and help them in recognizing risky situations.Such assistive technologies basically rely on the communication and interaction be-tween body sensors, smart environments and smart devices. However, in such contextless effort has been spent in designing smart solutions for empowering and supportingthe self-efficacy of people with neurodegenerative diseases and elderly in general. Thisthesis fills in the gap by presenting a low-cost, non intrusive, and ubiquitous VirtualCoaching System (VCS) to support people in the acquisition of new behaviors (e.g.,taking pills, drinking water, finding the right key, avoiding motor blocks) necessary tocope with needs derived from a change in their health status and a degradation of theircognitive capabilities as they age. VCS is based on the concept of extended mind intro-duced by Clark and Chalmers in 1998. They proposed the idea that objects within theenvironment function as a part of the mind. In my revisiting of the concept of extendedmind, the VCS is composed of a set of smart objects that exploit the Internet of Things(IoT) technology and machine learning-based algorithms, in order to identify the needsof the users and react accordingly. In particular, the system exploits smart tags to trans-form objects commonly used by people (e.g., pillbox, bottle of water, keys) into smartobjects, it monitors their usage according to their needs, and it incrementally guidesthem in the acquisition of new behaviors related to their needs. To implement VCS, thisthesis explores different research directions and challenges. First of all, it addresses thedefinition of a ubiquitous, non-invasive and low-cost indoor monitoring architecture byexploiting the IoT paradigm. Secondly, it deals with the necessity of developing solu-tions for implementing coaching actions and consequently monitoring human activitiesby analyzing the interaction between people and smart objects. Finally, it focuses on the design of low-cost localization systems for indoor environment, since knowing theposition of a person provides VCS with essential information to acquire information onperformed activities and to prevent risky situations. In the end, the outcomes of theseresearch directions have been integrated into a healthcare application scenario to imple-ment a wearable system that prevents freezing of gait in people affected by Parkinson\u2019sDisease

Mining Social Media to Understand Consumers' Health Concerns and the Public's Opinion on Controversial Health Topics.

Social media websites are increasingly used by the general public as a venue to express health concerns and discuss controversial medical and public health issues. This information could be utilized for the purposes of public health surveillance as well as solicitation of public opinions. In this thesis, I developed methods to extract health-related information from multiple sources of social media data, and conducted studies to generate insights from the extracted information using text-mining techniques. To understand the availability and characteristics of health-related information in social media, I first identified the users who seek health information online and participate in online health community, and analyzed their motivations and behavior by two case studies of user-created groups on MedHelp and a diabetes online community on Twitter. Through a review of tweets mentioning eye-related medical concepts identified by MetaMap, I diagnosed the common reasons of tweets mislabeled by natural language processing tools tuned for biomedical texts, and trained a classifier to exclude non medically-relevant tweets to increase the precision of the extracted data. Furthermore, I conducted two studies to evaluate the effectiveness of understanding public opinions on controversial medical and public health issues from social media information using text-mining techniques. The first study applied topic modeling and text summarization to automatically distill users' key concerns about the purported link between autism and vaccines. The outputs of two methods cover most of the public concerns of MMR vaccines reported in previous survey studies. In the second study, I estimated the public's view on the ac{ACA} by applying sentiment analysis to four years of Twitter data, and demonstrated that the the rates of positive/negative responses measured by tweet sentiment are in general agreement with the results of Kaiser Family Foundation Poll. Finally, I designed and implemented a system which can automatically collect and analyze online news comments to help researchers, public health workers, and policy makers to better monitor and understand the public's opinion on issues such as controversial health-related topics.PhDInformationUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/120714/1/owenliu_1.pd

Understanding Bots on Social Media - An Application in Disaster Response

abstract: Social media has become a primary platform for real-time information sharing among users. News on social media spreads faster than traditional outlets and millions of users turn to this platform to receive the latest updates on major events especially disasters. Social media bridges the gap between the people who are affected by disasters, volunteers who offer contributions, and first responders. On the other hand, social media is a fertile ground for malicious users who purposefully disturb the relief processes facilitated on social media. These malicious users take advantage of social bots to overrun social media posts with fake images, rumors, and false information. This process causes distress and prevents actionable information from reaching the affected people. Social bots are automated accounts that are controlled by a malicious user and these bots have become prevalent on social media in recent years. In spite of existing efforts towards understanding and removing bots on social media, there are at least two drawbacks associated with the current bot detection algorithms: general-purpose bot detection methods are designed to be conservative and not label a user as a bot unless the algorithm is highly confident and they overlook the effect of users who are manipulated by bots and (unintentionally) spread their content. This study is trifold. First, I design a Machine Learning model that uses content and context of social media posts to detect actionable ones among them; it specifically focuses on tweets in which people ask for help after major disasters. Second, I focus on bots who can be a facilitator of malicious content spreading during disasters. I propose two methods for detecting bots on social media with a focus on the recall of the detection. Third, I study the characteristics of users who spread the content of malicious actors. These features have the potential to improve methods that detect malicious content such as fake news.Dissertation/ThesisDoctoral Dissertation Computer Science 201

情報検索における意味的ギャップの解消 : トピックモデルを用いた先進的画像探索

Tohoku University徳山豪課

Intelligent Biosignal Processing in Wearable and Implantable Sensors

This reprint provides a collection of papers illustrating the state-of-the-art of smart processing of data coming from wearable, implantable or portable sensors. Each paper presents the design, databases used, methodological background, obtained results, and their interpretation for biomedical applications. Revealing examples are brain–machine interfaces for medical rehabilitation, the evaluation of sympathetic nerve activity, a novel automated diagnostic tool based on ECG data to diagnose COVID-19, machine learning-based hypertension risk assessment by means of photoplethysmography and electrocardiography signals, Parkinsonian gait assessment using machine learning tools, thorough analysis of compressive sensing of ECG signals, development of a nanotechnology application for decoding vagus-nerve activity, detection of liver dysfunction using a wearable electronic nose system, prosthetic hand control using surface electromyography, epileptic seizure detection using a CNN, and premature ventricular contraction detection using deep metric learning. Thus, this reprint presents significant clinical applications as well as valuable new research issues, providing current illustrations of this new field of research by addressing the promises, challenges, and hurdles associated with the synergy of biosignal processing and AI through 16 different pertinent studies. Covering a wide range of research and application areas, this book is an excellent resource for researchers, physicians, academics, and PhD or master students working on (bio)signal and image processing, AI, biomaterials, biomechanics, and biotechnology with applications in medicine