Ontology translation approaches for interoperability: A case study with Protege-2000 and WebODE

We describe four ontology translation approaches that can be used to exchange ontologies between ontology tools and/or ontology languages. These approaches are analysed with regard to two main features: how they preserve the ontology semantics after the translation process (aka semantic or consequence preservation) and how they allow final users and ontology-based applications to understand the resulting ontology in the target format (aka pragmatic preservation). These approaches are illustrated with practical examples that show how they can be applied to achieve interoperability between the ontology tools Protege-2000 and WebODE

A Genetic Programming Strategy to Induce Logical Rules for Clinical Data Analysis

[EN]This paper proposes a machine learning approach dealing with genetic programming to build classifiers through logical rule induction. In this context, we define and test a set of mutation operators across from different clinical datasets to improve the performance of the proposal for each dataset. The use of genetic programming for rule induction has generated interesting results in machine learning problems. Hence, genetic programming represents a flexible and powerful evolutionary technique for automatic generation of classifiers. Since logical rules disclose knowledge from the analyzed data, we use such knowledge to interpret the results and filter the most important features from clinical data as a process of knowledge discovery. The ultimate goal of this proposal is to provide the experts in the data domain with prior knowledge (as a guide) about the structure of the data and the rules found for each class, especially to track dichotomies and inequality. The results reached by our proposal on the involved datasets have been very promising when used in classification tasks and compared with other methods

Bioinformatics Applications Based On Machine Learning

The great advances in information technology (IT) have implications for many sectors, such as bioinformatics, and has considerably increased their possibilities. This book presents a collection of 11 original research papers, all of them related to the application of IT-related techniques within the bioinformatics sector: from new applications created from the adaptation and application of existing techniques to the creation of new methodologies to solve existing problems