WEARABLE MULTI-SENSOR SYSTEM FOR TELEMEDICINE APPLICATIONS

In this paper, we describe a technical design of wearable multi-sensor systems for physiological data measurement and wide medical applications, significantly impacted in telehealth. The monitors are composed of three analog front-end (AFE) devices, which assist with interfacing digital electronics to the noise-, time-sensitive physiological sensors for measuring ECG (heart-rate monitor), RR (respiration-rate monitor), SRL (skin resistivity monitor). These three types of sensors can be used separately or together and allow to determine a number of parameters for the assessment of mental and physical condition. The system is designed based on requirements for demanding environments even outside the realm of medical applications, and in accordance with Health and Safety at Work directives (89/391/CE and Seveso-II 96/82/EC) for occupational hygiene, medical, rehabilitation, sports and fitness applications

Cancelling Harmonic Power Line Interference in Biopotentials

Biopotential signals, like the electrocardiogram (ECG), electroencephalogram (EEG), electromyogram (EMG), and so on, contain vital information about the health state of human body. The morphology and time/frequency parameters of the biopotentials are of interest when diagnostic information is extracted and analyzed. The powerline interference (PLI), with the fundamental PLI component of 50 Hz/60 Hz and its harmonics, is one of the most disturbing noise sources in biopotential recordings that hampers the analysis of the electrical signals generated by the human body. The aim of this chapter is to review the existing methods to eliminate harmonics PLI from biopotential signals and to analyze the distortion introduced by some of the most basic approaches for PLI cancelation and whether this distortion affects the diagnostic performance in biopotentials investigations

A real-time wearable emotion detection headband based on EEG measurement

A real-time emotion detection system based on electroencephalogram (EEG) measurement has been realised by means of an emotion detection headband coupled with printed signal acquisition electrodes and open source signal processing software (OpenViBE). Positive and negative emotions are the states classified and the Theta, Alpha, Beta and Gamma frequency bands are selected for the signal processing. It is found that, by using a combination of Power Spectral Density (PSD), Signal Power (SP) and Common Spatial Pattern (CSP) as the features, the highest subject-dependent accuracy (86.83%) and independent accuracy (64.73%) is achieved, when using Linear Discrimination Analysis (LDA) as the classification algorithm. The standard deviation of the results is 5.03. The electrode locations were then improved for the detection of emotion, by moving them from F1, F2, T3 and T4 to A1, F2, F7 and F8. The subject-dependent accuracy, using the improved locations, increased to 91.75% from 86.83% and 75% of participants achieved a classification accuracy higher than 90%, compared with only 16% of participants before improving the electrode arrangement

A Novel Power-Efficient Wireless Multi-channel Recording System for the Telemonitoring of Electroencephalography (EEG)

This research introduces the development of a novel EEG recording system that is modular, batteryless, and wireless (untethered) with the supporting theoretical foundation in wireless communications and related design elements and circuitry. Its modular construct overcomes the EEG scaling problem and makes it easier for reconfiguring the hardware design in terms of the number and placement of electrodes and type of standard EEG system contemplated for use. In this development, portability, lightweight, and applicability to other clinical applications that rely on EEG data are sought. Due to printer tolerance, the 3D printed cap consists of 61 electrode placements. This recording capacity can however extend from 21 (as in the international 10-20 systems) up to 61 EEG channels at sample rates ranging from 250 to 1000 Hz and the transfer of the raw EEG signal using a standard allocated frequency as a data carrier. The main objectives of this dissertation are to (1) eliminate the need for heavy mounted batteries, (2) overcome the requirement for bulky power systems, and (3) avoid the use of data cables to untether the EEG system from the subject for a more practical and less restrictive setting. Unpredictability and temporal variations of the EEG input make developing a battery-free and cable-free EEG reading device challenging. Professional high-quality and high-resolution analog front ends are required to capture non-stationary EEG signals at microvolt levels. The primary components of the proposed setup are the wireless power transmission unit, which consists of a power amplifier, highly efficient resonant-inductive link, rectification, regulation, and power management units, as well as the analog front end, which consists of an analog to digital converter, pre-amplification unit, filtering unit, host microprocessor, and the wireless communication unit. These must all be compatible with the rest of the system and must use the least amount of power possible while minimizing the presence of noise and the attenuation of the recorded signal A highly efficient resonant-inductive coupling link is developed to decrease power transmission dissipation. Magnetized materials were utilized to steer electromagnetic flux and decrease route and medium loss while transmitting the required energy with low dissipation. Signal pre-amplification is handled by the front-end active electrodes. Standard bio-amplifier design approaches are combined to accomplish this purpose, and a thorough investigation of the optimum ADC, microcontroller, and transceiver units has been carried out. We can minimize overall system weight and power consumption by employing battery-less and cable-free EEG readout system designs, consequently giving patients more comfort and freedom of movement. Similarly, the solutions are designed to match the performance of medical-grade equipment. The captured electrical impulses using the proposed setup can be stored for various uses, including classification, prediction, 3D source localization, and for monitoring and diagnosing different brain disorders. All the proposed designs and supporting mathematical derivations were validated through empirical and software-simulated experiments. Many of the proposed designs, including the 3D head cap, the wireless power transmission unit, and the pre-amplification unit, are already fabricated, and the schematic circuits and simulation results were based on Spice, Altium, and high-frequency structure simulator (HFSS) software. The fully integrated head cap to be fabricated would require embedding the active electrodes into the 3D headset and applying current technological advances to miniaturize some of the design elements developed in this dissertation

