Verification, Analytical Validation, and Clinical Validation (V3): The Foundation of Determining Fit-for-Purpose for Biometric Monitoring Technologies (BioMeTs)

Digital medicine is an interdisciplinary field, drawing together stakeholders with expertize in engineering, manufacturing, clinical science, data science, biostatistics, regulatory science, ethics, patient advocacy, and healthcare policy, to name a few. Although this diversity is undoubtedly valuable, it can lead to confusion regarding terminology and best practices. There are many instances, as we detail in this paper, where a single term is used by different groups to mean different things, as well as cases where multiple terms are used to describe essentially the same concept. Our intent is to clarify core terminology and best practices for the evaluation of Biometric Monitoring Technologies (BioMeTs), without unnecessarily introducing new terms. We focus on the evaluation of BioMeTs as fit-for-purpose for use in clinical trials. However, our intent is for this framework to be instructional to all users of digital measurement tools, regardless of setting or intended use. We propose and describe a three-component framework intended to provide a foundational evaluation framework for BioMeTs. This framework includes (1) verification, (2) analytical validation, and (3) clinical validation. We aim for this common vocabulary to enable more effective communication and collaboration, generate a common and meaningful evidence base for BioMeTs, and improve the accessibility of the digital medicine field

An open platform for seamless sensor support in healthcare for the Internet of things

Population aging and increasing pressure on health systems are two issues that demand solutions. Involving and empowering citizens as active managers of their health represents a desirable shift from the current culture mainly focused on treatment of disease, to one also focused on continuous health management and well-being. Current developments in technological areas such as the Internet of Things (IoT), lead to new technological solutions that can aid this shift in the healthcare sector. This study presents the design, development, implementation and evaluation of a platform called Common Recognition and Identification Platform (CRIP), a part of the CareStore project, which aims at supporting caregivers and citizens to manage health routines in a seamless way. Specifically, the CRIP offers sensor-based support for seamless identification of users and health devices. A set of initial requirements was defined with a focus on usability limitations and current sensor technologies. The CRIP was designed and implemented using several technologies that enable seamless integration and interaction of sensors and people, namely Near Field Communication and fingerprint biometrics for identification and authentication, Bluetooth for communication with health devices and web services for wider integration with other platforms. Two CRIP prototypes were implemented and evaluated in laboratory during a period of eight months. The evaluations consisted of identifying users and devices, as well as seamlessly configure and acquire vital data from the last. Also, the entire Carestore platform was deployed in a nursing home where its usability was evaluated with caregivers. The evaluations helped assess that seamless identification of users and seamless configuration and communication with health devices is feasible and can help enable the IoT on healthcare applications. Therefore, the CRIP and similar platforms could be transformed into a valuable enabling technology for secure and reliable IoT deployments on the healthcare sector.This research work was supported under the European Framework Program FP7 Research for the Benefit of SMEs, project FP7-SME-2012-315158-CareStore. The authors would also like to acknowledge the work of all the members of the CareStore team, without whom this work would not be possible

A Survey on Modality Characteristics, Performance Evaluation Metrics, and Security for Traditional and Wearable Biometric Systems

Biometric research is directed increasingly towards Wearable Biometric Systems (WBS) for user authentication and identification. However, prior to engaging in WBS research, how their operational dynamics and design considerations differ from those of Traditional Biometric Systems (TBS) must be understood. While the current literature is cognizant of those differences, there is no effective work that summarizes the factors where TBS and WBS differ, namely, their modality characteristics, performance, security and privacy. To bridge the gap, this paper accordingly reviews and compares the key characteristics of modalities, contrasts the metrics used to evaluate system performance, and highlights the divergence in critical vulnerabilities, attacks and defenses for TBS and WBS. It further discusses how these factors affect the design considerations for WBS, the open challenges and future directions of research in these areas. In doing so, the paper provides a big-picture overview of the important avenues of challenges and potential solutions that researchers entering the field should be aware of. Hence, this survey aims to be a starting point for researchers in comprehending the fundamental differences between TBS and WBS before understanding the core challenges associated with WBS and its design

