Osteopathy Complete

The human system is, to all intents and purposes, a wonderful machine, capable of running for an indefinite period of time, unless interfered with by accidents, dislocations, contraction of muscles, obstruction of the nerve-force, or the circulation of the nutritive fluids of the body. The author consulted such works as Gx\u27ay, Landois, Saunders, and Musser, with an earnest desire to advance the cause of Osteopathy, and endeavored to be accurate, concise, and modern.https://digitalcommons.pcom.edu/classic_med_works/1009/thumbnail.jp

College and Clinical Record

Published from 1880-1899, the College and Clinical Record was a monthly medical journal put out by Jefferson Medical College students and graduates. It commonly included printed lectures, conference proceedings, original articles, reminiscences, obituaries notices, marriage announcements, and college news. According to its first publication, The CLINICAL RECORD has been instituted more particularly for the purpose of conveying to those interested the most reliable intelligence of current affairs at the Jefferson Medical College, and of furnishing a means of intercourse between graduates of the school... It is especially intended to impart to the graduates and students of the College accurate and elaborate reports of the medical, surgical, and gynaecological clinics held by the members of the Faculty and Hospital Staff, with notes of peculiarities of treatment of cases in the hospital of the College. The editors are two of its graduates, who are keenly sensible of the desirability of preserving as much as possible of the valuable instruction of the \u27Old Jeff,\u27 as it is familiarly known.https://jdc.jefferson.edu/jmc_publications/1000/thumbnail.jp

William Osler: Original Papers 1907-1919

Part 1: 1907-1908 The Royal Medical Society of Edinburg, 1907 On the Library of a Medical School, 1907 On Telangiectasis Circumscripta Universalis, 1907 A Clinical Lecture on Abdominal Tumours Associated with Disease of the Testicle, 1907 A Clinical Lecture on Erythraemia, 1908 Vienna after Thirty-Four Years, 1908 Endocardites Infectieuses Chroniques, 1908 Part 2: 1909 Chronic Infectious Endocarditis, 1909 What the Public Can Do in the Fight Against Tuberculosis, 1909 Annual Oration on the Occasion of the Opening of the New Building of the Medical and Chirurgical Faculty of the State of Maryland, May 13, 1909 The Medical Library in Post-Graduate Work, 1909 The Treatment of Disease, 1909 Part 3: 1910-1911 The Pupil Symptoms in Thoracic Aneurysm, 1910 The Lumleian Lectures on Angina Pectoris, 1910 Certain Vasomotor, Sensory, and Muscular Phenomena Associated with Cervical Rib, 1910 An Address on the Hospital Unit in University Work, 1911 Sulle Telangiectasie Emorragiche Ereditarie, 1911 Transient Attacks of Aphasia and Paralyses in States of High Blood Pressure and Arterio-Sclerosis, 1911 The Pathological Institute of a General Hospital, 1911 Part 4: 1912-1914 An Address on High Blood Pressure: its Associations, Advantages, and Disadvantages, 1912 Specialism in the General Hospital, 1913 Syphilis of the Liver with the Picture of Banti’s Disease, 1913 An Introductory Address on Examinations, Examiners, and Examinees, 1913 The Medical Clinic: a retrospect and a Forecast, 1914 Part 5: 1915-1919 Remarks on the Diagnosis of Polycystic Kidney, 1915 The War and Typhoid Fever, 1914/15 The Cerebro-Spinal Fever in Camps and Barracks, 1915 Remarks on Arterio-Venous Aneurysm, 1915 Nerve & “Nerves”, 1915 Intensive Work in Science at the Public Schools in Relation to the Curriculum, 1916 Creators, Transmuters, and Transmitters, 1916 Annual Oration on the Campaign Against Syphilis, 1917 The First Printed Documents relating to Modern Surgical Anaesthesia, 1918 Observations on the Severe Anaemias of Pregnancy and the Post-Partum State, 1919 Typhoid Spine, 1919https://digitalcommons.library.tmc.edu/osler/1002/thumbnail.jp

Ultrasensitive detection of toxocara canis excretory-secretory antigens by a nanobody electrochemical magnetosensor assay.

peer reviewedHuman Toxocariasis (HT) is a zoonotic disease caused by the migration of the larval stage of the roundworm Toxocara canis in the human host. Despite of being the most cosmopolitan helminthiasis worldwide, its diagnosis is elusive. Currently, the detection of specific immunoglobulins IgG against the Toxocara Excretory-Secretory Antigens (TES), combined with clinical and epidemiological criteria is the only strategy to diagnose HT. Cross-reactivity with other parasites and the inability to distinguish between past and active infections are the main limitations of this approach. Here, we present a sensitive and specific novel strategy to detect and quantify TES, aiming to identify active cases of HT. High specificity is achieved by making use of nanobodies (Nbs), recombinant single variable domain antibodies obtained from camelids, that due to their small molecular size (15kDa) can recognize hidden epitopes not accessible to conventional antibodies. High sensitivity is attained by the design of an electrochemical magnetosensor with an amperometric readout with all components of the assay mixed in one single step. Through this strategy, 10-fold higher sensitivity than a conventional sandwich ELISA was achieved. The assay reached a limit of detection of 2 and15 pg/ml in PBST20 0.05% or serum, spiked with TES, respectively. These limits of detection are sufficient to detect clinically relevant toxocaral infections. Furthermore, our nanobodies showed no cross-reactivity with antigens from Ascaris lumbricoides or Ascaris suum. This is to our knowledge, the most sensitive method to detect and quantify TES so far, and has great potential to significantly improve diagnosis of HT. Moreover, the characteristics of our electrochemical assay are promising for the development of point of care diagnostic systems using nanobodies as a versatile and innovative alternative to antibodies. The next step will be the validation of the assay in clinical and epidemiological contexts

Английский язык для биологии и медицины: бакалавров и магистров

Терминология в условиях ускорения научно-технического прогресса приобретает особое значение. Она является источником получения информации, инструментом освоения специальности. Любая область науки и техники находит своё выражение в терминах. Практически нет ни одной области знания, которая изучается, не владея терминологией. Медицинская терминология является одним из специфических пластов лексики, которая в силу особенностей структурно-семантического, словообразовательного и стилистического характера отличается от общеупотребительных слов и занимает особое место в лексической системе языка. Медицинская терминология – это пласт лексического фонда со своими специфическими особенностями, ибо в каждом профессиональном подъязыке существует номенклатурная лексика, соотносимая с определенными реалиями и объектами. Особенность словарного состава терминологии заключается в том, что её номены представлены в ней шире, многообразнее, чем в других лексических подсистемах. Выбор английского языка в качестве второго языка сопоставительного исследования обусловлен его все возрастающей коммуникативной ролью в мировом сообществе, популярностью, сегодняшней жизненной необходимостью. Учебник предназначен для бакалавров и магистров в сфере биологии и медицины. Он состоит из 4 глав и параграфов. В каждой главе дается целый ряд основных лексических номенов, помогающие понять сложные тексты из неадаптированных источников этой сферы. Также прилагается несколько десятков упражнений для лучшего понимания и усвоения данного материала. Красочные иллюстрации наглядно демонстрируют основные положения и понятия в сфере биологии и медицины