Developing a portable, customizable, single-channel EEG device for homecare and validating it against a commercial EEG device

There are several commercial electroencephalography (EEG) devices on the market; however, affordable devices are not versatile for diverse research applications. The purpose of this project was to investigate how to develop a low-cost, portable, single-channel EEG system for a research institute that could be used for neurofeedback-related applications in homecare. A device comparison was intended to examine what system requirements such a system would need to achieve the secondary objective of developing a neurofeedback application that demonstrates the functionalities of the new device. A portable, single-channel EEG device prototype was realized that consisted of an amplifier module called EEG Click, a single-board microcontroller, an electrode cable, some disposable wet electrode pads, and a custom 3D-printed headband. Three pieces of software were developed: firmware for the prototype, two supporting computer applications for data recording, and visual neurofeedback. The neurofeedback application replayed a first-person view roller coaster video at a varying frame rate based on the theta band's mean power spectral density (PSD). The prototype was compared against a commercial device, InteraXon MUSE 2 (Muse). Technical measurements included determining the amplitude-frequency characteristics and signal quality, such as signal-to-noise ratio (SNR), spurious-free dynamic range (SFDR), and total harmonic distortion (THD). Furthermore, four physiological measurements were performed on six human test subjects, aged between 21-31 (mean: 26.0, std: 3.11), to compare the altered brain activity and induced artifacts between the two devices. The four tests were respiratory exercise, head movement exercise, eye movement exercise, and paced auditory serial addition test (PASAT), where each measurement included several epochs with various stimuli. After the recordings, PSD was calculated for each bandpass filtered epoch, then the spectra were split into theta (4-8 Hz), alpha (8-12 Hz), and beta bands (12-30 Hz). The PSD values were averaged within each frequency band, and then these baseline-corrected mean values were the input for the repeated measures ANOVA statistical analysis. Results revealed that the amplitude-frequency characteristic of the prototype was low-pass filter-like and had a smaller slope than Muse's. The prototype's SNR, including and excluding the first five harmonics, was 6 dB higher, while SFDR and THD for the first five harmonics were roughly the same as Muse's. The two devices were comparable in detecting changes in most physiological measurements. Some differences between the two devices were that Muse was able to detect changes in respiratory activity in the beta band (F(8,16) = 2.510, p = .056), while the prototype was more sensitive to eye movement, especially lateral and circular eye movement in theta (F(2,8) = 9.144, p = .009) and alpha (F(2,8) = 6.095, p = .025) bands. A low-cost, portable EEG prototype was successfully realized and validated. The prototype was capable of performing homecare neurofeedback in the theta band. The results indicated it is worth exploring further the capabilities of the prototype. Since the sample size was too small, more complex physiological measurements with more test subjects would be more conclusive. Nevertheless, the findings are promising; the prototype may become a product once

Low-Power Human-Machine Interfaces: Analysis And Design

Human-Machine Interaction (HMI) systems, once used for clinical applications, have recently reached a broader set of scenarios, such as industrial, gaming, learning, and health tracking thanks to advancements in Digital Signal Processing (DSP) and Machine Learning (ML) techniques. A growing trend is to integrate computational capabilities into wearable devices to reduce power consumption associated with wireless data transfer while providing a natural and unobtrusive way of interaction. However, current platforms can barely cope with the computational complexity introduced by the required feature extraction and classification algorithms without compromising the battery life and the overall intrusiveness of the system. Thus, highly-wearable and real-time HMIs are yet to be introduced. Designing and implementing highly energy-efficient biosignal devices demands a fine-tuning to meet the constraints typically required in everyday scenarios. This thesis work tackles these challenges in specific case studies, devising solutions based on bioelectrical signals, namely EEG and EMG, for advanced hand gesture recognition. The implementation of these systems followed a complete analysis to reduce the overall intrusiveness of the system through sensor design and miniaturization of the hardware implementation. Several solutions have been studied to cope with the computational complexity of the DSP algorithms, including commercial single-core and open-source Parallel Ultra Low Power architectures, that have been selected accordingly also to reduce the overall system power consumption. By further adding energy harvesting techniques combined with the firmware and hardware optimization, the systems achieved self-sustainable operation or a significant boost in battery life. The HMI platforms presented are entirely programmable and provide computational power to satisfy the requirements of the studies applications while employing only a fraction of the CPU resources, giving the perspective of further application more advanced paradigms for the next generation of real-time embedded biosignal processing

A Driving Right Leg Circuit (DgRL) for Improved Common Mode Rejection in Bio-Potential Acquisition Systems

The paper presents a novel Driving Right Leg (DgRL) circuit designed to mitigate the effect of common mode signals deriving, say, from power line interferences. The DgRL drives the isolated ground of the instrumentation towards a voltage which is fixed with respect to the common mode potential on the subject, therefore minimizing common mode voltage at the input of the front-end. The paper provides an analytical derivation of the common mode rejection performances of DgRL as compared to the usual grounding circuit or Driven Right Leg (DRL) loop. DgRL is integrated in a bio-potential acquisition system to show how it can reduce the common mode signal of more than 70 dB with respect to standard patient grounding. This value is at least 30 dB higher than the reduction achievable with DRL, making DgRL suitable for single-ended front-ends, like those based on active electrodes. EEG signal acquisition is performed to show how the system can successfully cancel power line interference without any need for differential acquisition, signal post-processing or filtering