INTEGRATION OF INTERNET OF THINGS AND HEALTH RECOMMENDER SYSTEMS

The Internet of Things (IoT) has become a part of our lives and has provided many enhancements to day-to-day living. In this project, IoT in healthcare is reviewed. IoT-based healthcare is utilized in remote health monitoring, observing chronic diseases, individual fitness programs, helping the elderly, and many other healthcare fields. There are three main architectures of smart IoT healthcare: Three-Layer Architecture, Service-Oriented Based Architecture (SoA), and The Middleware-Based IoT Architecture. Depending on the required services, different IoT architecture are being used. In addition, IoT healthcare services, IoT healthcare service enablers, IoT healthcare applications, and IoT healthcare services focusing on Smartwatch are presented in this research. Along with IoT in smart healthcare, Health Recommender Systems integration with IoT is important. Main Recommender Systems including Content-based filtering, Collaborative-based filtering, Knowledge-based filtering, and Hybrid filtering with machine learning algorithms are described for the Health Recommender Systems. In this study, a framework is presented for the IoT-based Health Recommender Systems. Also, a case is investigated on how different algorithms can be used for Recommender Systems and their accuracy levels are presented. Such a framework can help with the health issues, for example, risk of going to see the doctor during pandemic, taking quick actions in any health emergencies, affordability of healthcare services, and enhancing the personal lifestyle using recommendations in non-critical conditions. The proposed framework can necessitate further development of IoT-based Health Recommender Systems so that people can mitigate their medical emergencies and live a healthy life

A New Trust Framework for E-Government in Cloud of Things

The concept of Cloud of Things becomes important for each e-government, facilitating its way of work, increasing its productivity and all that leading to cost savings. It will likely have a significant impact on the e-governments in the future. E-government diversity goals face many challenges. Trust is a major challenge when deploying Cloud of Things in e-government. In this paper, a new trust framework is proposed that supports trust between Internet of Things devices interconnected to the Cloud in order to support e-government services to be delivered in trusted manner. The proposed framework has been applied to a use case study to ensure the trustworthiness of the proposed framework in a real mission. The results show that the proposed trust framework is useful to ensuring a trust environment for Cloud of Things in order to continue providing and gathering data needed to provide services to users through the E-government services

Enhancing Security in Internet of Healthcare Application using Secure Convolutional Neural Network

The ubiquity of Internet of Things (IoT) devices has completely changed the healthcare industry by presenting previously unheard-of potential for remote patient monitoring and individualized care. In this regard, we suggest a unique method that makes use of Secure Convolutional Neural Networks (SCNNs) to improve security in Internet-of-Healthcare (IoH) applications. IoT-enabled healthcare has advanced as a result of the integration of IoT technologies, giving it impressive data processing powers and large data storage capacity. This synergy has led to the development of an intelligent healthcare system that is intended to remotely monitor a patient's medical well-being via a wearable device as a result of the ongoing advancement of the Industrial Internet of Things (IIoT). This paper focuses on safeguarding user privacy and easing data analysis. Sensitive data is carefully separated from user-generated data before being gathered. Convolutional neural network (CNN) technology is used to analyse health-related data thoroughly in the cloud while scrupulously protecting the privacy of the consumers.The paper provide a secure access control module that functions using user attributes within the IoT-Healthcare system to strengthen security. This module strengthens the system's overall security and privacy by ensuring that only authorised personnel may access and interact with the sensitive health data. The IoT-enabled healthcare system gets the capacity to offer seamless remote monitoring while ensuring the confidentiality and integrity of user information thanks to this integrated architecture

Cloud-based platform for intelligent healthcare monitoring and risk prevention in hazardous manufacturing contexts

This paper presents an intelligent cloud-based platform for workers healthcare monitoring and risk prevention in potentially hazardous manufacturing contexts. The platform is structured according to sequential modules dedicated to data acquisition, processing and decision-making support. Several sensors and data sources, including smart wearables, machine tool embedded sensors and environmental sensors, are employed for data collection, comprising information on offline clinical background, operational and environmental data. The cloud data processing module is responsible for extracting relevant features from the acquired data in order to feed a machine learning-based decision-making support system. The latter provides a classification of workers’ health status so that a prompt intervention can be performed in particularly challenging scenarios